Management of depression in long-term care of patients with Alzheimer's disease

Journal of the American Medical Directors Association

Volumn 4, Issue 6 SUPPL., 2003, Pages

  Peskind, Elaine R ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; FLUOXETINE; IMIPRAMINE; MOCLOBEMIDE; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; PLACEBO; SEROTONIN AGONIST; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; SODIUM; TRICYCLIC ANTIDEPRESSANT AGENT;

ALZHEIMER DISEASE; ANOREXIA; ANTICHOLINERGIC EFFECT; ARTICLE; BEHAVIOR THERAPY; CAREGIVER; CLINICAL TRIAL; COGNITIVE DEFECT; COMORBIDITY; CONSTIPATION; DEPRESSION; DIARRHEA; DISABILITY; DRUG EFFICACY; DRUG SAFETY; ELDERLY CARE; ELECTROCONVULSIVE THERAPY; EXTRAPYRAMIDAL SYMPTOM; HEART DISEASE; HUMAN; HYPONATREMIA; LONG TERM CARE; MORBIDITY; MORTALITY; NAUSEA; ORTHOSTATIC HYPOTENSION; PATIENT CARE; PSYCHOPHARMACOTHERAPY; PSYCHOSIS; QUALITY OF LIFE; RISK FACTOR; SIDE EFFECT; SYMPTOM; URINE RETENTION; WEIGHT REDUCTION;

EID: 0346269306     PISSN: 15258610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-8610(04)70405-3     Document Type: Article

References (34)

