The use of animal models in developing the discipline of cardiovascular tissue engineering: A review

Biomaterials

Volumn 25, Issue 9, 2004, Pages 1627-1637

  Rashid, S Tawqeer ^a   Salacinski, Henryk J ^a   Hamilton, George ^a   Seifalian, Alexander M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Animal model; Coronary; Graft; Heart; Tissue engineering; Vascular

Indexed keywords

CARDIOVASCULAR SYSTEM; DISEASES; IMPLANTS (SURGICAL); LIVING SYSTEMS STUDIES; PHYSIOLOGICAL MODELS;

TISSUE ENGINEERING;

HEART VALVE PROSTHESES;

POLITEF; POLYGLYCOLIC ACID;

ALLOGRAFT; AUTOGRAFT; BLOOD VESSEL GRAFT; BLOOD VESSEL PROSTHESIS; CARDIOVASCULAR DISEASE; COST; DACRON IMPLANT; DEVICE; ENDOTHELIUM CELL; ETHICS; EXPERIMENTAL ANIMAL; FOOD AND DRUG ADMINISTRATION; GRAFT SURVIVAL; HEART VALVE; HEART VALVE REPLACEMENT; HUMAN; IMPLANTATION; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; REVIEW; TISSUE ENGINEERING; XENOGRAFT; XENOTRANSPLANTATION;

ANIMALIA;

EID: 0345863373     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(03)00522-2     Document Type: Article

References (125)

