Electrophysiological Properties of Inhibitory Junction Potential in Murine Lower Oesophageal Sphincter

Journal of Smooth Muscle Research

Volumn 39, Issue 5, 2003, Pages 119-133

  Imaeda, Kenro ^a   Cunnane, Thomas C ^b  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Apamin; ATP; Hyperpolarisation; Inhibitory junction potential; Lower oesophageal sphincter; Mouse; Nitric oxide; Smooth muscle

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ADENOSINE TRIPHOSPHATE; APAMIN; ATROPINE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHARYBDOTOXIN; GLIBENCLAMIDE; GUANETHIDINE; IBERIOTOXIN; KT 5823; N(G) NITROARGININE METHYL ESTER; NIFEDIPINE; POTASSIUM CHANNEL; PURINE P2 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID;

ARTICLE; ELECTROPHYSIOLOGY; EXCITATORY JUNCTION POTENTIAL; HYPERPOLARIZATION; LOWER ESOPHAGUS SPHINCTER; MICROELECTRODE; MUSCLE RELAXATION; SMOOTH MUSCLE;

ANIMALS; ELECTROPHYSIOLOGY; ESOPHAGOGASTRIC JUNCTION; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; NEURAL INHIBITION; NEUROMUSCULAR JUNCTION; NEUROTRANSMITTER AGENTS; POTASSIUM CHANNEL BLOCKERS;

EID: 0346363163     PISSN: 09168737     EISSN: None     Source Type: Journal    
DOI: 10.1540/jsmr.39.119     Document Type: Article

References (26)

1. Allescher, H.D., Berezin, I., Jury, J. and Daniel, E.E. (1988). Characteristics of canine lower esophageal sphincter: a new electrophysiological tool. Am. J. Physiol. 255: G441-G453.
2. Bolton, T.B. and Large, W.A. (1986). Are junction potentials essential? Dual mechanism of smooth muscle cell activation by transmitter released from autonomic nerves. Q. J. Exp. Physiol. 71: 1-28.
3. Conklin, J.L., Du, C., Murray, J.A. and Bates, J.N. (1993). Characterization and mediation of inhibitory junction potentials from opossum lower esophageal sphincter. Gastroenterol. 104: 1439-1444.
4. Cornfield, D.N., Reeve, H.L., Tolarova, S., Weir, E.K. and Archer, S. (1996). Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel. Proc. Natl. Acad. Sci. USA 93: 8089-8094.
5. Crist, J.R., He, X.D. and Goyal, R.K. (1992). Both ATP and the peptide VIP are inhibitory neurotransmitters in guinea-pig ileum circular muscle. J. Physiol. (Lond.) 447: 119-131.
6. Daniel, E.E., Jager, L.P. and Jury, J. (1989). Vasoactive intestinal polypeptide and non-adrenergic, non-cholinergic inhibition in lower oesophageal sphincter of opossum. Br. J. Pharmacol. 96: 746-752.
7. De Man, J.G., Pelckmans, P.A., Boeckxstaens, G.E., Bult, H., Oosterbosch, L., Herman, A.G. and Van Maercke, Y.M. (1991). The role of nitric oxide in inhibitory non-adrenergic non-cholinergic neurotransmission in the canine lower oesophageal sphincter. Br. J. Pharmacol. 103: 1092-1096.
8. Garthwaite, J., Southam, E., Boulton, C.L., Nielsen, E.B., Schmidt, K. and Mayer, B. (1995). Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol. 48: 184-188.
9. . redox form of nitric oxide as nitrergic inhibitory neurotransmitter in gut. Am. J. Physiol. 275: G1185-G1192.
10. Goyal, R.K. and Paterson, W.G. (1989). Esophageal motility. In: Handbook of Physiology, The Gastrointestinal System, ed. by J.D. Wood, Waverly Press, Bethesda, Vol 1, pp. 865-908.
11. Hoyle, C.H.V. and Burnstock, G. (1989). Neuromuscular transmission in the gastrointestinal tract. In: Handbook of Physiology, The Gastrointestinal System, ed. by J.D. Wood, Waverly Press, Bethesda, Vol 1, pp. 435-464.
12. Imaeda, K., Joh, T., Yamamoto, Y., Itoh, M. and Suzuki, H. (1998). Properties of inhibitory junctional transmission in smooth muscle of the guinea pig lower esophageal sphincter. Jpn. J. Physiol. 48: 457-465.
13. Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murakata, C., Sato, A. and Kaneko, M. (1987). K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem. Biophys. Res. Commun. 142: 436-440.
14. Kim, C.D., Goyal, R.K. and Mashimo, H. (1999). Neuronal NOS provides nitrergic inhibitory neurotransmitter in mouse lower esophageal sphincter. Am. J. Physiol. 277: G280-G284.
15. + channels activated by ATP in murine colonic smooth muscle. Am. J. Physiol. 273: C2010-C2021.
16. 2 purinoceptor-mediated responses. Eur. J. Pharmacol. 217: 217-219.
17. Moncada, S., Palmer, R.M. and Higgs, E.A. (1991). Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142.
18. Murphy, M.E. and Brayden, J.E. (1995). Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels. J. Physiol. (Lond.) 486: 47-58.
19. Ny, L., Alm, P., Larsson, B., Ekstrom, P. and Andersson, K.E. (1995). Nitric oxide pathway in cat esophagus: localization of nitric oxide synthase and functional effects. Am. J. Physiol. 268: G59-G70.
20. 2+ sparks is involved in regulation of arterial diameter by cyclic nucleotides. Am. J. Physiol. 274: C1346-C1355.
21. Rae, M.G. and Muir, T.C. (1996). Neuronal mediators of inhibitory junction potentials and relaxation in the guinea-pig internal anal sphincter. J. Physiol. (Lond.) 493: 517-527.
22. Robertson, B.E., Schubert, R., Hescheler, J. and Nelson, M.T. (1993). cGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells. Am. J. Physiol. 265: C299-C303.
23. Selemidis, S., Ziogas, J. and Cocks, T.M. (1998). Apamin- and nitric oxide-sensitive biphasic non-adrenergic non-cholinergic inhibitory junction potentials in the rat anococcygeus muscle. J. Physiol. (Lond.) 513: 835-844.
24. Ward, S.M., Morris, G., Reese, L., Wang, X.Y. and Sanders, K.M. (1998). Interstitial cells of Cajal mediate enteric inhibitory neurotransmission in the lower esophageal and pyloric sphincters. Gastroenterol. 115: 314-329.
25. Xue, L., Farrugia, G., Sarr, M.G. and Szurszewski, J.H. (1999). ATP is a mediator of the fast inhibitory junction potential in human jejunal circular smooth muscle. Am. J. Physiol. 276: G1373-G1379.
26. Yuan, S., Costa, M. and Brookes, S.J. (1998). Neuronal pathways and transmission to the lower esophageal sphincter of the guinea Pig. Gastroenterol. 115: 661-671.