Effects of lithium and valproate on agonist-induced platelet intracellular calcium mobilization: Relevance to myosin light chain kinase

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 28, Issue 1, 2004, Pages 67-72

  Suzuki, Katsuji ^a   Kusumi, Ichiro ^a   Akimoto, Tatsuyuki ^a   Sasaki, Yuki ^a   Koyama, Tsukasa ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bipolar disorder; Lithium; Myosin light chain kinase; Platelet; Valproate

Indexed keywords

1 (5 CHLORO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; CALCIUM; LITHIUM CHLORIDE; MYOSIN LIGHT CHAIN KINASE INHIBITOR; SEROTONIN CREATININE SULFATE; THROMBIN; VALPROIC ACID;

AGONIST; ANTICONVULSANT ACTIVITY; ARTICLE; BIPOLAR DISORDER; CALCIUM BLOOD LEVEL; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN EXPERIMENT; INCUBATION TIME; LITHIUM BLOOD LEVEL; MALE; NORMAL HUMAN; THROMBOCYTE AGGREGATION;

EID: 0345734355     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2003.09.021     Document Type: Article

References (27)

1. Adelstein R.S., Conti M.A. Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity. Nature. 256:1975;597-598.
2. Bowden C.L., Janicak P.G., Orsulak P., Swann A.C., Davis J.M., Calabrese J.R., Goodnick P., Small J.G., Rush A.J., Kimmel S.E., Risch S.C., Morris D.D. Relation of serum valproate concentration to response in mania. Am. J. Psychiatry. 153:1996;765-770.
3. Bowden C.L., Calabrese J.R., McElroy S.L., Gyulai L., Wassef A., Petty F., Pope H.G. Jr., Chou J.C.Y., Keck P.E. Jr., Rhodes L.J., Swann A.C., Hirschfeld R.M.A., Wozniak P.J. A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Arch. Gen. Psychiatry. 57:2000;481-489.
4. Dubovsky S.L., Christiano J., Daniell L.C., Franks R.D., Murphy J., Adler L., Baker N., Harris A. Increased platelet intracellular calcium concentration in patients with bipolar affective disorders. Arch. Gen. Psychiatry. 46:1989;632-638.
5. Dubovsky S.L., Lee C., Christiano J., Murphy J. Elevated platelet intracellular calcium concentration in bipolar depression. Biol. Psychiatry. 29:1991;441-450.
6. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:1985;3440-3450.
7. + on contractile elements of intestinal smooth muscle. Jpn. J. Pharmacol. 68:1995;111-118.
8. Ikebe M., Koretz J., Hartshorne D.J. Effects of phosphorylation of light chain residues threonine 18 and serine 19 on the properties and conformation of smooth muscle myosin. J. Biol. Chem. 263:1988;6432-6437.
9. Jian X., Hidaka H., Schmidt J.T. Kinase requirement for retinal growth cone motility. J. Neurobiol. 25:1994;1310-1328.
10. Johannessen C.U. Mechanism of action of valproate: a commentatory. Neurochem. Int. 37:2000;103-110.
11. 2A receptor-mediated intracellular calcium increase in human platelets. Pharm. Sci. 1:1995;141-143.
12. Kagaya A., Okada A., Tawara Y., Inagaki M., Jitsuiki H., Kozuru T., Miyoshi I., Katagiri H., Uchitomi Y., Horiguchi J., Nakata Y., Yamawaki S. Lithium chloride inhibits thrombin-induced intracellular calcium mobilization in C6 rat glioma cells. Prog. Neuropsychopharmacol. Biol. Psychiatry. 24:2000;85-95.
13. Khaitan L., Calabrese J.R., Stockmeier C.A. Effects of chronic treatment with valproate on serotonin-1A receptor binding and function. Psychopharmacology. 113:1994;539-542.
14. 2+ response in human platelets. Life Sci. 48:1991;2405-2412.
15. Kusumi I., Koyama T., Yamashita I. Serotonin-stimulated Ca response is increased in the blood platelets of depressed patients. Biol. Psychiatry. 30:1991;310-312.
16. Kusumi I., Koyama T., Yamashita I. Thrombin-induced platelet calcium mobilization is enhanced in bipolar disorder. Biol. Psychiatry. 32:1992;731-734.
17. Kusumi I., Koyama T., Yamashita I. Serotonin-induced platelet intracellular calcium mobilization in depressed patients. Psychopharmacology. 113:1994;322-327.
18. Kusumi I., Suzuki K., Sasaki Y., Takahashi Y., Kameda K., Koyama T. Treatment response in depressed patients with enhanced calcium mobilization stimulated by serotonin. Neuropsychopharmacology. 23:2000;690-696.
19. Lenox R.H., Hahn C.G. Overview of the mechanism of action of lithium in the brain: fifty-year update. J. Clin. Psychiatry. 61(Suppl. 9):2000;5-15.
20. Manji H.K., Bebchuk J.M., Moore G.J., Glitz D., Hasanat K.A., Chen G. Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications. J. Clin. Psychiatry. 60(Suppl. 2):1999;27-39.
21. McElroy S.L., Keck P.E. Experience with valproate in affective disorders. Modigh K., Robak O.H., Vestergaad P. Anticonvulsants in Psychiatry. 1994;57-72 Wrightson Biomedical Publishing, UK.
22. 2+-calmodulin-dependent phosphorylation and platelet secretion. Nature. 287:1980;863-865.
23. 2+ mobilization in rabbit platelets. Eur. J. Pharmacol. 298:1996;175-183.
24. Okamoto Y., Kagaya A., Shinno H., Motohashi N., Yamawaki S. Serotonin-induced platelet calcium mobilization is enhanced in mania. Life Sci. 56:1994;327-332.
25. Potier M.C., Chelot E., Pekarsky Y., Gardiner K., Rossier J., Turnell W.G. The human myosin light chain kinase (MLCK) from hippocampus: cloning, sequencing, expression, and localization to 3qcen-q21. Genomics. 29:1995;562-570.
26. Saitoh M., Naka M., Hidaka H. The modulatory role of myosin light chain phosphorylation in human platelet activation. Biochem. Biophys. Res. Commun. 140:1986;280-287.
27. Suzuki K., Kusumi I., Sasaki Y., Koyama T. Serotonin-induced platelet intracellular calcium mobilization in various psychiatric disorders: is it specific to bipolar disorder? J. Affect. Disord. 64:2001;291-296.