Plasma Adrenomedullin and Obstructive Sleep Apnea

American Journal of Hypertension

Volumn 17, Issue 1, 2004, Pages 74-76

  Wolk, Robert ^a   Svatikova, Anna ^a   Otto, Maria E ^a   Hoffmann, Michal S ^a   Duenwald, Carolyn J ^a   Somers, Virend K ^a  

^a MAYO CLINIC   (United States)

Author keywords

Adrenomedullin; Continuous positive airway pressure; Sleep apnea

Indexed keywords

ADRENOMEDULLIN;

AIRWAY PRESSURE; ARTICLE; BLOOD ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; MALE; PATIENT MONITORING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SLEEP APNEA SYNDROME;

EID: 0346059326     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2003.09.004     Document Type: Article

References (15)

1. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S: The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-1235.
2. Wolk R, Kara T, Somers VK: Sleep-disordered breathing and cardiovascular disease. Circulation 2003;108:9-12.
3. Kato M, Roberts-Thomson P, Phillips BG, Haynes WG, Winnicki M, Accurso V, Somers VK: Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea. Circulation 2000;102:2607-2610.
4. Sugo S, Minamino N, Kangawa K, Miyamoto K, Kitamura K, Sakata J, Eto T, Matsuo H: Endothelial cells actively synthesize and secrete adrenomedullin. Biochem Biophys Res Commun 1994;201:1160-1166.
5. Sugo S, Minamino N, Shoji H, Kangawa K, Kitamura K, Eto T, Matsuo H: Production and secretion of adrenomedullin from vascular smooth muscle cells: augmented production by tumor necrosis factor-alpha. Biochem Biophys Res Commun 1994;203:719-726.
6. Kitamura K, Kangawa K, Eto T: Adrenomedullin and PAMP: discovery, structures, and cardiovascular functions. Microsc Res Tech 2002;57:3-13.
7. Ishimitsu T, Nishikimi T, Saito Y, Kitamura K, Eto T, Kangawa K, Matsuo H, Omae T, Matsuoka H: Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest 1994;94:2158-2161.
8. Kitamura K, Ichiki Y, Tanaka M, Kawamoto M, Emura J, Sakakibara S, Kangawa K, Matsuo H, Eto T: Immunoreactive adrenomedullin in human plasma. FEBS Lett 1994;341:288-290.
9. Kohno M, Hanehira T, Kano H, Horio T, Yokokawa K, Ikeda M, Minami M, Yasunari K, Yoshikawa J: Plasma adrenomedullin concentrations in essential hypertension. Hypertension 1996:27:102-107.
10. Sumimoto T, Nishikimi T, Mukai M, Matsuzaki K, Murakami E, Takishita S, Miyata A, Matsuo H, Kangawa K: Plasma adrenomedullin concentrations and cardiac and arterial hypertrophy in hypertension. Hypertension 1997;30:741-745.
11. Peppard PE, Young T, Palta M, Skatrud J: Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000;342:1378-1384.
12. Minamino N, Kikumoto K, Isumi Y: Regulation of adrenomedullin expression and release. Microsc Res Tech 2002;57:28-39.
13. Somers VK, Dyken ME, Clary MP, Abboud FM: Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995;96:1897-1904.
14. Phillips BG, Narkiewicz K, Pesek CA, Haynes WG, Dyken ME. Somers VK: Effects of obstructive sleep apnea on endothelin-1 and blood pressure. J Hypertens 1999;17:61-66.
15. Meeran K, O'Shea D, Upton PD, Small CJ, Ghatei MA, Byfield PH, Bloom SR: Circulating adrenomedullin does not regulate systemic blood pressure but increases plasma prolactin after intravenous infusion in humans: a pharmacokinetic study. J Clin Endocrinol Metab 1997;82:95-100.