Clinical phenotype of haemoglobin Q-H disease

Journal of Clinical Pathology

Volumn 57, Issue 1, 2004, Pages 81-82

  Leung, K F S ^a   Ma, E S K ^a   Chan, A Y Y ^a   Chan, L C ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A; HEMOGLOBIN H;

ADOLESCENT; ADULT; ARTICLE; CHINESE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENOTYPE; HEMOGLOBIN DETERMINATION; HEMOGLOBIN Q H DISEASE; HEMOGLOBINOPATHY; HUMAN; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; THAILAND;

ADOLESCENT; ADULT; AGED; FEMALE; HEMOGLOBIN A; HEMOGLOBIN H; HEMOGLOBINS, ABNORMAL; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; THALASSEMIA;

EID: 0345863811     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.57.1.81     Document Type: Article

References (6)

1. Lie-Injo LE, Dozy AM, Kan YW, et al. The α-globin gene adjacent to the gene for Hb Q - α 74 Asp → His is deleted, but not that adjacent to the gene for Hb G - α 30 Glu → Gln; three fourths of the α-globin gene are deleted in Hb Q-α-thalossemia. Blood 1979;54:1407-16.
2. Higgs DR, Hung DM, Drysdale HC, et al. The genetic basis of Hb Q-H disease. Br J Haematol 1980;46:387-400.
3. Huisman THJ, Carver MFH, et al. A syllabus of human hemoglobin variants, 2nd ed. Augusta, Georgia: The Sickle Cell Anemia Foundation, 1996.
4. Tan J, Toy JS, Wong YC, et al. Molecular analysis of Hb Q-H disease and Hb Q-E in a Singaporean family. Southeast Asian J Trop Med Public Health 1995;26:252-6.
5. Lie-Injo LE, Pillay RP, Thuraisingham V. Further cases of Hb Q-H disease (Hb Q-α thalossemia). Blood 1966;28:830-9.
6. Chen FE, Ooi C, Ha SY, et al. Genetic and clinical features of hemoglobin H disease in Chinese patients. N Engl J Med 2000;343:544-50.