Platelet activation in patients with chronic hepatitis C

Tokai Journal of Experimental and Clinical Medicine

Volumn 27, Issue 4, 2002, Pages 101-106

  Fusegawa, Hisae ^a   Shiraishi, Koichi ^a   Ogasawara, Fusao ^a   Shimizu, Mie ^a   Haruki, Yasuo ^a   Miyachi, Hayato ^a   Matsuzaki, Shohei ^a   Ando, Yasuhiko ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chronic hepatitis C; Liver fibrosis; Platelet activation; Platelet microparticles

Indexed keywords

ACTIVATION DEPENDENT MONOCLONAL ANTIBODY; HYALURONIC ACID; MONOCLONAL ANTIBODY; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD CLOTTING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ECHOGRAPHY; FEMALE; FIBRINOLYSIS; FLOW CYTOMETRY; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; PLATELET MICROPARTICLE; SCORING SYSTEM; SHEAR STRESS; SPLEEN SIZE; STAINING; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT; THROMBOCYTOPENIA; VIRUS HEPATITIS;

ADULT; AGED; AGED, 80 AND OVER; BLOOD COAGULATION; BLOOD PLATELETS; FEMALE; FIBRINOLYSIS; HEPATITIS B, CHRONIC; HEPATITIS C, CHRONIC; HUMANS; HYALURONIC ACID; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PARTICLE SIZE; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PLATELET COUNT; PROCOLLAGEN; REFERENCE VALUES;

EID: 0345700666     PISSN: 03850005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Adnolfi LE, Grazia M, Andreana A et al. Hepatic fibrosis plays a central role in the pathogenesis of thrombocytopenia in patients with chronic viral hepatitis. Br J Haematology. 2001, 113, 590-595.
2. Nagamine T, Ohtuka T, Takehara K et al. Thrombocytopenia associated with hepatic C viral infection. J Hepatology. 1996, 24, 135-140.
3. Koruk M, Onuk MD, Akcay F, Savas MC. Serum thrombopoietin levels in patients with chronic hepatitis and liver cirrhosis, and its relationship with circulating thrombocyte counts. Hepatogastroenterology. 2002, 49, 1645-1648.
4. Murawaki Y, Koda M, Okamoto K, Mimura K, Kawasaki H, Diagnostic value of serum type IV collagen test in comparison with platelet count for predicting the fibrotic stage in patients with chronic hepatitis. J Gastroentrol Hepatol. 2001, 16, 777-781.
5. Pohl A, Behling C, Oliver D et al. Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection. Am J Gastroenterol? 2001, 96, 3053-3055.
6. Desmet VJ, Gerber M, Hoofnagel et al. Clacification of chronic hepatitis: diagnosis, grading and staging. Hepatology. 1994, 19, 1513-1520.
7. Nomura S, Komiyama Y, Miyake T et al. Amyloid β-protein precursor-rich platelet microparticles in thrombotic disease. Thromb Haemost. 1994, 72, 519-522
8. Omoto S, Nomura S, Shouzu A et al. Detection of monocyte-derived microparticles in patient with type II diabetes mellitus. Diabetologia. 2002, 45, 550-555.
9. Matunami S, Kimura K, Ohto M, et al. Ultrasonography in the diagnosis of portal hypertension. In: Okuda K, ed. Portal hypertension clinical and physiological aspect. Tokyo: Springer-Verlag, 1991, 197-206.
10. Miyazaki Y, Nomura S, Mitake T et al. High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles. Blood. 1996, 88, 3456-3464.
11. Wench JY, Lawrence LH, Manuel A. Clinical significance of platelet microparticles in autoimmune thrombocytopenias. J Lab Clin Med. 1992, 119, 334-345.
12. Osumi K, Ozeki Y, Saito S, et al. Development and assessment of enzyme immunoassay for platelet-derived microparticles. Thromb Haemost. 2001, 85, 326-330.
13. Sebatier F, Darmon P, Hugel B et al. Type 1 and type 2 diabetic patients display different patterns of cellular microparticles. Diabetes. 2002, 51, 2840-2845.
14. Lee YJ, Horstman LL, Janania J et al. Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias. Thromb Res. 1996, 72, 295-304.
15. Ferroni P, Mammarella A, Martini F et al. Increased soluble P-selectin levels in hepatitis C virus-related chronic hepatitis: correlation with viral load. J Inv Med. 2001, 49, 407-412.
16. Schaffner F and Popper H. Capillarization of hepatic sinusoids in man. Gastroenterology. 1963, 44, 239-242.
17. Eriksson S, Fraser JRE, Laurent TC, Pertoft H, Smedsrod B. Endothelial cells are a site of uptake and degradation of hyaluronic acid in the liver. Exp Cell Res, 1983, 144, 223-228.
18. Smedsrod B, Pertoft H, Erikson S, Fraser RE, Laurent TC. Studies in vitro on the uptake and degradation of sodium hyaluronate in rat liver endothelial cells. Biochem J. 1984, 223, 617-626.
19. Fraser JRE, Alcom D, Laurent TC, Robinson AD, Ryan GB. Uptake of circulating hyaluronic acid by the rat liver: Cellular localization in situ. Cell Tissue Res. 1985, 242, 505-510.
20. MacGary CT, Raja RH, Weigel PH. Endocytosis of hyaluronic acid by rat liver endothelial cell: Evidence for receptor recycling. Biochem J. 1989, 8, 141-146.
21. Ueno T, Inuzuka S, Torimura T. Serum hyaluronate reflects hepatic sinusoidal capillarization. Gastroenterology. 1993, 105, 475-481.
22. Wanless LR, Belglyne J, Huet P. Hepatic sinusoidal fibrosis induced by cholesterol and stilbestrol in the rabbit: 1. morphology and inhibition of fibrosis by dipyridamole. Hepatology. 1996, 24, 855-863.
23. Kage M, Shimamatu K, Nakashima E et al. Long-term evolution of fibrosis from chronic hepatitis to cirrhosis in patients with hepatitis C: morphometric analysis of repeated biopsies. Hepatology. 1997, 25, 1028-1031.