Synthesis and Pharmacological Evaluation of Fenamate Analogues: 1,3,4-Oxadiazol-2-ones and 1,3,4-Oxadiazole-2-thiones

Scientia Pharmaceutica

Volumn 71, Issue 4, 2003, Pages 331-356

  El Azzounyl, Aida A ^a   Maklad, Yousreya A ^a   Bartsch, Herbert ^b   Zaghary, Wafaa A ^c   Ibrahim, Waleed M ^c   Mohamed, Mosaad S ^c  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b UNIVERSITY OF VIENNA   (Austria)

^c Ein Helwan   (Egypt)

Author keywords

1,3,4 oxadiazol 2 ones and 2 thiones; Analgesics; Fenamate analogues; Nonsteroidal antiinflammatories

Indexed keywords

2 (4 PYRIDYL)AMINOPHENYLOXADIAZOL 2(3H) ONE; 5 [2 (7 CHLORO 3 ETHOXYCARBONYLQUINOLIN 4 YLAMINO)PHENYL] 3H [1,3,4]OXADIAZOL 2 ONE; 5 [2 (7 CHLORO 3 ETHOXYCARBONYLQUINOLIN 4 YLAMINO)PHENYL] 3H [1,3,4]OXADIAZOLE 2 THIONE; 5 [2 (7 CHLOROQUINOLIN 4 YLAMINO)PHENYL] 3H [1,3,4]OXADIAZOLE 2 THIONE; 5 [2 (7 TRIFLUOROMETHYLQUINOLIN 4 YLAMINO)PHENYL] 3H [1,3,4]OXADIAZOL 2 ONE; 5 [4,5 DIMETHOXY 2 (PYRIDIN 4 YLAMINO)PHENYL] 3H [1,3,4]OXADIAZOL 2 ONE; 5 [4,5 DIMETHOXY 2 (PYRIDIN 4 YLAMINO)PHENYL] 3H [1,3,4]OXADIAZOLE 2 THIONE; FENAMIC ACID DERIVATIVE; INDOMETACIN; MEFENAMIC ACID; OXADIAZOLE DERIVATIVE; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; MALE; NONHUMAN; PAW EDEMA; PROSTAGLANDIN BLOOD LEVEL; RAT; STATISTICAL SIGNIFICANCE; ULCEROGENESIS;

EID: 0346099438     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: 10.3797/scipharm.aut-03-28     Document Type: Article

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