Fluorescence immunohistochemistry and confocal scanning laser microscopy: A protocol for studies of joint innervation

Acta Orthopaedica Scandinavica

Volumn 74, Issue 6, 2003, Pages 689-696

  Jew, Jean Y ^a   Berger, Evelyn J ^b   Berger, Richard A ^b   Lin, Yu Te ^b  

^a UNIVERSITY OF IOWA   (United States)

^b MAYO CLINIC ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CADAVER; CLINICAL PROTOCOL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE; FLUORESCENT LIGHTING; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMAGE QUALITY; IMAGING SYSTEM; IMMUNOHISTOCHEMISTRY; LIGAMENT; LIGHT EXPOSURE; MICROSCOPE; NERVE ENDING; NERVE FIBER; THREE DIMENSIONAL IMAGING; WRIST;

FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; HYDRAZINES; JOINTS; MECHANORECEPTORS; MICROSCOPY, CONFOCAL; NEURONS;

EID: 0346340845     PISSN: 00016470     EISSN: None     Source Type: Journal    
DOI: 10.1080/00016470310018216     Document Type: Article

References (36)

1. Backenköhler U, Strasmann T J, Halata Z. Topography of mechanoreceptors in the shoulder region. A computer-aided 3D reconstruction in the laboratory mouse. Anat Rec 1997; 248: 433-41.
2. Beaman D N, Graziano G P, Glover R A, Wojtys E M, Chang V. Substance P innervation of lumbar spine facet joints. Spine 1993; 18: 1044-9.
3. Berger R A. The anatomy of the ligaments of the wrist and distal radioulnar joint. Clin Orthop 2001; 383: 32-40.
4. Bielchowsky M. Die Silberimpragnation der Axencylinder. Neurol Zbl 1902; 21: 579-84.
5. Bodian D. A new method for staining nerve fibers and nerve endings in mounted paraffin sections. Anat Rec 1936; 65: 89-97.
6. Brakenhoff G J, van der Voort H T M, van Spronsen E A, Nanninga N. Three-dimensional imaging by confocal scanning fluorescence microscopy. J Microsc 1989; 153: 151-9.
7. Brodin L, Ericsson M, Mossberg K, Hokfelt T, Ohta Y, Grillner S. Three-dimensional reconstruction of transmitter-identified central neurons by "en bloc" immunofluorescence histochemistry and confocal scanning microscopy. Exp Brain Res 1988; 73: 441-6.
8. Cajal S R. 1911. Histologie du système nerveux de l'homme et des vertebres, Paris: Maloine; Edition Francaise Revue: Tome I, 1952; Madrid: Consejo Superior de Investigaciones Cientificas.
9. De Avila G A, O'Connor B L, Visco D M, Sisk T D. The mechanoreceptor innervation of the human fibular collateral ligament. J Anat 1989; 162: 1-7.
10. Freeman M A, Wyke B. The innervation of the ankle joint. An anatomical and histological study in the cat. Acta Anat 1967; 68: 321-33.
11. Gairns F. Modified gold chloride method for the demonstration of nerve endings. Q J Microsc Sci 1930; 74: 151-5.
12. Georgoulis A D, Pappa L, Moebius U, Malamou-Mitsi V, Pappa S, Papageorgiou C O, et al. The presence of proprioceptive mechanoreceptors in the remnants of the ruptured ACL as a possible source of re-innervation of the ACL autograft. Knee Surg Sports Traumatol Arthrose 2001; 9: 364-8.
13. Goertzen M, Gruber J, Dellmann A, Clahsen H, Schulitz K-P. Neurohistological findings after experimental anterior cruciate ligament allograft transplantation. Arch Orthop Trauma Surg 1992; 111: 126-9.
14. Golgi C. Sulla struttura della sostanza grigia del cervello. Gaz Med Ital Lombardia 1873; 6: 244-6.
