Performance evaluation of fiber optic probes for tissue lifetime fluorescence spectroscopy

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 4958, Issue , 2003, Pages 43-50

  Papaioannou, Thanassis ^a   Preyer, Norris ^b   Fang, Qiyin ^a   Kurt, Hamza ^a,b   Carnohan, Michael ^b   Ross, Russel ^b   Brightwell, Adam ^b   Cottone, Greg ^b   Jones, Linda ^b   Marcu, Laura ^a,c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b School of Business   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Diffuse reflectance; Fiberoptic probes; Fluorescence spectroscopy; Optical diagnostics; Optical properties

Indexed keywords

COMPUTER SIMULATION; FLUORESCENCE; LIGHT REFLECTION; MONTE CARLO METHODS; OPTICAL MICROSCOPY; OPTICAL PROPERTIES; PHOTONS; SIGNAL TO NOISE RATIO; TISSUE;

AGAR BASED TISSUE PHANTOM; BIFURCATED MULTIFIBER PROBES; FLUORESCENCE SPECTROSCOPY;

FIBER OPTICS;

EID: 0345714612     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.476141     Document Type: Conference Paper

References (17)

1. T. J. Pfefer, K. T. Schomacker, M. N. Ediger, and N. S. Nishioka, "Light propagation in tissue during fluorescence spectroscopy with single-fiber probes," IEEE Journal of Selected Topics in Quantum Electronics 7, 1004-1012 (2001).
2. T. J. Pfefer, K. T. Schomacker, M. N. Ediger, and N. S. Nishioka, "Multiple-fiber probe design for fluorescence spectroscopy in tissue," Applied Optics 41, 4712-4721 (2002).
3. U. Utzinger, R.R. Richards-Kortum, "Fiber optic probes for biomedical optical spectroscopy," Journal Biomedical Optics 8(1), 121-147, 2003.
4. N. Ramanujam, M. F. Mitchell, A. Mahadevan, S. Warren, S. Thomsen, E. Silva, and R. Richardskortum, "In-Vivo Diagnosis of Cervical Intraepithelial Neoplasia Using 337-Nm-Excited Laser-Induced Fluorescence," Proceedings of the National Academy of Sciences of the United States of America 91, 10193-10197 (1994).
5. M. G. Shim, B. C. Wilson, E. Marple, and M. Wach, "Study of fiber-optic probes for in vivo medical Raman spectroscopy," Applied Spectroscopy 53, 619-627 (1999).
6. B. W. Pogue and G. Burke, "Fiber-optic bundle design for quantitative fluorescence measurement from tissue," Applied Optics 37, 7429-7436 (1998).
7. M. Canpolat and J. R. Mourant, "Monitoring photosensitizer concentration by use of a fiber- optic probe with a small source-detector separation," Applied Optics 39, 6508-6514 (2000).
8. S. P. Lin, L. H. Wang, S. L. Jacques, and F. K. Tittel, "Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry," Applied Optics 36, 136-143 (1997).
9. J. R. Mourant, I. J. Bigio, D. A. Jack, T. M. Johnson, and H. D. Miller, "Measuring absorption coefficients in small volumes of highly scattering media: Source-detector separations for which path lengths do not depend on scattering properties," Applied Optics 36, 5655-5661 (1997).
10. T. Joshua Pfefer, L. Stephanie Matchette, Amanda M. Ross, and Marwood N. Ediger, "Selective detection of fluorophore layers in turbid media: the role of fiber-optic probe design," Optics Letters, 28(2), 120-122, (2003).
11. L. Marcu, J. M. Maarek, M. Fishbein, and W. S. Grundfest, "Arterial lesions characterization by time-resolved laser-induced fluorescence spectroscopy," Photochemistry and Photobiology 69, 69S (1999).
12. S.A. Prahl, M. Keijzer, S.L Jacques, A.J. Welch "A Monte Carlo Model of Light Propagation in Tissue". SPIE Proceedings IS 5, 102-111. 1989. Dosimetry of Laser Radiation in Medicine and Biology.
13. L. I. Grossweiner, J. L. Karagiannes, L. R. Jones, and P. W. Johnson, "Reflection and Transmission Coefficients in Plane-Parallel Layers with Refractive-Index Mismatch," Applied Optics 31, 106-109 (1992).
14. L. R. Jones and L. I. Grossweiner, "Singlet Oxygen Generation by Photofrin(R) in Homogeneous and Light-Scattering Media," Journal of Photochemistry and Photobiology B-Biology 26, 249-256 (1994).
15. T. F. Cooney, H. T. Skinner, and S. M. Angel, "Comparative study of some fiber-optic remote Raman probe design .2. Tests of single-fiber, lensed, and flat- and bevel- tip multi-fiber probes," Applied Spectroscopy 50, 849-860 (1996).
16. T. F. Cooney, H. T. Skinner, and S. M. Angel, "Comparative study of some fiber-optic remote Raman probe deesign .1. Model for liquids and transparent solids," Applied Spectroscopy 50, 836-848 (1996).
17. L. Quan and N. Ramanujam, "Relationship between depth of a target in a turbid medium and fluorescence measured by a variable-aperture method," Optics Letters 27, 104-106 (2002).