TraJ-Dependent Escherichia coli K1 Interactions with Professional Phagocytes Are Important for Early Systemic Dissemination of Infection in the Neonatal Rat

Infection and Immunity

Volumn 72, Issue 1, 2004, Pages 478-488

  Hill, Val T ^a   Townsend, Stacy M ^a   Arias, Robyn S ^a,b   Jenabi, Jasmine M ^a   Gomez Gonzalez, Ignacio ^a,b   Shimada, Hiroyuki ^a,b   Badger, Julie L ^a,b,c  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BLOOD; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; ESCHERICHIA COLI; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; INFLAMMATION; INTERNALIZATION; INTESTINE; LIVER; LYMPHOID TISSUE; MACROPHAGE; MENINGITIS; NEWBORN; NEWBORN SEPSIS; NONHUMAN; NORMAL HUMAN; PHAGOCYTE; PRIORITY JOURNAL; RAT; SPLEEN; SYSTEMIC DISEASE; TRAJ GENE;

ANIMALS; ANIMALS, NEWBORN; BACTERIAL OUTER MEMBRANE PROTEINS; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; HUMANS; LIVER; MACROPHAGES, PERITONEAL; NEUTROPHIL INFILTRATION; PHAGOCYTES; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN; U937 CELLS; VIRULENCE;

EID: 0346251027     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.1.478-488.2004     Document Type: Article

References (45)