1. Svedsen P, Hau J. Handbook of laboratory animal science, animal models, vol. II. Boca Raton, FL: CRC Press Inc.; 1994. p. 224.
2. World Health Organization. The World Health Report 1999. http://www.who.int .
3. Salacinski H.J., Goldner S., Giudiceandrea A., Hamilton G., Edwards A., Seifalian A.M. The mechanical behavior of vascular grafts. a review J Biomater Appl. 15:2001;241-278.
4. Hiatt W.R., Hoag S., Hamman R.F. Effect of diagnostic criteria on the prevalence of peripheral arterial disease. The San Luis Valley Diabetes Study. Circulation. 91:1995;1472-1479.
5. Fowkes F.G., Housley E., Riemersma R.A., Macintyre C.C., Cawood E.H., Prescott R.J.et al. Smoking, lipids, glucose intolerance, and blood pressure as risk factors for peripheral atherosclerosis compared with ischemic heart disease in the Edinburgh Artery Study. Am J Epidemiol. 135:1992;331-340.
6. Criqui M.H., Fronek A., Barrett-Connor E., Klauber M.R., Gabriel S., Goodman D. The prevalence of peripheral arterial disease in a defined population. Circulation. 71:1985;510-515.
7. Seifalian A.M., Tiwari A., Hamilton G., Salacinski H.J. Improving the clinical patency of prosthetic vascular and coronary bypass grafts. the role of seeding and tissue engineering Artif Organs. 26:2002;307-320.
8. Veith F.J., Moss C.M., Sprayregen S., Montefusco C. Preoperative saphenous venography in arterial reconstructive surgery of the lower extremity. Surgery. 85:1979;253-256.
9. Tai N.R., Salacinski H.J., Edwards A., Hamilton G., Seifalian A.M. Compliance properties of conduits used in vascular reconstruction. Br J Surg. 87:2000;1516-1524.
10. Tiwari A., Cheng K., Salacinski H.J., Hamilton G., Seifalian A.M. Improving the patency of vascular bypass grafts. the role of suture materials and surgical techniques on reducing anastomotic compliance mismatch Eur J Vasc Endovasc Surg. 25:2003;287-295.
11. Pourdeyhimi B., Wagner D. On the correlation between the failure of vascular grafts and their structural and material properties. a critical analysis J Biomed Mater Res. 20:1986;375-409.
12. Abbott W.M., Callow A., Moore W., Rutherford R., Veith F., Weinberg S. Evaluation and performance standards for arterial prostheses. J Vasc Surg. 17:1993;746-756.
13. Bennion R.S., Williams R.A., Stabile B.E., Fox M.A., Owens M.L., Wilson S.E. Patency of autogenous saphenous vein versus polytetrafluoroethylene grafts in femoropopliteal bypass for advanced ischemia of the extremity. Surg Gynecol Obstet. 160:1985;239-242.
14. L'Heureux N., Pâquet S., Labbé R., Germain L., Auger F.A. A completely biological tissue-engineered human blood vessel [see comments]. FASEB J. 12:1998;47-56.
15. Niklason L.E., Gao J., Abbott W.M., Hirschi K.K., Houser S., Marini R.et al. Functional arteries grown in vitro. Science. 284:1999;489-493.
16. Tiwari A., Kidane A., Punshon G., Hamilton G., Seifalian A.M. Extraction of cells for single stage seeding of vascular bypass grafts. Biotechnol Appl Biochem. 38:2003;35-41.
17. Nerem R.M., Seliktar D. Vascular tissue engineering. Annu Rev Biomed Eng. 3:2001;225-243.
18. Salacinski H.J., Tiwari A., Hamilton G., Seifalian A.M. Cellular engineering of vascular bypass grafts. role of chemical coatings for enhancing endothelial cell attachment Med Biol Eng Comput. 39:2001;609-618.
19. Tiwari A., Salacinski H.J., Hamilton G., Seifalian A.M. Tissue engineering of vascular bypass grafts. role of endothelial cell extraction Eur J Vasc Endovasc Surg. 21:2001;193-201.
20. Zilla P., Deutsch M., Meinhart J. Endothelial cell transplantation. Semin Vasc Surg. 12:1999;52-63.
21. Tiwari A., Salacinski H.J., Punshon G., Hamilton G., Seifalian A.M. Development of a hybrid cardiovascular graft using a tissue engineering approach. FASEB J. 16:2002;791-796.
