-
1
-
-
0035522894
-
Two genetic hits (more or less) to cancer
-
Knudson AG. Two genetic hits (more or less) to cancer. Nat Rev Cancer, 1: 157-162, 2001.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 157-162
-
-
Knudson, A.G.1
-
2
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG, Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA, 68: 820-823, 1971.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 820-823
-
-
Knudson Jr., A.G.1
-
3
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
Friend SH, Bernards R, Rogelj S, et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature, 323: 643-646, 1986.
-
(1986)
Nature
, vol.323
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogelj, S.3
-
4
-
-
0034455671
-
Cell cycle control and cancer
-
Sherr CJ. Cell cycle control and cancer. Harvey Lect 2000; 96: 73-92.
-
(2000)
Harvey Lect
, vol.96
, pp. 73-92
-
-
Sherr, C.J.1
-
5
-
-
0001510491
-
The RB p53 pathways in cancer
-
Sherr CJ and McCormick F. The RB and p53 pathways in cancer. Cancer Cell, 2: 103-112, 2002.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
McCormick, F.2
-
6
-
-
0037268338
-
The Fanconi anaemia/BRCA pathway
-
D'Andrea AD and Grompe M. The Fanconi anaemia/BRCA pathway. Nat Rev Cancer, 3: 23-34, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 23-34
-
-
D'Andrea, A.D.1
Grompe, M.2
-
7
-
-
0037447303
-
Increased error-prone NHEJ activity in myeloid leukemias is associated with DNA damage at sites that recruit key nonhomologous end-joining proteins
-
Brady N, Gaymes TJ, Cheung M, et al. Increased error-prone NHEJ activity in myeloid leukemias is associated with DNA damage at sites that recruit key nonhomologous end-joining proteins. Cancer Res, 63: 1798-1805, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 1798-1805
-
-
Brady, N.1
Gaymes, T.J.2
Cheung, M.3
-
8
-
-
0035396754
-
Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies
-
Poppe B, Van Limbergen H, Van Roy N, et al. Chromosomal aberrations in Bloom syndrome patients with myeloid malignancies. Cancer Genet Cytogenet, 128: 39-42, 2001.
-
(2001)
Cancer Genet Cytogenet
, vol.128
, pp. 39-42
-
-
Poppe, B.1
Van Limbergen, H.2
Van Roy, N.3
-
9
-
-
0034489683
-
BLM, the Bloom's syndrome protein, varies during the cell cycle in its amount, distribution, and co-localization with other nuclear proteins
-
Sanz MM, Proytcheva M, Ellis NA, et al. BLM, the Bloom's syndrome protein, varies during the cell cycle in its amount, distribution, and co-localization with other nuclear proteins. Cytogenet Cell Genet, 91: 217-223, 2000.
-
(2000)
Cytogenet Cell Genet
, vol.91
, pp. 217-223
-
-
Sanz, M.M.1
Proytcheva, M.2
Ellis, N.A.3
-
10
-
-
0037365789
-
ATM related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer, 3: 155-168, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
11
-
-
0037080679
-
Sensing of intermediates in V(D)J recombination by ATM
-
Perkins EJ, Nair A, Cowley DO, et al. Sensing of intermediates in V(D)J recombination by ATM. Genes Dev, 16: 159-164, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 159-164
-
-
Perkins, E.J.1
Nair, A.2
Cowley, D.O.3
-
12
-
-
0035997348
-
V(D)J recombination: RAG proteins, repair factors, and regulation
-
Gellert M. V(D)J recombination: RAG proteins, repair factors, and regulation. Annu Rev Biochem 71: 101-132, 2002.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 101-132
-
-
Gellert, M.1
-
13
-
-
0030800094
-
Trans-rearrangements and the risk of lymphoid malignancy
-
Kirsch IR. Trans-rearrangements and the risk of lymphoid malignancy. Ann Oncol, 8 Suppl 2: 45-48, 1997.