1. Aderem, A., and D. M. Underhill. 1999. Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 17:593-623.
2. Aguero, M. E., G. de la Fuente, E. Vivaldi, and F. Cabello. 1989. ColV increases the virulence of Eschirichia coli K1 strains in animal models of neonatal meningitis and urinary infection. Med. Microbiol. Immunol. 178:211-216.
3. Allen, L. A. 2001. The role of the neutrophil and phagocytosis in infection caused by Helicobacter pylori. Curr. Opin. Infect. Dis. 14:273-277.
4. Badger, J. L., and K. S. Kim. 1998. Environmental growth conditions influence the ability of Escherichia coli K1 to invade brain microvascular endothelial cells and confer serum resistance. Infect. Immun. 66:5692-5697.
5. Badger, J. L., C. A. Wass, and K. S. Kim. 2000. Identification of Escherichia coli K1 genes contributing to human brain microvascular endothelial cell invasion by differential fluorescence induction. Mol. Microbiol. 36(1):174-182.
6. Badger, J. L., C. A. Wass, S. J. Weissman, and K. S. Kim. 2000. Application of signature-tagged mutagenesis for identification of Escherichia coli K1 genes that contribute to invasion of human brain microvascular endothelial cells. Infect. Immun. 68:5056-5061.
7. Bloch, C. A., and P. E. Orndorff. 1990. Impaired colonization by and full invasiveness of Escherichia coli K1 bearing a site-directed mutation in the type 1 pilin gene. Infect. Immun. 58:275-278.
8. Bloch, C. A., B. A. Stocker, and P. E. Orndorff. 1992. A key role for type 1 pili in enterobacterial communicability. Mol. Microbiol. 6:697-701.
9. Bloch, C. A., G. M. Thorne, and F. M. Ausubel. 1989. General method for site-directed mutagenesis in Escherichia coli O18ac:K1:H7: deletion of the inducible superoxide dismutase gene, sodA, does not diminish bacteremia in neonatal rats. Infect. Immun. 57:2141-2148.
10. Bortolussi, R., P. Ferrieri, B. Björkstén, and P. G. Quie. 1979. Capsular K1 polysaccharide of Escherichia coli: relationship to virulence in newborn rats and resistance to phagocytosis. Infect. Immun. 25:293-298.
11. Bortolussi, R., P. Ferrieri, and L. W. Wannamaker. 1978. Dynamics of Escherichia coli infection and meningitis in infant rats. Infect. Immun. 22:480-485.
12. Cross, A. S., K. S. Kim, D. C. Wright, J. C. Sadoff, and P. Gemski. 1986. Role of lipopolysaccharide and capsule in the serum resistance of bacteremic strains of Escherichia coli. J. Infect. Dis. 154:497-503.
13. Denholm, E. M., and G. P. Stankus. 1995. Differential effects of two fluorescent probes on macrophage migration as assessed by manual and automated methods. Cytometry 19:366-369.
14. Feigin, R. D. 1977. Bacterial meningitis in the newborn infant. Clin. Perinatol. 4:103-116.
15. Frost, L. S., K. Ippen-lhler, and R. A. Skurray. 1994. Analysis of the sequence and gene products of the transfer region of the F sex factor. Microbiol. Rev. 58:162-210.
16. Glode, M. P., A. Sutton, E. R. Moxon, and J. B. Robbins. 1977. Pathogenesis of neonatal Escherichia coli meningitis: induction of bacteremia and meningitis in infant rats fed E. coli K1. Infect. Immun. 16:75-80.
17. Gonzalez, M. D., C. A. Lichtensteiger, and E. R. Vimr. 2001. Adaptation of signature-tagged mutagenesis to Escherichia coli K1 and the infant-rat model of invasive disease. FEMS Microbiol. Lett. 198:125-128.
18. Guerina, N. G., T. W. Kessler, V. J. Guerina, M. R. Neutra, H. W. Clegg, S. Langermann, F. A. Scannapieco, and D. A. Goldmann. 1983. The role of pili and capsule in the pathogenesis of neonatal infection with Escherichia coli K1. J. Infect. Dis. 148:395-405.
19. Hoffman, J. A., C. Wass, M. F. Stins, and K. S. Kim. 1999. The capsule supports survival but not traversal of Escherichia coli K1 across the blood-brain barrier. Infect. Immun. 67:3566-3570.
20. Huang, S.-H., C. Wass, Q. Fu, N. V. Prasadarao, M. Stins, and K. S. Kim. 1995. Escherichia coli invasion of brain microvascular endothelial cells in vitro and in vivo: molecular cloning and characterization of invasion gene ibe10. Infect. Immun. 63:4470-4475.
21. Kasper, D. L., J. L. Winkelhake, W. D. Zollinger, B. L. Brandt, and M. S. Artenstein. 1973. Immunochemical similarity between polysaccharide antigens of Escherichia coli 07: K1(L):NM and group B Neisseria meningitidis. J. Immunol. 110:262-268.