22. Salacinski H.J., Punshon G., Krijgsman B., Hamilton G., Seifalian A.M. A hybrid compliant vascular graft seeded with microvascular endothelial cells extracted from human omentum. Artif Organs. 25:2001;974-982.
23. He H., Matsuda T. Arterial replacement with compliant hierarchic hybrid vascular graft. biomechanical adaptation and failure Tissue Eng. 8:2002;213-224.
24. Ishibashi K., Kawazoe K., Matsuda T. Development of a hybrid vascular graft hierarchically layered three cell types. Jpn J Artif Organs. 25:1996;733-737.
25. Kanda K., Matsuda T., Oka T. In vitro reconstruction of hybrid vascular tissue. Hierarchic and oriented cell layers. ASAIO J. 39:1993;M561-M565.
26. Kobashi T., Matsuda T. Fabrication of branched hybrid vascular prostheses. Tissue Eng. 5:1999;515-524.
27. Bloomfield P. Choice of heart valve prosthesis. Heart. 87:2002;583-589.
28. Stock U.A., Vacanti J.P., Mayer J.E. Jr., Wahlers T. Tissue engineering of heart valves - current aspects. Thorac Cardiovasc Surg. 50:2002;184-193.
29. Ades P.A. Cardiac rehabilitation and secondary prevention of coronary heart disease. N Engl J Med. 345:2001;892-902.
30. Hughes S. Cardiac stem cells. J Pathol. 197:2002;468-478.
31. Stamm C., Westphal B., Kleine H.D., Petzsch M., Kittner C., Klinge H.et al. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet. 361:2003;45-46.
32. Tse H.F., Kwong Y.L., Chan J.K., Lo G., Ho C.L., Lau C.P. Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet. 361:2003;47-49.
33. Langer R., Vacanti J.P. Tissue engineering. Science. 260:1993;920-926.
34. Murry C.E., Whitney M.L., Reinecke H. Muscle cell grafting for the treatment and prevention of heart failure. J Cardiovasc Fail. 8:2002;S532-S541.
35. Hagege A.A., Vilquin J.T., Bruneval P., Menasche P. Regeneration of the myocardium. a new role in the treatment of ischemic heart disease? Hypertension. 38:2001;1413-1415.
36. Hagege A.A., Carrion C., Menasche P., Vilquin J.T., Duboc D., Marolleau J.P.et al. Viability and differentiation of autologous skeletal myoblast grafts in ischaemic cardiomyopathy. Lancet. 361:2003;491-492.
37. Siminiak T., Kalawski R., Fiszer D., Jerzykowska O., Rzezniczak J., Kurpisz M. Skeletal myoblast transplantation during bypass grafting in the treatment of heart failure-phase I clinical trial feasibility study and early results. Heart Surg Forum. 6:2002;3.
38. Nerem R.M. Cellular engineering. Ann Biomed Eng. 19:1991;529-545.
39. Deutsch M., Meinhart J., Fischlein T., Preiss P., Zilla P. Clinical autologous in vitro endothelialization of infrainguinal ePTFE grafts in 100 patients. a 9-year experience Surgery. 126:1999;847-855.
40. Laube H.R., Duwe J., Rutsch W., Konertz W. Clinical experience with autologous endothelial cell-seeded polytetrafluoroethylene coronary artery bypass grafts. J Thorac Cardiovasc Surg. 120:2000;134-141.
41. Shin'oka T., Imai Y., Ikada Y. Transplantation of a tissue-engineered pulmonary artery. N Engl J Med. 344:2001;532-533.
42. Dohmen P.M., Lembcke A., Hotz H., Kivelitz D., Konertz W.F. Ross operation with a tissue-engineered heart valve. Ann Thorac Surg. 74:2002;1438-1442.
43. Berger K., Sauvage L.R., Rao A.M., Wood S.J. Healing of arterial prostheses in man. its incompleteness Ann Surg. 175:1972;118-127.
44. Sauvage L.R., Berger K.E., Wood S.J., Yates S.G., Smith J.C., Mansfield P.B. Interspecies healing of porous arterial prostheses. Observations, 1960-1974. Arch Surg. 109:1974;698-705.
45. Wolfensohn S., Lloyd M. Handbook of laboratory animal management and welfare. 2nd ed:1998;Blackwell Science, Oxford.
46. Clowes A.W., Kirkman T.R., Clowes M.M. Mechanisms of arterial graft failure II. Chronic endothelial and smooth muscle cell proliferation in healing polytetrafluoroethylene prostheses. J Vasc Surg. 3:1986;877-884.