-
(1997)
Ann Oncol
, vol.8
, Issue.SUPPL. 2
, pp. 45-48
-
-
Kirsch, I.R.1
-
14
-
-
0031170828
-
Lymphocyte-specific genomic instability and risk of lymphoid malignancy
-
Kirsch IR and Lista F. Lymphocyte-specific genomic instability and risk of lymphoid malignancy. Semin Immunol, 9: 207-215, 1997.
-
(1997)
Semin Immunol
, vol.9
, pp. 207-215
-
-
Kirsch, I.R.1
Lista, F.2
-
15
-
-
0034284341
-
Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice
-
Liyanage M, Weaver Z, Barlow C, et al. Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice. Blood, 96: 1940-1946, 2000.
-
(2000)
Blood
, vol.96
, pp. 1940-1946
-
-
Liyanage, M.1
Weaver, Z.2
Barlow, C.3
-
16
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
Barlow C, Hirotsune S, Paylor R, et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell, 86: 159-171, 1996.
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
-
17
-
-
0033563099
-
Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma
-
Liao MJ and Van Dyke T. Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma. Genes Dev, 13: 1246-1250, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 1246-1250
-
-
Liao, M.J.1
Van Dyke, T.2
-
18
-
-
0034612377
-
Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice
-
Petiniot LK, Weaver Z, Barlow C, et al. Recombinase-activating gene (RAG) 2-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice. Proc Natl Acad Sci USA, 97: 6664-6669, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6664-6669
-
-
Petiniot, L.K.1
Weaver, Z.2
Barlow, C.3
-
19
-
-
0347274293
-
A molecular genetic analysis of lymphoid neoplasia
-
Rich RR, Fleisher TA, Shearer WT, Kotzin BL, Schroeder HW, eds. London: Mosby
-
Izraeli S, Kirsch IR. A molecular genetic analysis of lymphoid neoplasia. In: Rich RR, Fleisher TA, Shearer WT, Kotzin BL, Schroeder HW, eds. Clinical Immunology, Principles and Practice. Vol. 2. London: Mosby, 93.1-93.18, 2001.
-
(2001)
Clinical Immunology, Principles and Practice
, vol.2
, pp. 931-9318
-
-
Izraeli, S.1
Kirsch, I.R.2
-
20
-
-
0036153956
-
Down syndrome, transient myeloproliferative syndrome, and leukemia: Bridging development and neoplasia
-
Arceci RJ. Down syndrome, transient myeloproliferative syndrome, and leukemia: bridging development and neoplasia. J Pediatr Hematol Oncol, 24: 1, 2002.
-
(2002)
J Pediatr Hematol Oncol
, vol.24
, pp. 1
-
-
Arceci, R.J.1
-
21
-
-
0035412104
-
Pattern of malignant disorders in individuals with Down's syndrome
-
Hasle H. Pattern of malignant disorders in individuals with Down's syndrome. Lancet Oncol 2: 429-436, 2001.
-
(2001)
Lancet Oncol
, vol.2
, pp. 429-436
-
-
Hasle, H.1
-
22
-
-
0037325661
-
A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases
-
Hasle H, Niemeyer CM, Chessells JM, et al. A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases. Leukemia, 17: 277-282, 2003.
-
(2003)
Leukemia
, vol.17
, pp. 277-282
-
-
Hasle, H.1
Niemeyer, C.M.2
Chessells, J.M.3
-
23
-
-
0037355255
-
Transient leukaemia - A benign form of leukaemia in newborn infants with trisomy 21
-
Zipursky A. Transient leukaemia - a benign form of leukaemia in newborn infants with trisomy 21. Br J Haematol, 120: 930-938, 2003.
-
(2003)
Br J Haematol
, vol.120
, pp. 930-938
-
-
Zipursky, A.1
-
25
-
-
0023459992
-
Megakaryoblastic leukemia and Down's syndrome: A review
-
Zipursky A, Peeters M, Poon A. Megakaryoblastic leukemia and Down's syndrome: a review. Pediatr Hematol Oncol, 4: 211-230, 1987.
