Diagnostic validity of the Ki-67 labeling index using the MIB-1 monoclonal antibody in the grading of meningiomas

Neurology India

Volumn 51, Issue 3, 2003, Pages 336-340

  Devaprasath, A ^a   Chacko, Geeta ^a  

^a CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Immunohistochemistry; Ki 67; Meningioma; MIB 1; Proliferative index

Indexed keywords

ANTINEOPLASTIC AGENT; KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67;

ADOLESCENT; ADULT; AGED; ANAPLASTIC CARCINOMA; ARTICLE; ATYPICAL MENINGIOMA; BENIGN TUMOR; CANCER CLASSIFICATION; CANCER GRADING; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL ARTICLE; CORRELATION ANALYSIS; FEMALE; FISHER EXACT TEST; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LABELING INDEX; MALE; MALIGNANT MENINGIOMA; MENINGIOMA; MITOSIS RATE; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS; VALIDATION PROCESS; WORLD HEALTH ORGANIZATION;

ADOLESCENT; ADULT; AGED; ANTIBODIES, ANTINUCLEAR; ANTIBODIES, MONOCLONAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; MALE; MENINGEAL NEOPLASMS; MENINGIOMA; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES;

EID: 0346252593     PISSN: 00283886     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Donald A. Smith, David W. Cahill. The biology of meningiomas. Neurosurg Clin N Am 1994;5:201-15.
2. Ohta M, Iwaki T, Kitamoto T, Takeshita I, Tateishi J, Fukui M, MIB-1 staining index and scoring of histological features in meningioma. Cancer 1994;74:3176-89.
3. Louis DN, Scheithauer BW, Budka H, Von Deimling A, Kepes JJ. Meningiomas In: Kleihues P, Cavenee WK, editors. Pathology and Genetics. Tumors of the Nervous System: WHO Classification of Tumors. 1st edn. Lyon: IARC Press; 2000. pp. 176-84.
4. Langford LA, Cooksley B, DeMonte F. Comparison of MIB-1 and BRDU proliferation indices in meningiomas. Hum Pathol 1996;27:350-4.
5. Kolles N, Niedermayer I, Schmitt C, Henn W, Feld R, Steudel W. Triple approach for the diagnosis and grading of meningiomas; Histology, morphometery of Ki67/Feulgen staining and cytogenetics. Acta Neurochir Wien 1995;137:174-81.
6. Hopf NJ, Bremm J, Bohl J, Perneczky A. Image analysis of proliferating cells in tumors of the human nervous system: An immunohistological study with monoclonal Antibody Ki67. Neurosurg 1994;35:917-23.
7. Prayson RA. Malignant meningiomas - A clinicopathological study of 23 patients including MIB-1 and p53 immunohistochemistry. Am J Clin Pathol 1996;105:719-26.
8. Abramovich CM, Prayson RA. MIB-1 labeling indices in benign, aggressive and malignant meningiomas: A study of 90 tumors. Hum Pathol 1998;29:1420-7.
9. Abramovich CM, Prayson RA. Histopathologic features and MIB-1 labeling indices in recurrent and nonrecurrent meningiomas. Arch Pathol Lab Med 1999;123:793-800.
10. Perry A, Stafford SL, Scheithauer BW, Suman VJ, Lohse CM. Meningioma Grading - An analysis of histologic parameters. Am J Surg Pathol 1997;21:1455-65.
11. Perry A, Stafford SL, Scheithauer BW, Suman VJ, Lohse CM. The prognostic significance of MIB-1, p53, and DNA flow cytometry in completely resected primary meningiomas. Cancer 1998;82:2262-9.
12. Perry A, Stafford SL, Scheithauer BW, Lohse CM, Wollan PC. "Malignancy" in meningiomas. Cancer 1999;85:2046-56.
13. Norton AJ, Jordon S, Yeomans P. Brief, high temperature denaturation (pressure cooking): A simple and effective method of antigen retrieval for routinely processed tissues. J Pathol 1994;173:371-9.