47. Zilla P., Preiss P., Groscurth P., Rosemeier F., Deutsch M., Odell J.et al. In vitro-lined endothelium. initial integrity and ultrastructural events Surgery. 116:1994;524-534.
48. Hansen S.B., Nielsen S.L., Christensen T.D., Gravergaard A.E., Baandrup U., Bille S.et al. Latissimus dorsi cardiomyoplasty. a chronic experimental porcine model. Feasibility study of cardiomyoplasty in Danish Landrace pigs and Gottingen minipigs Lab Anim Sci. 48:1998;483-489.
49. Robotin-Johnson M.C., Swanson P.E., Johnson D.C., Schuessler R.B., Cox J.L. An experimental model of small intestinal submucosa as a growing vascular graft. J Thorac Cardiovasc Surg. 116:1998;805-811.
50. Panetta C.J., Miyauchi K., Berry D., Simari R.D., Holmes D.R., Schwartz R.S.et al. A tissue-engineered stent for cell-based vascular gene transfer. Hum Gene Ther. 13:2002;433-441.
51. Baguneid M.S., Goldner S., Fulford P.E., Hamilton G., Walker M.G., Seifalian A.M. A comparison of para-anastomotic compliance profiles after vascular anastomosis. nonpenetrating clips versus standard sutures J Vasc Surg. 33:2001;812-820.
52. Shum-Tim D., Stock U., Hrkach J., Shinoka T., Lien J., Moses M.A.et al. Tissue engineering of autologous aorta using a new biodegradable polymer. Ann Thorac Surg. 68:1999;2298-2304.
53. Elkins R.C., Goldstein S., Hewitt C.W., Walsh S.P., Dawson P.E., Ollerenshaw J.D.et al. Recellularization of heart valve grafts by a process of adaptive remodeling. Semin Thorac Cardiovasc Surg. 13:2001;87-92.
54. Dohmen P.M., Ozaki S., Yperman J., Flameng W., Konertz W. Lack of calcification of tissue engineered heart valves in juvenile sheep. Semin Thorac Cardiovasc Surg. 13:2001;93-98.
55. Elkins R.C. Tissue-engineered valves. Ann Thorac Surg. 74:2002;1434.
56. Stamm C., Steinhoff G. Cardiac tissue engineering. Herz. 27:2002;445-452.
57. Watanabe M., Shin'oka T., Tohyama S., Hibino N., Konuma T., Matsumura G.et al. Tissue-engineered vascular autograft. inferior vena cava replacement in a dog model Tissue Eng. 7:2001;429-439.
58. Niu S., Kurumatani H., Satoh S., Kanda K., Oka T., Watanabe K. Small diameter vascular prostheses with incorporated bioabsorbable matrices. A preliminary study. ASAIO J. 39:1993;M750-M753.
59. Noishiki Y., Yamane Y., Satoh S., Niu S., Okoshi T., Tomizawa Y.et al. Healing process of vascular prostheses seeded with venous tissue fragments. ASAIO Trans. 37:1991;M478-M480.
60. Noishiki Y., Yamane Y., Okoshi T., Tomizawa Y., Satoh S. Choice, isolation, and preparation of cells for bioartificial vascular grafts. Artif Organs. 22:1998;50-62.
61. Noishiki Y., Ichikawa Y., Kosuge T., Yamazaki I., Yamamoto K., Manabe T.et al. Introduction of tissue engineering concepts into the field of endovascular grafts. an attempt to solve endoleakage problems of endovascular grafts implanted in aortic aneurysms Artif Organs. 25:2001;228-235.
62. Marois Y., Paris E., Zhang Z., Doillon C.J., King M.W., Guidoin R.G. Vascugraft microporous polyesterurethane arterial prosthesis as a thoraco-abdominal bypass in dogs. Biomaterials. 17:1996;1289-1300.
63. Seifalian A.M., Salacinski H.J., Tiwari A., Edwards A., Bowald S., Hamilton G. In vivo biostability of a poly(carbonate-urea)urethane graft. Biomaterials. 24:2003;2549-2557.
64. Shindo S., Takagi A., Whittemore A.D. Improved patency of collagen-impregnated grafts after in vitro autogenous endothelial cell seeding. J Vasc Surg. 6:1987;325-332.
65. Miwa H., Matsuda T. An integrated approach to the design and engineering of hybrid arterial prostheses. J Vasc Surg. 19:1994;658-667.
66. Conklin B.S., Richter E.R., Kreutziger K.L., Zhong D.S., Chen C. Development and evaluation of a novel decellularized vascular xenograft. Med Eng Phys. 24:2002;173-183.