-
(1987)
Pediatr Hematol Oncol
, vol.4
, pp. 211-230
-
-
Zipursky, A.1
Peeters, M.2
Poon, A.3
-
26
-
-
0032941980
-
Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome
-
Zipursky A, Brown EJ, Christensen H, Doyle J. Transient myeloproliferative disorder (transient leukemia) and hematologic manifestations of Down syndrome. Clin Lab Med, 19: 157-167, vii, 1999.
-
(1999)
Clin Lab Med
, vol.19
, pp. 157-167
-
-
Zipursky, A.1
Brown, E.J.2
Christensen, H.3
Doyle, J.4
-
27
-
-
0030986775
-
Leukemia and/or myeloproliferative syndrome in neonates with Down syndrome
-
Zipursky A, Brown E, Christensen H, et al. Leukemia and/or myeloproliferative syndrome in neonates with Down syndrome. Semin Perinatol 21: 97-101, 1997.
-
(1997)
Semin Perinatol
, vol.21
, pp. 97-101
-
-
Zipursky, A.1
Brown, E.2
Christensen, H.3
-
28
-
-
0036636857
-
Core-binding factors in haematopoiesis and leukaemia
-
Speck NA and Gilliland DG. Core-binding factors in haematopoiesis and leukaemia. Nat Rev Cancer 2: 502-513, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 502-513
-
-
Speck, N.A.1
Gilliland, D.G.2
-
29
-
-
0032830638
-
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
-
Song WJ, Sullivan MG, Legare RD, et al. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nature Genet, 23: 166-175, 1999.
-
(1999)
Nature Genet
, vol.23
, pp. 166-175
-
-
Song, W.J.1
Sullivan, M.G.2
Legare, R.D.3
-
30
-
-
0036736555
-
Mutation of the AML1/RUNX1 gene in a transient myeloproliferative disorder patient with Down syndrome
-
Taketani T, Taki T, Takita J, et al. Mutation of the AML1/RUNX1 gene in a transient myeloproliferative disorder patient with Down syndrome. Leukemia, 16: 1866-1867, 2002.
-
(2002)
Leukemia
, vol.16
, pp. 1866-1867
-
-
Taketani, T.1
Taki, T.2
Takita, J.3
-
31
-
-
0036727413
-
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J, Greene M, McDevitt MA, et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nature Genet, 32: 148-152, 2002.
-
(2002)
Nature Genet
, vol.32
, pp. 148-152
-
-
Wechsler, J.1
Greene, M.2
McDevitt, M.A.3
-
32
-
-
0037906527
-
Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
-
Groet J, McElwaine S, Spinelli M, et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet, 361: 1617-1620, 2003.
-
(2003)
Lancet
, vol.361
, pp. 1617-1620
-
-
Groet, J.1
McElwaine, S.2
Spinelli, M.3
-
33
-
-
0038142350
-
GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome
-
Hitzler JK, Cheung J, Li Y, et al. GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood, 101: 4301-4304, 2003.
-
(2003)
Blood
, vol.101
, pp. 4301-4304
-
-
Hitzler, J.K.1
Cheung, J.2
Li, Y.3
-
34
-
-
0038142390
-
Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis
-
Mundschau G, Gurbuxani S, Gamis AS, et al. Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis. Blood, 101: 4298-4300, 2003.
-
(2003)
Blood
, vol.101
, pp. 4298-4300
-
-
Mundschau, G.1
Gurbuxani, S.2
Gamis, A.S.3
-
35
-
-
0042243593
-
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
-
Rainis L, Bercovich D, Strehl S, et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood, 102: 981-986, 2003.