1. Katz IR, Lesher E, Kleban M, et al. Clinical features of depression in the nursing home. Int Psychogeriatr 1989;1:5-15.
2. Burns BJ, Larson DB, Goldstrom ID, et al. Mental disorder among nursing home patients: Preliminary findings from the National Nursing Home Survey pretest. Int J Geriatr Psychiatry 1988;3:27-35.
3. Blazer D. The epidemiology of mental illness in late life. In: Busse EW, Blazer DG, eds. Handbook of Geriatric Psychiatry. New York: Van Nostrand Reinhold Co; 1980.
4. Rovner BW, German PS, Brant LJ, et al. Depression and mortality in nursing homes. JAMA 1991;265:993-996.
5. Rohde K, Peskind ER, Raskind MA. Suicide in two patients with Alzheimer's disease. J Am Geriatr Soc 1995;43:187-189.
6. Alexopoulos GS, Abrams RC, Young RC, et al. Cornell scale for depression in dementia. Biol Psychiatry 1988;24:271-284.
7. Caine ED. Pseudodementia. Current concepts and future directions. Arch Gen Psychiatry 1981;38:1359-1364.
8. Reifler BV, Larson E, Teri L, et al. Dementia of the Alzheimer's type and depression. J Am Geriatr Soc 1986;34:855-859.
9. Alexopoulos GS, Myers BS, Young RC, et al. The course of geriatric depression with 'reversible dementia': A controlled study. Am J Psychiatry 1993;150:1693-1699.
10. Kral VA, Emery OB. Long-term follow-up of depressive pseudodementia of the aged. Can J Psychiatry 1989;34:445-446.
11. Geerlings MI, Schoevers RA, Beekman AT, et al. Depression and risk of cognitive decline and Alzheimer's disease. Results of two prospective community-based studies in the Netherlands. Br J Psychiatry 2000;176: 568-575.
12. Ritchie K, Gilham C, Ledesert B, et al. Depressive illness, depressive symptomatology and regional cerebral blood flow in elderly people with sub-clinical cognitive impairment. Age Ageing 1999;28:385-391.
13. Yaffe K, Blackwell T, Gore R, et al. Depressive symptoms and cognitive decline in nondemented elderly women: a prospective study. Arch Gen Psychiatry 1999;56:425-430.
14. Bassuk SS, Berkman LF, Wypij D. Depressive symptomatology and incident cognitive decline in an elderly community sample. Arch Gen Psychiatry 1998;55:1073-1081.
15. Zubenko GS, Rifai AH, Mulsant BH, et al. Association of premorbid history of major depression with the depressive syndrome of Alzheimer's disease. Am J Geriatr Psychiatry 1996;4:85-90.
16. van Ojen R, Hooijer C, Bezmer D, et al. Late-life depressive disorder in the community. I. The relationship between MMSE score and depression in subjects with and without psychiatric history. Br J Psychiatry 1995; 166:311-315.
17. Green RC, Cupples A, Kurz A, et al. Depression as a risk factor for Alzheimer disease. Arch Neurol 2003;60:753-759.
18. Devanand DP, Sano M, Tang MX, et al. Depressed mood and the incidence of Alzheimer's disease in the elderly living in the community. Arch Gen Psychiatry 1996;53:175-182.
19. Dufouil C, Fuhrer R, Dartigues JF, Alperovitch A. Longitudinal analysis of the association between depressive symptomatology and cognitive deterioration. Ann J Epidemiol 1996;144:634-641.
20. Henderson AS, Korten AE, Jacomb PA, et al. The course of depression in the elderly: A longitudinal community-based study in Australia. Psychol Med 1997;27:119-129.
21. Dobie DJ, Raskind MA. Biology in Geriatric Psychiatry: Diagnostic Implications. In: Tasman A, Goldfinger SM, Kaufman CA, eds. American Psychiatric Press Review of Psychiatry, vol 9. Washington, DC: American Psychiatric Press; 1990.
22. Magariños AM, McEwen BS. Stress-induced atrophy of apical dendrites of hippocampal CA3 neurons: Comparison of stressors. Neuroscience 1995;69:83-88.
23. Sapolsky RM, Krey LC, McEwen BS. Prolonged glucocorticoid exposure reduces hippocampal neuronal number: Implications for aging. J Neurosci 1985;5:1221-1226.
24. Magariños AM, McEwen BS, Flugge G, et al. Chronic psychosocial stress causes apical dendritic atrophy of hippocampal CA3 pyramidal neurons in subordinate tree shrews. J Neurosci 1996;16:3534-3540.
25. Reifler BV, Teri L, Raskind M, et al. Double-blind trial of imipramine in Alzheimer's disease patients with and without depression. Am J Psychiatry 1989;146:45-49.
26. Petracca G, Teson A, Chemerinski E, et al. A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci 1996;8:270-275.
27. Roth M, Mountjoy CQ, Amrein R. Moclobemide in elderly patients with cognitive decline and depression: An international double blind placebo-controlled trial. Br J Psychiatry 1996;168:149-157.
28. Nyth AL, Gottfries CG, Lyby K, et al. A controlled multicenter clinical trial of citalopram and placebo in elderly depressed patients. Acta Psychiatr Scand 1992;86:138-145.
29. Petracca GM, Chemerinski E, Starkstein SE. A double blind, placebo-controlled study of fluoxetine in depressed patients with Alzheimer's disease. Int Psychogeriatr 2001;13:233-240.
30. Magai C, Kennedy G, Cohen CI, et al. A controlled clinical trial of sertraline in the treatment of depression in nursing home patients with late stage Alzheimer's disease. Am J Geriatr Psychiatry 2000;8: 66-74.
31. Lyketsos CG, DelCampo L, Steinberg M, et al. Treating depression in Alzheimer disease: Efficacy and safety of sertraline therapy and the benefits of depression reduction: the DIADS. Arch Gen Psychiatry 2003;60:737-746.
32. Vandel P. Antidepressant drugs in the elderly: Role of cytochrome P450 2D6. World J Biol Psychiatry 2003;4:74-80.
33. Pollock BG. Adverse reactions of antidepressants in elderly patients. J Clin Psychiatry 1999;60(suppl 20):4-8.
34. Teri L, Logsdon RG, Uomoto J, et al. Behavioral treatment of depression in dementia patients: a controlled clinical trial. J Gerontol B Psychol Sci Soc Sci 1997;52:P159-P166.