67. Clarke D.R., Lust R.M., Sun Y.S., Black K.S., Ollerenshaw J.D. Transformation of nonvascular acellular tissue matrices into durable vascular conduits. Ann Thorac Surg. 71:2001;S433-S436.
68. Lantz G.C., Badylak S.F., Hiles M.C., Coffey A.C., Geddes L.A., Kokini K.et al. Small intestinal submucosa as a vascular graft. A review J Invest Surg. 6:1993;297-310.
69. Lantz G.C., Badylak S.F., Coffey A.C., Geddes L.A., Blevins W.E. Small intestinal submucosa as a small-diameter arterial graft in the dog. J Invest Surg. 3:1990;217-227.
70. Hirai J., Matsuda T. Venous reconstruction using hybrid vascular tissue composed of vascular cells and collagen. tissue regeneration process Cell Transplant. 5:1996;93-105.
71. Matsuda T., Miwa H. A hybrid vascular model biomimicking the hierarchic structure of arterial wall. neointimal stability and neoarterial regeneration process under arterial circulation J Thorac Cardiovasc Surg. 110:1995;988-997.
72. Ishibashi K., Matsuda T. Reconstruction of a hybrid vascular graft hierarchically layered with three cell types. ASAIO J. 40:1994;M284-M290.
73. Miwa H., Matsuda T., Iida F. Development of a hierarchically structured hybrid vascular graft biomimicking natural arteries. ASAIO J. 39:1993;M273-M277.
74. Miwa H., Matsuda T., Kanda K. Development of a hierarchically structured hybrid vascular graft. Jpn J Artif Organs. 22:1993;468-472.
75. Kanda K., Miwa H., Matsuda T. Phenotypic reversion of smooth muscle cells in hybrid vascular prostheses. Cell Transplant. 4:1995;587-595.
76. Kanda K., Matsuda T., Miwa H., Oka T. Phenotypic modulation of smooth muscle cells in intima-media incorporated hybrid vascular prostheses. ASAIO J. 39:1993;M278-M282.
77. Sparks S.R., Tripathy U., Broudy A., Bergan J.J., Kumins N.H., Owens E.L. Small-caliber mesothelial cell-layered polytetraflouroethylene vascular grafts in New Zealand white rabbits. Ann Vasc Surg. 16:2002;73-76.
78. Campbell J.H., Efendy J.L., Campbell G.R. Novel vascular graft grown within recipient's own peritoneal cavity. Circ Res. 85:1999;1173-1178.
79. Tsukagoshi T., Yenidunya M.O., Sasaki E., Suse T., Hosaka Y. Experimental vascular graft using small-caliber fascia-wrapped fibrocollagenous tube. short-term evaluation J Reconstr Microsurg. 15:1999;127-131.
80. Wong A.H., Waugh J.M., Amabile P.G., Yuksel E., Dake M.D. In vivo vascular engineering. directed migration of smooth muscle cells to limit neointima Tissue Eng. 8:2002;189-199.
81. Cebotari S., Walles T., Sorrentino S., Haverich A., Mertsching H. Guided tissue regeneration of vascular grafts in the peritoneal cavity. Circ Res. 90:2002;e71.
82. Kuo M.D., Waugh J.M., Yuksel E., Weinfeld A.B., Yuksel M., Dake M.D. ARRS President's Award. The potential of in vivo vascular tissue engineering for the treatment of vascular thrombosis. a preliminary report. American Roentgen Ray Society AJR Am J Roentgenol. 171:1998;553-558.
83. Eschenhagen T., Didie M., Heubach J., Ravens U., Zimmermann W.H. Cardiac tissue engineering. Transplant Immunol. 9:2002;315-321.
84. Shimizu T., Yamato M., Isoi Y., Akutsu T., Setomaru T., Abe K.et al. Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ Res. 90:2002;e40.
85. Noah E.M., Winkel R., Schramm U., Kuhnel W. Impact of innervation and exercise on muscle regeneration in neovascularized muscle grafts in rats. Ann Anat. 184:2002;189-197.
86. Liu S.Q. Prevention of focal intimal hyperplasia in rat vein grafts by using a tissue engineering approach. Atherosclerosis. 140:1998;365-377.
87. Liu S.Q., Moore M.M., Yap C. Prevention of mechanical stretch-induced endothelial and smooth muscle cell injury in experimental vein grafts. J Biomech Eng. 122:2000;31-38.