-
(2003)
Blood
, vol.102
, pp. 981-986
-
-
Rainis, L.1
Bercovich, D.2
Strehl, S.3
-
36
-
-
0029558618
-
Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor
-
Calligaris R, Bottardi S, Cogoi S, et al. Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor. Proc Natl Acad Sci USA, 92: 11598-11602, 1995.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11598-11602
-
-
Calligaris, R.1
Bottardi, S.2
Cogoi, S.3
-
37
-
-
0037047059
-
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis
-
Chang AN, Cantor AB, Fujiwara Y, et al. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis. Proc Natl Acad Sci USA, 99: 9237-9242, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9237-9242
-
-
Chang, A.N.1
Cantor, A.B.2
Fujiwara, Y.3
-
38
-
-
0037071383
-
Transcriptional regulation of erythropoiesis: An affair involving multiple partners
-
Cantor AB and Orkin SH. Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene, 21: 3368-3376, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 3368-3376
-
-
Cantor, A.B.1
Orkin, S.H.2
-
39
-
-
0036892750
-
GATA1 - A player in normal and leukemic megakaryopoiesis
-
Hitzler JK. GATA1 - A player in normal and leukemic megakaryopoiesis. Pediatr Res, 52: 831, 2002.
-
(2002)
Pediatr Res
, vol.52
, pp. 831
-
-
Hitzler, J.K.1
-
40
-
-
0032227812
-
Transcription factor GATA-1 in megakaryocyte development
-
Orkin SH, Shivdasani RA, Fujiwara Y, McDevitt MA. Transcription factor GATA-1 in megakaryocyte development. Stem Cells, 16 Suppl 2: 79-83, 1998.
-
(1998)
Stem Cells
, vol.16
, Issue.SUPPL. 2
, pp. 79-83
-
-
Orkin, S.H.1
Shivdasani, R.A.2
Fujiwara, Y.3
McDevitt, M.A.4
-
41
-
-
0037013924
-
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo
-
Yu C, Cantor AB, Yang H, et al. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J Exp Med, 195: 1387-1395, 2002.
-
(2002)
J Exp Med
, vol.195
, pp. 1387-1395
-
-
Yu, C.1
Cantor, A.B.2
Yang, H.3
-
42
-
-
0030926006
-
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
-
Shivdasani RA, Fujiwara Y, McDevitt MA, Orkin SH. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. Embo J, 16: 3965-3973, 1997.
-
(1997)
EMBO J
, vol.16
, pp. 3965-3973
-
-
Shivdasani, R.A.1
Fujiwara, Y.2
McDevitt, M.A.3
Orkin, S.H.4
-
43
-
-
0037105495
-
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction
-
Yu C, Niakan KK, Matsushita M, et al. X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction. Blood, 100: 2040-2045, 2002.
-
(2002)
Blood
, vol.100
, pp. 2040-2045
-
-
Yu, C.1
Niakan, K.K.2
Matsushita, M.3
-
44
-
-
0034052854
-
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
-
Nichols KE, Crispino JD, Poncz M, et al. Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. Nature Genet, 24: 266-270, 2000.
-
(2000)
Nature Genet
, vol.24
, pp. 266-270
-
-
Nichols, K.E.1
Crispino, J.D.2
Poncz, M.3
-
45
-
-
0035525746
-
X-linked thrombocytopenia caused by a novel mutation of GATA-1
-
Mehaffey MG, Newton AL, Gandhi MJ, et al. X-linked thrombocytopenia caused by a novel mutation of GATA-1. Blood, 98: 2681-2688, 2001.
-
(2001)
Blood
, vol.98
, pp. 2681-2688
-
-
Mehaffey, M.G.1
Newton, A.L.2
Gandhi, M.J.3
-
46
-
-
0038819114
-
RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation
-
Elagib KE, Racke FK, Mogass M, et al. RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation. Blood, 101: 4333-4341, 2003.
-
(2003)
Blood
, vol.101
, pp. 4333-4341
-
-
Elagib, K.E.1
Racke, F.K.2
Mogass, M.3
-
47
-
-
0036156452
-
Telomerase and the benign and malignant megakaryoblastic leukemias of Down syndrome
-
Holt SE, Brown EJ, Zipursky A. Telomerase and the benign and malignant megakaryoblastic leukemias of Down syndrome. J Pediatr Hematol Oncol, 24: 14-17, 2002.
