Pharmacology and Toxicology of Major Constituents of Marijuana - On the Metabolic Activation of Cannabinoids and Its Mechanism

Journal of Toxicology - Toxin Reviews

Volumn 22, Issue 4, 2003, Pages 577-589

  Yamamoto, Ikuo ^a   Watanabe, Kazuhito ^b   Matsunaga, Tamihide ^c   Kimura, Toshiyuki ^b   Funahashi, Tatsuya ^b   Yoshimura, Hidetoshi ^d  

^a KYUSHU UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^b HOKURIKU UNIVERSITY   (Japan)

^c SHINSHU UNIVERSITY HOSPITAL   (Japan)

^d NAKAMURA GAKUEN UNIVERSITY   (Japan)

Author keywords

Cannabidiol; Cannabinol; Cytochrome P450; Metabolic activation; Microsomal aldehyde oxygenase; Receptor binding; Tetrahydrocannabinol; Tolerance development

Indexed keywords

11 HYDROXYCANNABIDIOL; 11 HYDROXYTETRAHYDROCANNABINOL; 11 OXO DELTA8 TETRAHYDROCANNABINOL; 3 PENTYL 6,7,7A,8,9,11A HEXAHYDRO 1,7 DIHYDROXY 7,10 DIMETHYLDIBENZO[B,D]OXEPIN; 3' HYDROXY DELTA9 TETRAHYDROCANNABINOL; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 6 HYDROXYMETHYL DELTA9 TETRAHYDROCANNABINOL; 7 OXO DELTA8 TETRAHYDROCANNABINOL; 8BETA,9BETA EPOXYHEXAHYDROCANNABINOL; 9 EPOXYCANNABIDIOL; 9ALPHA,10ALPHA EPOXYHEXAHYDROCANNABINOL; ALDEHYDE OXIDASE; CANNABIDIOL; CANNABINOID; CANNABINOL; CANNABIS; CYTOCHROME P450 2C11; CYTOCHROME P450 2C29; CYTOCHROME P450 2C37; CYTOCHROME P450 2C6; CYTOCHROME P450 2C9; CYTOCHROME P450 ISOENZYME; DRUG METABOLITE; PENTOBARBITAL; TETRAHYDROCANNABINOL DERIVATIVE; UNCLASSIFIED DRUG;

BRAIN CORTEX; CATALEPSY; CONFERENCE PAPER; DRUG ACTIVATION; DRUG HYDROXYLATION; DRUG MECHANISM; DRUG METABOLISM; DRUG OXIDATION; DRUG RECEPTOR BINDING; DRUG TOLERANCE; DRUG TRANSFORMATION; HUMAN; HYPOTHERMIA; LIVER MICROSOME; NONHUMAN;

ANIMALIA; BOVINAE; CANNABIS; CANNABIS SATIVA; MAMMALIA;

EID: 0346122937     PISSN: 07313837     EISSN: None     Source Type: Journal    
DOI: 10.1081/TXR-120026915     Document Type: Conference Paper

References (15)

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