The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: The absence of two inter-subunit salt bridges as a reason for enzyme instability

Molecular and Biochemical Parasitology

Volumn 133, Issue 2, 2004, Pages 197-207

  Esteve, Mariana Igoillo ^a   Cazzulo, Juan José ^a  

^a Univ Nac de Gen S Martin CONICET   (Argentina)

Author keywords

6 Phosphogluconate dehydrogenase; Pentose phosphate pathway; Salt bridges in dimeric structure; Site directed mutagenesis; Trypanosoma cruzi

Indexed keywords

GLUCONIC ACID; PHOSPHOGLUCONATE DEHYDROGENASE; PROTOZOAL PROTEIN; RECOMBINANT ENZYME;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; DNA TEMPLATE; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE SEQUENCE; GENETIC RECOMBINATION; GENOME; HAPLOIDY; KINETICS; MOLECULAR CLONING; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOUTHERN BLOTTING; SPECIES COMPARISON; STATISTICAL SIGNIFICANCE; STRUCTURAL HOMOLOGY; TRYPANOSOMA CRUZI;

ESCHERICHIA COLI; MAMMALIA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

EID: 0346157320     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2003.10.007     Document Type: Article

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