-
(2002)
J Pediatr Hematol Oncol
, vol.24
, pp. 14-17
-
-
Holt, S.E.1
Brown, E.J.2
Zipursky, A.3
-
48
-
-
0037441871
-
Transcriptional regulation of the cystathionine-beta-synthase gene in Down syndrome and non-Down syndrome megakaryocytic leukemia cell lines
-
Ge Y, Jensen TL, Matherly LH, Taub JW. Transcriptional regulation of the cystathionine-beta-synthase gene in Down syndrome and non-Down syndrome megakaryocytic leukemia cell lines. Blood, 101: 1551-1557, 2003.
-
(2003)
Blood
, vol.101
, pp. 1551-1557
-
-
Ge, Y.1
Jensen, T.L.2
Matherly, L.H.3
Taub, J.W.4
-
49
-
-
0033566994
-
Expression of chromosome 21-localized genes in acute myeloid leukemia: Differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin
-
Taub JW, Huang X, Matherly LH, et al. Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin. Blood, 94: 1393-1400, 1999.
-
(1999)
Blood
, vol.94
, pp. 1393-1400
-
-
Taub, J.W.1
Huang, X.2
Matherly, L.H.3
-
50
-
-
0029757963
-
Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic-Cu/Zn superoxide dismutase neurons
-
Bar-Peled O, Korkotian E, Segal M, Groner Y. Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic-Cu/Zn superoxide dismutase neurons. Proc Natl Acad Sci USA, 93: 8530-8535, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8530-8535
-
-
Bar-Peled, O.1
Korkotian, E.2
Segal, M.3
Groner, Y.4
-
51
-
-
0035794540
-
Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice
-
Peter Y, Rotman G, Lotem J, et al. Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice. Embo J, 20: 1538-1546, 2001.
-
(2001)
EMBO J
, vol.20
, pp. 1538-1546
-
-
Peter, Y.1
Rotman, G.2
Lotem, J.3
-
52
-
-
0028839912
-
Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: Implications for Down syndrome
-
Peled-Kamar M, Lotem J, Okon E, et al. Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome. Embo J, 14: 4985-4993, 1995.
-
(1995)
Embo J
, vol.14
, pp. 4985-4993
-
-
Peled-Kamar, M.1
Lotem, J.2
Okon, E.3
-
53
-
-
0033991491
-
The role of p53 in megakaryocyte differentiation and the megakaryocytic leukemias of Down syndrome
-
Malkin D, Brown EJ, Zipursky A. The role of p53 in megakaryocyte differentiation and the megakaryocytic leukemias of Down syndrome. Cancer Genet Cytogenet, 116: 1-5, 2000.
-
(2000)
Cancer Genet Cytogenet
, vol.116
, pp. 1-5
-
-
Malkin, D.1
Brown, E.J.2
Zipursky, A.3
-
54
-
-
0033050457
-
Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7
-
European Working Group on MDS in Childhood (EWOG-MDS)
-
Hasle H, Arico M, Basso G, et al. Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7. European Working Group on MDS in Childhood (EWOG-MDS). Leukemia, 13: 376-385, 1999.
-
(1999)
Leukemia
, vol.13
, pp. 376-385
-
-
Hasle, H.1
Arico, M.2
Basso, G.3
-
55
-
-
0030843626
-
Juvenile myelomonocytic leukemia
-
Arico M, Biondi A, Pui CH. Juvenile myelomonocytic leukemia. Blood, 90: 479-488, 1997.
-
(1997)
Blood
, vol.90
, pp. 479-488
-
-
Arico, M.1
Biondi, A.2
Pui, C.H.3
-
56
-
-
0030977399
-
Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases
-
European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS)
-
Niemeyer CM, Arico M, Basso G, et al. Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS). Blood, 89: 3534-3543, 1997.
