Celecoxib simulates respiratory burst through pertussis toxin-sensitive G-protein, a possible signal for β2-integrin expression on human neutrophils

European Journal of Pharmacology

Volumn 484, Issue 1, 2004, Pages 29-39

  Chang Hui, Liao ^a   Yen Ju, Hsiech ^a   Yin Chou, Lin ^b  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Ca2+ intracellular; Celecoxib; Cyclooxygenase 2; Genistein; Neutrophil; Protein kinase C (PKC); Respiratory burst; Superoxide anion

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; BETA2 INTEGRIN; CALCIUM; CELECOXIB; DIPHENYLIODONIUM SALT; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GENISTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTTLERIN; STAUROSPORINE; SUPEROXIDE; SUPEROXIDE DISMUTASE; WORTMANNIN;

ADULT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME LOCALIZATION; FEMALE; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY BURST;

EID: 0346056790     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.10.054     Document Type: Article

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