88. Kobayashi H., Kabuto M., Ide H., Hosotani K., Kubota T. An artificial blood vessel with an endothelial-cell monolayer. J Neurosurg. 77:1992;397-402.
89. Yue X., van der L.B., Schakenraad J.M., van Oene G.H., Kuit J.H., Feijen J.et al. Smooth muscle cell seeding in biodegradable grafts in rats. a new method to enhance the process of arterial wall regeneration Surgery. 103:1988;206-212.
90. Nathan A., Nugent M.A., Edelman E.R. Tissue engineered perivascular endothelial cell implants regulate vascular injury. Proc Natl Acad Sci USA. 92:1995;8130-8134.
91. Ding Z., Fournier R.L. Oxygen and inulin transport measurements in a planar tissue-engineered bioartificial organ. Tissue Eng. 8:2002;25-36.
92. Baldwin H.S. Advances in understanding the molecular regulation of cardiac development. Curr Opin Pediatr. 11:1999;413-418.
93. Abdessalem S.B., Chakfe N., Le Magnen J.F., Beaufigeau M., Adolphe D., Geny B.et al. Influence of crimping textile polyester vascular prostheses on the fluid flow kinetics. Groupe Europeen de Recherche sur les Protheses appliquees a la Chirurgie Vasculaire. Eur J Vasc Endovasc Surg. 18:1999;375-380.
94. Okamura S., Suzuki A., Johkura K., Ogiwara N., Harigaya M., Yokouchi T. et al. Formation of the biopulsatile vascular pump by cardiomyocyte transplants circumvallating the abdominal aorta. Tissue Eng. 8:2002;201-211.
95. Rupp P.A., Little C.D. Integrins in vascular development. Circ Res. 89:2001;566-572.
96. Nor J.E., Peters M.C., Christensen J.B., Sutorik M.M., Linn S., Khan M.K.et al. Engineering and characterization of functional human microvessels in immunodeficient mice. Lab Invest. 81:2001;453-463.
97. Hu Y., Zou Y., Dietrich H., Wick G., Xu Q. Inhibition of neointima hyperplasia of mouse vein grafts by locally applied suramin. Circulation. 100:1999;861-868.
98. Adams D.H., Chen R.H., Kadner A. Cardiac xenotransplantation. clinical experience and future direction Ann Thorac Surg. 70:2000;320-326.
99. Appel J.Z . III, Buhler L., Cooper D.K. The pig as a source of cardiac xenografts. J Cardvasc Surg. 16:2001;345-356.
100. Cooper D.K., Keogh A.M., Brink J., Corris P.A., Klepetko W., Pierson R.N.et al. Report of the Xenotransplantation Advisory Committee of the International Society for Heart and Lung Transplantation. the present status of xenotransplantation and its potential role in the treatment of end-stage cardiac and pulmonary diseases J Heart Lung Transplant. 19:2000;1125-1165.
101. Hodde J. Naturally occurring scaffolds for soft tissue repair and regeneration. Tissue Eng. 8:2002;295-308.
102. Hodde J.P., Record R.D., Tullius R.S., Badylak S.F. Retention of endothelial cell adherence to porcine-derived extracellular matrix after disinfection and sterilization. Tissue Eng. 8:2002;225-234.
103. Schmidt C.E., Baier J.M. Acellular vascular tissues. natural biomaterials for tissue repair and tissue engineering Biomaterials. 21:2000;2215-2231.
104. O'brien M.F., Clarebrough J.K. Preliminary communication heterograft aortic valve transplantation for human valve disease. Med J Aust. 2:1966;228-230.
105. Goldstein S., Clarke D.R., Walsh S.P., Black K.S., O'brien M.F. Transpecies heart valve transplant. advanced studies of a bioengineered xeno-autograft Ann Thorac Surg. 70:2000;1962-1969.
106. Steinhoff G., Stock U., Karim N., Mertsching H., Timke A., Meliss R.R.et al. Tissue engineering of pulmonary heart valves on allogenic acellular matrix conduits. in vivo restoration of valve tissue Circulation. 102:2000;III50-III55.
107. Bader A., Steinhoff G., Strobl K., Schilling T., Brandes G., Mertsching H.et al. Engineering of human vascular aortic tissue based on a xenogeneic starter matrix. Transplantation. 70:2000;7-14.
