Changes in plasma lipids and markers of oxidative stress in normal pregnancy and pregnancies complicated by diabetes

Clinical Science

Volumn 106, Issue 1, 2004, Pages 93-98

  Toescu, V ^a   Nuttall, S L ^a   Martin, U ^a   Nightingale, P ^a   Kendall, M J ^a   Brydon, P ^a   Dunne, F ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Diabetes; Lipids; Oxidative stress; Pregnancy

Indexed keywords

BIOLOGICAL MARKER; CHOLESTEROL; LIPID; LIPID HYDROPEROXIDE; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CALORIMETRY; CARDIOVASCULAR RISK; CHEMOLUMINESCENCE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH RISK PREGNANCY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PREECLAMPSIA; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; THIRD TRIMESTER PREGNANCY; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; ANALYSIS OF VARIANCE; ANTHROPOMETRY; ANTIOXIDANTS; BIOLOGICAL MARKERS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETES, GESTATIONAL; FEMALE; HUMANS; LIPIDS; OXIDATIVE STRESS; PREGNANCY; PREGNANCY IN DIABETICS;

EID: 0345863736     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20030175     Document Type: Article

References (32)

1. Edmunds, E. and Lip, G. Y. H. (2000) Cardiovascular risk in women: the cardiologists perspective. Q. J. Med. 93, 135-145
2. Hu, F. B., Stampfer, M. J., Manson, J. E. et al. (2000) Trends in the incidence of coronary artery disease and changes in diet and lifestyle in women. N. Engl. J. Med. 343, 530-537
3. Hu, F. B., Manson, J. E., Stampfer, M. J. et al. (2001) Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N. Engl. J. Med. 345, 790-797
4. Ness, R. B., Harris, T., Cobb, J. et al. (1993) Number of pregnancies and the subsequent risk of cardiovascular disease. N. Engl. J. Med. 328, 1528-1533
5. Lawlor, D. A., Emberson, J. R., Ebrahim, S. et al. (2003) Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings From the British Women's Heart and Health Study and the British Regional Heart Study. Circulation 107, 1260-1264
6. Diaz, M. N., Frei, B., Vita, J. A. and Keaney, J. F. (1997) Antioxidants and atherosclerotic heart disease. N. Engl. J. Med. 337, 408-415
7. Kendall, M. J. and Nuttall, S. L. (1999) Anti-oxidant therapy for the treatment of coronary artery disease. Expert Opin. Invest. Drugs 8, 1763-1784
8. Dejager, S., Brukert, E. and Chapman, M. J. (1993) Dense LDL subspecies with diminished oxidative resistance predominate in combined hyperlipidaemia. J. Lipid Res. 34, 295-308
9. Rajman, I., Eacho, P. I., Chowienczyk, P. J. and Ritter, J. M. (1999) LDL particle size: an important drug target? Br. J. Clin. Phanmcol. 48, 125-133
10. Steinberg, D., Parthasarathy, G., Carew, T. E., Khoo, J. C. and Witztum, J. L. (1989) Beyond cholesterol. Modifications of low density lipoprotein that increase its atherogenicity. N. Engl. J. Med. 320, 915-924
11. Sattar, N., Greer, I. A., Louden, J. et al. (1997) Lipoprotein subfraction changes in normal pregnancy: threshold effect of plasma triglyceride on appearance of small dense low density lipoprotein. J. Clin. Endocrinol. Metab. 82, 2483-2491
12. Brizzi, P., Tonolo, G., Esposito, F. et al. (1999) Lipoprotein metabolism during normal pregnancy. Am. J. Obstet. Gynaecol. 181, 430-434
13. Kaaja, R. (1998) Insulin resistance syndrome in pre-eclampsia. Sem. Reprod. Endocrinol. 16, 41-46