-
(1997)
Blood
, vol.89
, pp. 3534-3543
-
-
Niemeyer, C.M.1
Arico, M.2
Basso, G.3
-
57
-
-
0026063878
-
Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors
-
Emanuel PD, Bates LJ, Castleberry RP, et al. Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors. Blood, 77: 925-929, 1991.
-
(1991)
Blood
, vol.77
, pp. 925-929
-
-
Emanuel, P.D.1
Bates, L.J.2
Castleberry, R.P.3
-
58
-
-
0033674591
-
Malignancy in neurofibromatosis type 1
-
Korf BR. Malignancy in neurofibromatosis type 1. Oncologist, 5: 477-485, 2000.
-
(2000)
Oncologist
, vol.5
, pp. 477-485
-
-
Korf, B.R.1
-
59
-
-
0031424378
-
Role of the NF1 gene in leukemogenesis and myeloid growth control
-
O'Marcaigh AS and Shannon KM. Role of the NF1 gene in leukemogenesis and myeloid growth control. J Pediatr Hematol Oncol, 19: 551-554, 1997.
-
(1997)
J Pediatr Hematol Oncol
, vol.19
, pp. 551-554
-
-
O'Marcaigh, A.S.1
Shannon, K.M.2
-
60
-
-
0030947237
-
Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
-
Side L, Taylor B, Cayouette M, et al. Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders. N Engl J Med, 336:1713-1720, 1997.
-
(1997)
N Engl J Med
, vol.336
, pp. 1713-1720
-
-
Side, L.1
Taylor, B.2
Cayouette, M.3
-
61
-
-
0032125716
-
Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1
-
Side LE, Emanuel PD, Taylor B, et al. Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1. Blood 92: 267-272, 1998.
-
(1998)
Blood
, vol.92
, pp. 267-272
-
-
Side, L.E.1
Emanuel, P.D.2
Taylor, B.3
-
62
-
-
0031875457
-
Analysis of neurofibromatosis type 1 gene mutation in juvenile chronic myelogenous leukemia
-
Watanabe I, Horiuchi T, Hatta N, et al. Analysis of neurofibromatosis type 1 gene mutation in juvenile chronic myelogenous leukemia. Acta Haematol, 100: 22-25, 1998.
-
(1998)
Acta Haematol
, vol.100
, pp. 22-25
-
-
Watanabe, I.1
Horiuchi, T.2
Hatta, N.3
-
63
-
-
0029908346
-
Patterns of hematopoietic lineage involvement in children with neurofibromatosis type 1 and malignant myeloid disorders
-
Miles DK, Freedman MH, Stephens K, et al. Patterns of hematopoietic lineage involvement in children with neurofibromatosis type 1 and malignant myeloid disorders. Blood, 88: 4314-4320, 1996.
-
(1996)
Blood
, vol.88
, pp. 4314-4320
-
-
Miles, D.K.1
Freedman, M.H.2
Stephens, K.3
-
64
-
-
0034665775
-
Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell
-
Cooper LJ, Shannon KM, Loken MR, et al. Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell. Blood, 96: 2310-2313, 2000.
-
(2000)
Blood
, vol.96
, pp. 2310-2313
-
-
Cooper, L.J.1
Shannon, K.M.2
Loken, M.R.3
-
65
-
-
0028831774
-
Clonality in juvenile chronic myelogenous leukemia
-
Busque L, Gilliland DG, Prchal JT, et al. Clonality in juvenile chronic myelogenous leukemia. Blood, 85: 21-30, 1995.
-
(1995)
Blood
, vol.85
, pp. 21-30
-
-
Busque, L.1
Gilliland, D.G.2
Prchal, J.T.3
-
66
-
-
0033982718
-
NF1 and GM-CSF interact in myeloid leukemogenesis
-
Birnbaum RA, O'Marcaigh A, Wardak Z, et al. NF1 and GM-CSF interact in myeloid leukemogenesis. Mol Cell, 5: 189-195, 2000.
