Purification from Bothrops lanceolatus (Fer de Lance) venom of a fibrino(geno)lytic enzyme with esterolytic activity

Toxicon

Volumn 36, Issue 5, 1998, Pages 745-758

  Lôbo De Araújo, Albetiza ^a   Donato, José L ^a   Bon, Cassian ^b  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

SNAKE VENOM;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; FIBRINOGENOLYSIS; GEL FILTRATION CHROMATOGRAPHY; IMMUNODIFFUSION; IMMUNOELECTROPHORESIS; ION EXCHANGE CHROMATOGRAPHY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; TOXIN ANALYSIS;

ANIMALS; BOTHROPS; CROTALID VENOMS; ESTERASES; FIBRINOLYTIC AGENTS; HYDROLYSIS; MOLECULAR WEIGHT; RABBITS; THROMBIN; TOSYLARGININE METHYL ESTER;

BOTHROPS; BOTHROPS ATROX; EQUIDAE; LONCHOCARPUS GLAUCIFOLIUS; ORYCTOLAGUS CUNICULUS; SERPENTES;

EID: 0345726054     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(97)00118-9     Document Type: Article

References (41)

1. Bjarnason, J. B. and Tu, A. T. (1978) Hemorrhagic toxins from western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e. Biochemistry 17, 3395-3404.
2. Blum, H., Beier, H. and Gross, H. J. (1987) Improved silver staining of plant proteins, RNA and DNA in polyacrylamide gels. Electrophoresis 8, 93-99.
3. Civello, D. J., Duong, H. L. and Geren, C. R. (1983) Isolation and characterization of the hemorrhagic proteinase from timber rattlesnake venom. Biochemistry 22, 749-755.
4. Grabar, P. and Burtin, P. (1964) Immuno-electrophoretic analysis. Elsevier, Amsterdam.
5. Hames, B. D. and Rickwood, D. (1982) An introduction to polyacrylamide gel electrophoresis. In Gel electrophroresis of proteins: a practical approach, eds. B. D. Hames, and D. Rickwood, pp. 2-91. IRL Press Limited, Oxford.
6. Hartree, E. F. (1972) Determination of protein: a modification of the Lowry method that gives a linear photometric response. Anal. Biochem. 48, 422-427.
7. Holleman, W. H. and Weiss, L. J. (1976) The thrombin-like enzyme from Bothrops atrox venom. J. Biol. Chem. 251, 1663-1669.
8. Hummel, B. C. W. (1959) A modified spectrophotometric determination of chymotrypsin, trypsin and thrombin. Can. J. Biochem. Physiol. 37, 1393-1397.
9. Iwanaga, S. and Suzuki, T. (1979) Enzymes in snake venom. In Snake Venoms. Handbook of Experimental Pharmacology, ed. C. Y. Lee, Vol. 52, pp. 61-158. Springer, Berlin.
10. Kornalik, F. (1985) The influence of snake venom enzymes on blood coagulation. Pharmacol. Ther. 29, 353-405.
11. Kunitz, M. (1946) Crystalline soybean trypsin inhibitor II. General properties. J. Gen. Physiol. 30, 291-310.
12. 2, blood-clotting, caseinolytic, esterolytic and hemorrhagic activities of some Bothrops snake venoms. Toxicon 28, 601.
13. 2 activity by a colorimetric assay using a pH indicator. Toxicon 25, 1181-1188.
14. 2 from Bothrops lanceolatus venom: purification and molecular, enzymatic and pharmacological properties. Toxicon 32, 1069-1081.
15. Magalhães, A., De Oliveira, G. J. and Diniz, C. R. (1981) Purification and partial characterization of a thrombin-like enzyme from the venom of the bushmaster snake, Lachesis muta noctivaga. Toxicon 19, 279-294.
16. Mandelbaum, F. R., Assakura, M. T. and Reichl, A. P. (1984) Characterization of two hemorrhagic factors isolated from the venom of Bothrops neuwiedi (jararaca pintada). Toxicon 22, 193-206.
17. Markland, F. S. (1983) Rattlesnake venom enzymes that interact with components of the hemostatic system. J. Toxicol. Toxin Rev. 2, 119-160.
18. Markland, F. S. and Damus, P. S. (1971) Purification and properties of a thrombin-like enzyme from the venom of Crotalus adamanteus (eastern diamondback rattlesnake). J. Biol. Chem. 246, 6460-6473.
19. Markland, F. S., Kettner, C., Schiffman, S., Shaw, E., Bajwa, S. S., Reddy, K. N. N., Kirakossian, H., Patkos, G. B., Theodor, I. and Pirkle, H. (1982) Kallikrein-like activity of crotalase, a snake venom enzyme that clots fibrinogen. Proc. Natl. Acad. Sci. U. S. A. 79, 1688-1692.
20. Minton, S. A. and Weinstein, S. A. (1984) Protease activity and lethal toxicity of venoms from some little known rattlesnakes. Toxicon 22, 828-830.
