Use of surface plasmon resonance biosensor technology as a possible alternative to detect differences in binding of enantiomeric drug compounds to immobilized albumins

Biosensors and Bioelectronics

Volumn 18, Issue 4, 2003, Pages 399-404

  Ahmad, Ateeq ^a,b   Ramakrishnan, Anand ^a   McLean, Matthew A ^a   Breau, Alan P ^a  

^a PFIZER INC   (United States)

^b NeoPharm Inc   (United States)

Author keywords

Affinity values; Biacore 3000 biosensor; Enantiomers; Immobilized albumins; Normalized responses

Indexed keywords

DRUG PRODUCTS; LABELS; PARAMETER ESTIMATION; PROTEINS; STATISTICAL METHODS; SURFACE PLASMON RESONANCE;

AFFINITY VALUES; BIACORE 3000 BIOSENSOR; ENANTIOMERS; IMMOBILIZED ALBUMINS; NORMALIZED VALUES;

BIOSENSORS;

ALBUMIN; WARFARIN; DRUG; SERUM ALBUMIN;

ARTICLE; BIOSENSOR; ENANTIOMER; MOLECULAR INTERACTION; PROTEIN BINDING; REPRODUCIBILITY; SURFACE PLASMON RESONANCE; VALIDATION PROCESS; ANIMAL; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; EVALUATION; FEASIBILITY STUDY; GENETIC PROCEDURES; HUMAN; INSTRUMENTATION; ISOMERISM; MACROMOLECULE; METHODOLOGY; RAT; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

ANIMALS; BIOSENSING TECHNIQUES; FEASIBILITY STUDIES; HUMANS; ISOMERISM; MACROMOLECULAR SUBSTANCES; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SERUM ALBUMIN; SURFACE PLASMON RESONANCE;

EID: 0346119854     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0956-5663(02)00139-2     Document Type: Article

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