Evaluation of refolding conditions for a recombinant human interleukin-3 variant (daniplestim)

Biotechnology and Applied Biochemistry

Volumn 30, Issue 2, 1999, Pages 163-170

  Boyle, Denis M ^a   McKinnie, Russell E ^a   Joy, William D ^a   Violand, Bernard N ^a   McLaughlin, Joseph K ^a   Landis, Bryan H ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DITHIOTHREITOL; GUANIDINE; RECOMBINANT INTERLEUKIN 3; RECOMBINANT PROTEIN; UREA;

ARTICLE; CELL INCLUSION; CIRCULAR DICHROISM; DISSOLUTION; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; PH; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TIME;

ESCHERICHIA COLI;

EID: 0346399510     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Metcalf, D. (1991) Science 254, 529-533
2. Ganser, A. (1993) Cancer Invest. 11, 212-218
3. Thomas, J. W., Baum, C. M., Hood, W. F., Klein, B., Monahan, J. B., Paik, K., Staten, N., Abrams, M. and McKearn, J. P. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 3779-3783
4. Olins, P. O., Devine, C. S., Rangwala, S. and Kavka, K. (1988) Gene 73, 227-235
5. Olins, P. O., Bauer, S. C., Braford-Goldberg, S., Sterbenz, K., Polazzi, J. O., Caparon, M. H., Klein, B. K., Easton, A. M., Paik, K., Klover, J. A., Thiele, B. R. and McKearn, J. P. (1995) J. Biol. Chem. 270, 23754-23760
6. Chen, Y. H., Yang, J. T. and Martinez, H. M. (1972) Biochemistry 11, 4120-4131
7. Pace, C. N., Shirley, B. A. and Thomson, J. A. (1989) In Protein Structure: A Practical Approach (Creighton, T.E., ed.), pp. 311-330, IRL Press, Oxford
8. Walsh, S. and Diamond, D. (1995) Talanta 42, 561-572
9. Feng, Y.-Q., Klein, B. K., Vu, L., Aykent, S. and McWherter, C. A. (1995) Biochemistry 34, 6540-6551
10. Feng, Y.-Q., Klein, B. K. and McWherter, C. A. (1996) J. Mol. Biol. 259, 524-541
11. Manning, M. C., Patel, K. and Brochardt, R. T. (1989) Pharm. Res. 6, 903-918