14. Ross, R. (1999) Atherosclerosis: an inflammatory disease. N. Engl. J. Med. 340, 115-126
15. Toescu, V., Nuttall, S. L., Martin, U., Kendall, M. J. and Dunne, F. (2002) Oxidative stress and normal pregnancy. Clin. Endocrinol. (Oxford) 57, 609-613
16. Gutteridge, J. M. C. (1995) Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin. Chem. 41, 1819-1828
17. Whitehead, T. P., Thorpe, G. H. G. and Maxwell, S. R. J. (1992) Enhanced chemiluminescent assay for antioxidant capacity in biological fluids. Anal. Chem. Acta 266, 265-277
18. Nourooz-Zadeh, J., Tajaddini-Sarmadi, J. and Wolff, S. P. (1994) Measurement of plasma hydroperoxide concentrations by the ferrous-oxidation- xylenol orange assay in conjunction with triphenylphosphine. Ann. Biochem. 220, 403-409
19. Rajman, I., Kendall, M. J., Cramb, R., Holder, R. L., Salih, M. and Gammage, M. D. (1996) Investigation of low-density lipoprotein subfractions as a coronary risk factor in normotriglyceridaemic men. Atherosclerosis 125, 231-242
20. Rajman, I., Lip, G. Y. H., Cramb, R. et al. (1996) Adverse change in low density lipoprotein subfractions profile with oestrogen-only hormone replacement therapy. Q. J. Med. 89, 771-778
21. Landray, M. J., Sagar, G., Muskin, J., Murray, S., Holder, R. L. and Lip, G. Y. H. (1998) Association of atherogenic low-density lipoprotein subfractions with carotid atherosclerosis. Q. J. Med. 91, 345-351
22. Martin, U., Davies, C., Hayavi, S., Hartland, A. and Dunne, F. (1999) Is normal pregnancy atherogenic? Clin. Sci. 96, 421-425
23. Landray, M. J., Nuttall, S. L., Maxwell, S. R. and Thorpe, G. H. (1998) Total antioxidant capacity by enhanced chemiluminescence: contribution of urate. Ann. Clin. Biochem. 35, 553-554
24. Nuttall, S. L., Dunne, F., Kendall, M. J. and Martin, U. (1999) Age-independent oxidative stress in elderly patients with non-insulin dependent diabetes mellitus. Q. J. Med. 92, 33-38
25. Hollingsworth, D. R. and Grundy, S. M. (1982) Pregnancy-associated hypertriglyceridaemia in normal and diabetic women. Differences in insulin-dependent, non-insulin dependent and gestational diabetes. Diabetes 31, 1092-1097
26. Montelongo, A., Lasuncion, M. A., Palardo, L. F. and Herrera, E. (1992) Longitudinal study of plasma lipoproteins and hormones during pregnancy in normal and diabetic women. Diabetes 41, 1651-1659
27. Koukkou, E., Watts, G. F. and Lowy, C. (1996) Serum lipid, lipoprotein and apolipoprotein changes in gestational diabetes mellitus: a cross-sectional and prospective study. J. Clin. Pathol. 49, 634-637
28. Maxwell, S. R. J., Thomason, H., Sandler, D. et al. (1997) Antioxidant status in patients with uncomplicated insulin-dependent and non-insulin- dependent diabetes mellitus. Eur. J. Clin. Invest. 27, 484-490
29. Chappell, L. C., Seed, P. T., Briley, A. L. et al. (1999) Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial. Lancet. 354, 810-816
30. Sagol, S., Ozkinay, E. and Ozsener, S. (1999) Impaired antioxidant activity in women with pre-eclampsia. Int. J. Gynecol. Obstet. 64, 121-127
31. Little, R. E. and Gladen, B. C. (1999) Levels of lipid peroxides in uncomplicated pregnancy: a review of the literature. Reprod. Toxicol. 13, 347-352
32. Nourooz-Zadeh, J., Tajaddini-Sarmandi, J., McCarthy, S., Betteridge, D. J. and Wolff, S. P. (1995) Elevated level of authentic plasma hydroperoxides in NIDDM. Diabetes 44, 1054-1058