108. Korossis S.A., Booth C., Wilcox H.E., Watterson K.G., Kearney J.N., Fisher J.et al. Tissue engineering of cardiac valve prostheses II. biomechanical characterization of decellularized porcine aortic heart valves J Heart Valve Dis. 11:2002;463-471.
109. Booth C., Korossis S.A., Wilcox H.E., Watterson K.G., Kearney J.N., Fisher J.et al. Tissue engineering of cardiac valve prostheses I. development and histological characterization of an acellular porcine scaffold J Heart Valve Dis. 11:2002;457-462.
110. Laube H.R., Matthaus M. A new semi-automatic endothelial cell seeding technique for biological prosthetic heart valves. Int J Artif Organs. 24:2001;243-246.
111. Cai D., Marty-Roix R., Hsu H.P., Spector M. Lapine and canine bone marrow stromal cells contain smooth muscle actin and contract a collagen-glycosaminoglycan matrix. Tissue Eng. 7:2001;829-841.
112. Goissis G., Suzigan S., Parreira D.R., Maniglia J.V., Braile D.M., Raymundo S. Preparation and characterization of collagen-elastin matrices from blood vessels intended as small diameter vascular grafts. Artif Organs. 24:2000;217-223.
113. van Luyn M., Tio R., van S.X., Plantinga J., de Leij L., DeJongste M.et al. Cardiac tissue engineering. characteristics of in unison contracting two- and three-dimensional neonatal rat ventricle cell (co)-cultures Biomaterials. 23:2002;4793-4801.
114. Kofidis T., Akhyari P., Boublik J., Theodorou P., Martin U., Ruhparwar A.et al. In vitro engineering of heart muscle. artificial myocardial tissue J Thorac Cardiovasc Surg. 124:2002;63-69.
115. Carrier R.L., Rupnick M., Langer R., Schoen F.J., Freed L.E., Vunjak-Novakovic G. Perfusion improves tissue architecture of engineered cardiac muscle. Tissue Eng. 8:2002;175-188.
116. Carrier R.L., Rupnick M., Langer R., Schoen F.J., Freed L.E., Vunjak-Novakovic G. Effects of oxygen on engineered cardiac muscle. Biotechnol Bioeng. 78:2002;617-625.
117. Zimmermann W.H., Schneiderbanger K., Schubert P., Didie M., Munzel F., Heubach J.F.et al. Tissue engineering of a differentiated cardiac muscle construct. Circ Res. 90:2002;223-230.
118. Cassell O.C., Morrison W.A., Messina A., Penington A.J., Thompson E.W., Stevens G.W.et al. The influence of extracellular matrix on the generation of vascularized, engineered, transplantable tissue. Ann NY Acad Sci. 944:2001;429-442.
119. Saxena A.K., Willital G.H., Vacanti J.P. Vascularized three-dimensional skeletal muscle tissue-engineering. Biomed Mater Eng. 11:2001;275-281.
120. 2+ tolerant cardiomyocytes from the adult rat. improvements and applications Xenobiotica. 30:2000;1063-1077.
121. Papadaki M., Bursac N., Langer R., Merok J., Vunjak-Novakovic G., Freed L.E. Tissue engineering of functional cardiac muscle. molecular, structural, and electrophysiological studies Am J Physiol Heart Circ Physiol. 280:2001;H168-H178.
122. Leor J., Aboulafia-Etzion S., Dar A., Shapiro L., Barbash I.M., Battler A.et al. Bioengineered cardiac grafts. a new approach to repair the infarcted myocardium? Circulation. 102:2000;III56-III61.
123. Bursac N., Papadaki M., Cohen R.J., Schoen F.J., Eisenberg S.R., Carrier R.et al. Cardiac muscle tissue engineering. toward an in vitro model for electrophysiological studies Am J Physiol. 277:1999;H433-H444.
124. Carrier R.L., Papadaki M., Rupnick M., Schoen F.J., Bursac N., Langer R.et al. Cardiac tissue engineering. cell seeding, cultivation parameters, and tissue construct characterization Biotechnol Bioeng. 64:1999;580-589.
125. Akins R.E., Boyce R.A., Madonna M.L., Schroedl N.A., Gonda S.R., McLaughlin T.A.et al. Cardiac organogenesis in vitro. reestablishment of three-dimensional tissue architecture by dissociated neonatal rat ventricular cells Tissue Eng. 5:1999;103-118.