-
(2000)
Mol Cell
, vol.5
, pp. 189-195
-
-
Birnbaum, R.A.1
O'Marcaigh, A.2
Wardak, Z.3
-
67
-
-
0037426364
-
The mechanism of Ras GTPase activation by neurofibromin
-
Phillips RA, Hunter JL, Eccleston JF, Webb MR. The mechanism of Ras GTPase activation by neurofibromin. Biochemistry, 42: 3956-3965, 2003.
-
(2003)
Biochemistry
, vol.42
, pp. 3956-3965
-
-
Phillips, R.A.1
Hunter, J.L.2
Eccleston, J.F.3
Webb, M.R.4
-
68
-
-
0343965776
-
Ras signalling. Caught in the act of the switch-on
-
Wittinghofer F. Ras signalling. Caught in the act of the switch-on. Nature, 394: 317, 319-320, 1998.
-
(1998)
Nature
, vol.394
, pp. 317
-
-
Wittinghofer, F.1
-
69
-
-
0031687777
-
Signal transduction via Ras
-
Wittinghofer A. Signal transduction via Ras. Biol Chem, 379: 933-937, 1998.
-
(1998)
Biol Chem
, vol.379
, pp. 933-937
-
-
Wittinghofer, A.1
-
71
-
-
0041737454
-
Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia
-
Epub ahead of print
-
Meshinchi S, Stirewalt DL, Alonzo TA, et al. Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia. Blood 2003 (Epub ahead of print).
-
(2003)
Blood
-
-
Meshinchi, S.1
Stirewalt, D.L.2
Alonzo, T.A.3
-
72
-
-
0026690842
-
Signal transduction through small GTPases - A tale of two GAPs
-
Hall A. Signal transduction through small GTPases - a tale of two GAPs. Cell, 69: 389-391, 1992.
-
(1992)
Cell
, vol.69
, pp. 389-391
-
-
Hall, A.1
-
73
-
-
0026832376
-
Small GTP-binding proteins - A new family of biologic regulators
-
Hall A. Small GTP-binding proteins - a new family of biologic regulators. Am J Respir Cell Mol Biol, 6: 245-246, 1992.
-
(1992)
Am J Respir Cell Mol Biol
, vol.6
, pp. 245-246
-
-
Hall, A.1
-
74
-
-
0029126877
-
Neurofibromatosis type 1 and Ras-mediated signaling: Filling in the GAPs
-
Bernards A. Neurofibromatosis type 1 and Ras-mediated signaling: filling in the GAPs. Biochim Biophys Acta, 1242: 43-59, 1995.
-
(1995)
Biochim Biophys Acta
, vol.1242
, pp. 43-59
-
-
Bernards, A.1
-
75
-
-
0032101134
-
Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines
-
Zhang YY, Vik TA, Ryder JW, et al. Nf1 regulates hematopoietic progenitor cell growth and ras signaling in response to multiple cytokines. J Exp Med, 187: 1893-1902, 1998.
-
(1998)
J Exp Med
, vol.187
, pp. 1893-1902
-
-
Zhang, Y.Y.1
Vik, T.A.2
Ryder, J.W.3
-
76
-
-
0032896457
-
RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)
-
Flotho C, Valcamonica S, Mach-Pascual S, et al. RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML). Leukemia, 13: 32-37, 1999.
-
(1999)
Leukemia
, vol.13
, pp. 32-37
-
-
Flotho, C.1
Valcamonica, S.2
Mach-Pascual, S.3
-
77
-
-
18344385476
-
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
-
Tartaglia M, Mehler EL, Goldberg R, et al. Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nature Genet, 29: 465-468, 2001.
-
(2001)
Nature Genet
, vol.29
, pp. 465-468
-
-
Tartaglia, M.1
Mehler, E.L.2
Goldberg, R.3
-
78
-
-
0030712155
-
Occurrence of myeloproliferative disorder in patients with Noonan syndrome
-
Bader-Meunier B, Tchernia G, Mielot F, et al. Occurrence of myeloproliferative disorder in patients with Noonan syndrome. J Pediatr, 130: 885-889, 1997.