15. Hirasawa Y, Okajima S, Ohta M, Tokioka T. Nerve distribution to the human knee joint: anatomical and immunohistochemical study. Int Orthop 2000; 24: 1-4.
16. Hsu S M, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981; 29: 577-80.
17. Hukkanen M, Konttinen Y T, Rees R G, Santavirta S, Terebghi G, Polak J M. Distribution of nerve endings and sensory neuropeptides in rat synovium, meniscus and bone. Int J Tiss React 1992; 14: 1-10.
18. Jang Y C, Isik F F, Gibran N S. Nerve distribution in hemangiomas depends on the proliferative state of the microvasculature. J Surg Res 2000; 93: 144-8.
19. Jew J Y, Fink C A, Williams T H. Tyrosine hydrolase-and nitric oxide synthase-immunoreactive nerve fibers in mitral valve of young adult and aged Fischer 344 rats. J Auton Nerv Syst 1996; 58: 35-43.
20. Jozsa L, Balint J, Kannus P, Jarvinen M, Lehto M. Mechanoreceptors in human myotendinous junction. Muscle Nerve 1993; 16: 453-7.
21. Kennedy J C, Weinberg H W, Wilson A S. The anatomy and function of the anterior cruciate ligament. J Bone Joint Surg (Am) 1974; 56: 223-35.
22. Kennedy J C, Alexander I J, Hayes K C. Nerve supply of the human knee and its functional importance. Am J Sports Med 1982; 10: 329-35.
23. Koch B, Kurriger G, Brand R A. Characterisation of the neurosensory elements of the feline cranial cruciate ligament. J Anat 1995; 187: 353-9.
24. Korkala O, Grönblad M, Liesi P, Karaharju E. Immunohistochemical demonstration of nociceptors in the ligamentous structures of the lumbar spine. Spine 1985; 10: 156-7.
25. McLain R F, Pickar J G. Mechanoreceptor endings in human thoracic and lumbar facet joints. Spine 1998; 23: 168-73.
26. Palmgren T, Grönblad M, Virri J, Kappa E, Karaharju E. An immunohistochemical study of nerve structures in the annulus fibrosus of human normal lumbar intervertebral discs. Spine 1999; 24: 2075-9.
27. Petrie S, Collins J, Solomonow M, Wink C, Chuinard R. Mechanoreceptors in the palmar wrist ligaments. J Bone Joint Surg (Br) 1997; 79: 494-6.
28. Petrie S, Collins J G, Solomonow M, Wink C, Chuinard R, D'Ambrosia R. Mechanoreceptors in the human elbow ligaments. J Hand Surg 1998; 23A: 512-8.
29. Raunest J, Sager M, Burgener E. Proprioception of the cruciate ligaments: Receptor mapping in an animal model. Arch Orthop Trauma Surg 1998; 118: 159-63.
30. Rhalmi S, Yahia L H, Newman N, Isler M. Immunohistochemical study of nerves in lumbar spine ligaments. Spine 1993; 18: 264-7.
31. Roberts S, Eisenstein S M, Menage J, Evans E H, Ashton I K. Mechanoreceptors in intervertebral discs. Morphology, distribution, and neuropeptides. Spine 1995; 20: 2645-51.
32. Sathian K, Devanandan M S. Receptors of the metacarpophalangeal joints: a histological study in the bonnet monkey and man. J Anat 1983; 137: 601-3.
33. Shotton D, White N. Confocal scanning microscopy: three-dimensional biological imaging. Trends Biochem Sci 1989; 14: 435-9.
34. Sternberger L A. The unlabeled antibody (PAP) method. J Histochem Cytochem 1979; 27: 1657-9.
35. Vilensky J A, O'Connor B L, Fortin J D, Merkel G J, Jimenez A M, Scofield B A, Kleiner J B. Histologic analysis of neural elements in the human sacroiliac joint. Spine 2002; 27: 1202-7.
36. Zimny M L. Mechanoreceptors in articular tissues. Am J Anat 1988; 182: 16-32.