22. Kim, K. S., H. Itabashi, P. Gemski, J. Sadoff, R. L. Warren, and A. S. Cross. 1992. The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat. J. Clin. Investig. 90:897-905.
23. Lepay, D. A., C. F. Nathan, R. M. Steinman, H. W. Murray, and Z. A. Cohn. 1985. Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates. J. Exp. Med. 161:1079-1096.
24. Leying, H., S. Suerbaum, H.-P. Kroll, D. Stahl, and W. Opferkuch. 1990. The capsular polysaccharide is a major determinant of serum resistance in K-1-positive blood culture isolates of Escherichia coli. Infect. Immun. 58:222-227.
25. Martindale, J., D. Stroud, E. R. Moxon, and C. M. Tang. 2000. Genetic analysis of Escherichia coli K1 gastrointestinal colonization. Mol. Microbiol. 37:1293-1305.
26. McCracken, G. H., Jr., L. D. Sarff, M. P. Glode, S. G. Mize, M. S. Schiffer, J. B. Robbins, E. C. Gotschlich, I. Orskov, and F. Orskov. 1974. Relation between Escherichia coli K1 capsular polysaccharide antigen and clinical outcome in neonatal meningitis. Lancet ii:246-250.
27. Moxon, E. R., M. P. Glode, A. Sutton, and J. B. Robbins. 1977. The infant rat as a model of bacterial meningitis. J. Infect. Dis. 136(Suppl.):S186-S190.
28. Pluschke, G., J. Mayden, M. Achtman, and R. P. Levine. 1983. Role of the capsule and the O antigen in resistance of O18:K1 Escherichia coli to complement-mediated killing. Infect. Immun. 42:907-913.
29. Pluschke, G., A. Mercer, B. Kuseæek, A. Pohl, and M. Achtman. 1983. Induction of bacteremia in newborn rats by Escherichia coli K1 is correlated with only certain O (lipopolysaccharide) antigen types. Infect. Immun. 39:599-608.
30. Prasadarao, N. V., C. A. Wass, J. N. Weiser, M. F. Stins, S.-H. Huang, and K. S. Kim. 1996. Outer membrane protein A of Escherichia coli contributes to invasion of brain microvascular endothelial cells. Infect. Immun. 64:146-153.
31. Reed, M. J., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
32. Robbins, J. B., G. H. McCracken, Jr., E. C. Gotschlich, F. Orskov, I. Orskov, and L. A. Hanson. 1974. Escherichia coli K1 capsular polysaccharide associated with neonatal meningitis. N. Engl. J. Med. 290:1216-1220.
33. Sarff, L. D., G. H. McCracken, M. S. Schiffer, M. P. Glode, J. B. Robbins, I. Orskov, and F. Orskov. 1975. Epidemiology of Escherichia coli K1 in healthy and diseased newborns. Lancet i:1099-1104.
34. Scannapieco, F. A., N. G. Guerina, and D. A. Goldmann. 1982. Comparison of virulence and colonizing capacity of Escherichia coli K1 and non-K1 strains in neonatal rats. Infect. Immun. 37:830-832.
35. Siegel, J. D., and G. H. McCracken, Jr. 1981. Sepsis neonatorum. N. Engl. J. Med. 304:642-647.
36. Smith, H. W., and M. B. Huggins. 1980. The association of the O18, K1 and H7 antigens and the ColV plasmid of a strain of Escherichia coli with its virulence and immunogenicity. J. Gen. Microbiol. 121:387-400.
37. Stevens, P., S. N. Huang, W. D. Welch, and L. S. Young. 1978. Restricted complement activation by Escherichia coli with the K-1 capsular serotype: a possible role in pathogenicity. J. Immunol. 121:2174-2180.
38. Taylor, P. W., and H. P. Kroll. 1983. Killing of an encapsulated strain of Escherichia coli by human serum. Infect. Immun. 39:122-131.
39. Tunkel, A. R., and W. M. Scheld. 1993. Pathogenesis and pathophysiology of bacterial meningitis. Clin. Microbiol. Rev. 6:118-136.
40. Tunkel, A. R., B. Wispelwey, and W. M. Scheld. 1990. Pathogenesis and pathophysiology of meningitis. Infect. Dis. Clin. North Am. 4:555-581.
41. Underhill, D. M., and A. Ozinsky. 2002. Phagocytosis of microbes: complexity in action. Annu. Rev. Immunol. 20:825-852.
42. van Biesen, T., F. Soderbom, E. G. Wagner, and L. S. Frost. 1993. Structural and functional analyses of the FinP antisense RNA regulatory system of the F conjugative plasmid. Mol. Microbiol. 10:35-43.
43. Watarai, M., I. Derre, J. Kirby, J. D. Growney, W. F. Dietrich, and R. R. Isberg. 2001. Legionella pneumophila is internalized by a macropinocytotic uptake pathway controlled by the Dot/Icm system and the mouse Lgnl locus. J. Exp. Med. 194:1081-1096.
44. Weiser, J. N., and E. C. Gotschlich. 1991. Outer membrane protein A (OmpA) contributes to serum resistance and pathogenicity of Escherichia coli K-1. Infect. Immun. 59:2252-2258.
45. Wilson, M., R. Seymour, and B. Henderson. 1998. Bacterial perturbation of cytokine networks. Infect. Immun. 66:2401-2409.