-
(1997)
J Pediatr
, vol.130
, pp. 885-889
-
-
Bader-Meunier, B.1
Tchernia, G.2
Mielot, F.3
-
79
-
-
0033504544
-
Juvenile myelomonocytic leukemia and Noonan syndrome
-
Choong K, Freedman MH, Chitayat D, et al. Juvenile myelomonocytic leukemia and Noonan syndrome. J Pediatr Hematol Oncol, 21: 523-527, 1999.
-
(1999)
J Pediatr Hematol Oncol
, vol.21
, pp. 523-527
-
-
Choong, K.1
Freedman, M.H.2
Chitayat, D.3
-
81
-
-
0036900571
-
Transient abnormal myelopoiesis in Noonan syndrome
-
Ferraris S, Lanza C, Barisone E, et al. Transient abnormal myelopoiesis in Noonan syndrome. J Pediatr Hematol Oncol, 24: 763-764, 2002.
-
(2002)
J Pediatr Hematol Oncol
, vol.24
, pp. 763-764
-
-
Ferraris, S.1
Lanza, C.2
Barisone, E.3
-
82
-
-
0038278866
-
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
-
Tartaglia M, Niemeyer CM, Fragale A, et al. Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nature Genet, 34: 148-150, 2003.
-
(2003)
Nature Genet
, vol.34
, pp. 148-150
-
-
Tartaglia, M.1
Niemeyer, C.M.2
Fragale, A.3
-
83
-
-
0032858394
-
Regulation of megakaryocytopoiesis and platelet production by tyrosine kinases and tyrosine phosphatases
-
Avraham H, Price DJ. Regulation of megakaryocytopoiesis and platelet production by tyrosine kinases and tyrosine phosphatases. Methods, 17: 250-264, 1999.
-
(1999)
Methods
, vol.17
, pp. 250-264
-
-
Avraham, H.1
Price, D.J.2
-
84
-
-
0141567655
-
A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis
-
Epub ahead of print
-
Chan RJ, Johnson SA, Li Y, et al. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood 2003 (Epub ahead of print).
-
(2003)
Blood
-
-
Chan, R.J.1
Johnson, S.A.2
Li, Y.3
-
85
-
-
0035865690
-
Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development
-
Qu CK, Nguyen S, Chen J, Feng GS. Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development. Blood, 97: 911-914, 2001.
-
(2001)
Blood
, vol.97
, pp. 911-914
-
-
Qu, C.K.1
Nguyen, S.2
Chen, J.3
Feng, G.S.4
-
87
-
-
0030797548
-
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development
-
Qu CK, Shi ZQ, Shen R, et al. A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development. Mol Cell Biol, 17: 5499-5507, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5499-5507
-
-
Qu, C.K.1
Shi, Z.Q.2
Shen, R.3
-
88
-
-
0034651043
-
Inhibition of juvenile myelomonocytic leukemia cell growth in vitro by farnesyltransferase inhibitors
-
Emanuel PD, Snyder RC, Wiley T, et al. Inhibition of juvenile myelomonocytic leukemia cell growth in vitro by farnesyltransferase inhibitors. Blood, 95: 639-645, 2000.
-
(2000)
Blood
, vol.95
, pp. 639-645
-
-
Emanuel, P.D.1
Snyder, R.C.2
Wiley, T.3
-
89
-
-
0032400865
-
Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia
-
Frankel AE, Lilly M, Kreitman R, et al. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia. Blood, 92: 4279-4286, 1998.
-
(1998)
Blood
, vol.92
, pp. 4279-4286
-
-
Frankel, A.E.1
Lilly, M.2
Kreitman, R.3
-
90
-
-
0036624790
-
Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
-
Iversen PO, Emanuel PD, Sioud M. Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth. Blood, 99: 4147-4153, 2002.
-
(2002)
Blood
, vol.99
, pp. 4147-4153
-
-
Iversen, P.O.1
Emanuel, P.D.2
Sioud, M.3
-
92
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland DG and Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood, 100: 1532-1542, 2002.
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
|