21. Mori, N., Nikai, T. and Sugihara, H. (1984) Purification of a proteinase (Ac5-proteinase) and characterization of hemorrhagic toxins from the venom of the hundred-pace snake (Agkistrodon acutus). Toxicon 22, 451-461.
22. Nahas, L., Kamiguti, A. S. and Barros, M. A. R. (1979) Thrombin-like and factor X-activator components of Bothrops venom. Thromb. Haemost. 41, 314-328.
23. Nikai, T., Sugihara, H. and Tanaka, T. (1977) Enzymochemical studies of snake venoms. II. Purification of lethal protein Ac1-proteinase in the venom of Agkistrodon acutus. J. Pharm. Soc. Jpn. 97, 507-514.
24. Nolan, C., Hall, L. and Barlow, G. H. (1976) Ancrod, the coagulation enzyme from Malayan pit viper (Agkistrodon rhodostoma) venom. Meth. Enzymol. 45, 205-214.
25. Ouyang, C. and Teng, C. M. (1976) The effects of the purified thrombin-like and anticoagulant principles of Agkistrodon acutus venom on blood coagulation in vivo. Toxicon 14, 45-49.
26. Ovadia, M. (1978) Isolation and characterization of three hemorrhagic factors from the venom of Vipera palaestinae. Toxicon 16, 479-487.
27. Sato, T., Iwanaga, S., Mizushima, Y. and Suzuki, T. (1965) Separation of arginine ester hydrolase of Agkistrodon halys blomhoffi venom into three enzymatic entities: bradykinin-releasing, clotting and permeability increasing. J. Biochem. 57, 380-391.
28. Schagger, H. and Jagow, G. V. (1987) Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins from 1 to 100 kDa. Anal. Biochem. 166, 368-379.
29. Selistre, H. S. and Giglio, J. R. (1987) Isolation and characterization of a thrombin-like enzyme from the venom of the snake Bothrops insularis (jararaca ilhoa). Toxicon 25, 1135-1144.
30. Siigur, E., Mahar, A. and Siigur, J. (1991) β-Fibrinogenase from the venom of Vipera lebetina. Toxicon 29, 107-118.
31. Stocker, K. and Barlow, G. H. (1976) The coagulant enzyme from Bothrops atrox venom (batroxobin). Meth. Enzymol. 45, 214-223.
32. Stocker, K., Christ, W. and Leloup, P. (1974) Characterization of the venoms of various Bothrops species by immunoelectrophoresis and reaction with fibrinogen agarose. Toxicon 12, 415-417.
33. Sugihara, H., Nikai, T., Nimura, A. and Tanaka, T. (1981) Enzymochemical studies on snake venoms. IX. Purification and properties of arginine ester hydrolases (HE-2) in the venom of Trimeresurus mucrosquamatus. J. Pharm. Soc. Jpn. 101, 153-162.
34. Sugihara, H., Nikai, T., Oda, H. and Tanaka, T. (1978) Enzymochemical studies on snake venoms. III. Purification and properties of arginine esterase which possesses clotting activity in the venom of Agkistrodon acutus. J. Pharm. Soc. Jpn. 98, 832-840.
35. Sugimori, M. H., Rodrigues Neto, J. and Oliveira, A. R. (1986) Novo meio de reação para testes serológicos de dupla difusão em ágar com antígenos de fitobactérias. Summa Phitopathologica 12, 33.
36. Teng, C. M., Wang, J. P., Huang, T. F. and Liau, M. Y. (1989) Effects of venom proteases on peptide chromogenic substrates and bovine prothrombin. Toxicon 27, 161-167.
37. Thomas, L., and Tyburn, B. (1996) Bothrops lanceolatus bites in Martinique: Clinical aspects and treatment. In Envenomings and Their Treatments, eds. C. Bon and M. Goyffon, pp. 255-265. Editions Fondation Marcel Mérieux, Lyons.
38. Thomas, L., Tyburn, B., Bucher, B., Pecout, F., Ketterle, J., Rieux, D., Smadja, D., Garnier, D. and Plumelle, Y. (1995) Prevention of thromboses in human patients with Bothrops lanceolatus envenoming in Martinique: failure of anticoagulants and efficacy of a monospecific antivenom. Am. J. Trop. Med. Hyg. 52, 419-426.
39. Thomas, L., Tyburn, B., Ketterle, J., Rieux, D., Guarnier, D. and Smadja, D. (1994) Troubles de la coagulation et thromboses induites par la morsure de serpent (Bothrops lanceolatus) chez I'homme em Martinique. Réanim. Urgence 3, 25-30.
40. Tu, A. T. (1988) Hemorrhagic factors. Hemorrhagic proteases from snake venoms. In Hemostasis and Animal Venoms, eds. H. Pirkle and F.S. Markland, pp. 425-455. Marcel Dekker, New York.
41. Willis, T. W. and Tu, A. T. (1988) Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom. Biochemistry 27, 4769-4777.