Humoral versus neural pathways for fever production in rats after administration of lipopolysaccharide

Journal of Trauma - Injury, Infection and Critical Care

Volumn 47, Issue 1, 1999, Pages 120-129

  Caldwell, Fred T ^a   Graves, Denise B ^a   Wallace, Bonny H ^a  

^a UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

Author keywords

Fever; Interleukin 6; Interleukin 1 ; Lipopolysaccharide; Tumor necrosis factor ; Vagus

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEVER; HUMORAL IMMUNITY; IMMUNOPATHOGENESIS; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SENSORY SYSTEM; TIME; VAGOTOMY;

EID: 0345711454     PISSN: 00225282     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005373-199907000-00025     Document Type: Article

References (24)

1. Blatteis CM, Bealer SL, Hunter WS, Llanos-QJ, Ahokas RA, Mashburn ITA. Suppression of fever after lesions of the anteroventral third ventricle in guinea pigs. Brain Res Bull. 1983;11:519-526.
2. Blatteis CM, Hales JRS, McKinley MJ, Fawcett AA. Role of the anteroventral third ventricle region in fever in sheep. Can J Physiol Pharmacol. 1987;65:1255-1260.
3. Caldwell FT, Graves DB, Wallace BH. Studies on the mechanism of fever following intravenous administration of endotoxin. J Trauma. 1998;44:304-312.
4. Hunter WS, Sehic E, Blatteis CM. Fever and the organum vasculosum laminae terminalis: another look. In: Milton AS, ed. Temperature Regulation, Advances in Pharmacological Sciences. Basel: Birkhauser Verlag; 1994:275-279.
5. Sehic E, Blatteis CM. Blockade of lipopolysaccharide-induced fever by subdiaphragmatic vagotomy in guinea pigs. Brain Res. 1996;726:160-166.
6. Romanovsky AA, Simons CT, Szekely M, Kulchitsky VA. The vagus nerve in the thermoregulatory response to systemic inflammation. Am J Physiol. 1997;273:R407-R413.
7. Caldwell FT, Graves DB, Wallace BH. Pathogenesis of fever in a rat burn model: the role of cytokines and lipopolysaccharide. J Burn Care Rehabil. 1997;18:525-530.
8. Cody RP, Smith JK. Applied Statistics and the SAS Programming Language. 3rd ed. North Holland, New York: Elsevier Science Publishing Co; 1991.
9. LeMay LG, Otterness IG, Vander AJ, Kluger MJ. In vivo evidence that the rise in plasma IL-6 following injection of a fever-inducing dose of LPS is mediated by IL-1β. Cytokine. 1990;2:199-204.
10. LeMay LG, Vander AJ, Kluger MJ. Role of interleukin-6 in fever in rats. Am J Physiol. 1990;258:R798-R803.
11. Givalos L, Dornand J, Mekaouche M, et al. Temporal cascade of plasma level surges in ACTH, corticosterone and cytokines in endotoxin-challenged rats. Am J Physiol. 1994; 266:R164-R170.
12. Lenczowski MJP, Van Dam A-M, Poole S, Larrick JW, Tilders FJH. Role of circulating endotoxin and interleukin-6 in the ACTH and corticosterone response to intraperitoneal LPS. Am J Physiol. 1997;273:R1870-R1877.
13. Jansky' L, Vybiral S, Pospisilova D, et al. Production of systemic and hypothalamic cytokines during the early phase of endotoxin fever. Neuroendocrinology. 1995;62:55-61.
14. Roth J, Conn CA, Kluger MJ, Zeisberger E. Kinetics of systemic and intra hypothalamic IL-6 and tumor necrosis factor during endotoxin fever in guinea pigs. Am J Physiol. 1993;265:R653-R658.
15. Blatteis CM, Sehic E. How may circulating pyrogens signal the brain? Neuro Physiol Sci. 1997;12:1-8.
16. Long NC, Morimoto A, Nakamori T, Murakami N. The effect of physical restraint on IL-1β and LPS-induced fever. Physiol Behav. 1991;50:625-628.
17. Wan W, Wetmore L, Sorensen CM, Greenberg AH, Nance DM. Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain. Brain Res Bull. 1994;34:7-14.
18. Watkins LR, Goehler LE, Relton JK, et al. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neurosci Lett. 1995;183:27-31.
19. Watkins LR, Wiertelak EP, Goehler LE, et al. Neurocircuitry of illness-induced hyperalgesia. Brain Res. 1994;639:283-299.
20. Bluthe' RM, Walter V, Porriet P, et al. Lipopolysaccharide induces sickness behavior in rats by a vagal mediated mechanism. C R Acad Sci III. 1994;317:499-503.
21. Gaykema RPA, Dijkstra I, Tilders FJH. Subdiaphragmatic vagotomy suppresses endotoxin-induced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion. Endocrinology. 1995;136:4717-4720.
22. Dantzer R. How do cytokines say hello to the brain? Neural versus humoral mediation. Eur Cytokine Netw. 1994;5:271-273.
23. Sawchenko PE, Cunningham ET Jr, Bittencourt JC, Chan RKW. Aminergic and peptidergic pathways subserving the stress response. In: Kvetnansky R, McCarty R, Axelrod J, eds. Stress: Neuroendocrine and molecular approaches. New York: Gordon and Breach Science Publishers; 1992:15-27.
24. Elmquist JK, Scammell TE, Jacobson CD, Saper CB. Distribution of fos-like immunoreactivity in the rat brain following intravenous lipopolysaccharide administration. J Comp Neurol. 1996;371:85-103.