Manipulating transmitter release at the neuromuscular junction of neonatal rats alters the expression of ChAT and GAP-43 in motoneurons

Developmental Brain Research

Volumn 146, Issue 1-2, 2003, Pages 29-38

  Sharp, Paul S ^a   Dekkers, Joanna ^a   Dick, James R T ^a   Greensmith, Linda ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Acetylcholine; Growth; Neuromuscular interaction; Postnatal development

Indexed keywords

4 AMINOPYRIDINE; CHOLINE ACETYLTRANSFERASE; MAGNESIUM SULFATE; NEUROMODULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNORADIOMETRIC ASSAY; MOTOR DEVELOPMENT; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NERVE CELL LESION; NERVE ENDING; NERVE INJURY; NEUROMUSCULAR SYNAPSE; NEUROMUSCULAR TRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; SCIATIC NERVE; SOLEUS MUSCLE;

EID: 0345690160     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devbrainres.2003.09.005     Document Type: Article

References (42)

1. Benowitz L.I., Routtenberg A. GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci. 20:1997;84-91.
2. Burt A.M. Choline acetyltransferase and acetylcholinesterase in the developing rat spinal cord. Exp. Neurol. 47:1975;173-180.
3. Caroni P., Becker M. The downregulation of growth-associated proteins in motoneurons at the onset of synapse elimination is controlled by muscle activity and IGF1. J. Neurosci. 12:1992;3849-3861.
4. Chow I., Poo M.M. Release of acetylcholine from embryonic neurons upon contact with muscle cell. J. Neurosci. 5:1985;1076-1082.
5. Connold A.L., Greensmith L., Tyc F., Vrbová G. A simple method for local delivery of various substances to the rat neuromuscular system. Brain Res. Brain Res. Protoc. 1:1997;79-82.
6. Cooke J.D., Okamoto K., Quastel D.M. The role of calcium in depolarization-secretion coupling at the motor nerve terminal. J. Physiol. (Lond.). 228:1973;459-497.
7. Dekkers J., Navarrete R. Persistence of somatic and dendritic growth associated processes and induction of dendritic sprouting in motoneurones after neonatal axotomy in the rat. NeuroReport. 9:1998;1523-1527.
8. Del Castillo J., Katz B. The effect of magnesium on the activity of motor nerve endings. J. Physiol. 124:1954;553-559.
9. Fonnum F. A rapid radiochemical method for the determination of choline acetyltransferase. J. Neurochem. 24:1975;407-409.
10. Greensmith L., Vrbová G. Alterations of nerve-muscle interaction during postnatal development influence motoneurone survival in rats. Brain Res. Dev. Brain Res. 69:1992;125-131.
11. Greensmith L., Vrbová G. Motoneurone survival: a functional approach. Trends Neurosci. 19:1996;450-455.
12. Greensmith L., Dick J., Emanuel A.O., Vrbová G. Induction of transmitter release at the neuromuscular junction prevents motoneuron death after axotomy in neonatal rats. Neuroscience. 71:1996;213-220.
13. Greensmith L., Ng P., Mohaghegh P., Vrbová G. Reducing transmitter release from nerve terminals influences motoneuron survival in developing rats. Neuroscience. 97:2000;357-362.
14. Grimaldi M., Atzori M., Ray P., Alkon D.L. Mobilization of calcium from intracellular stores, potentiation of neurotransmitter-induced calcium transients, and capacitative calcium entry by 4-aminopyridine. J. Neurosci. 21:2001;3135-3143.
15. Hanker J.S., Yates P.E., Metz C.B., Rustioni A. A new specific, sensitive and non-carcinogenic reagent for the demonstration of horseradish peroxidase. Histochem. J. 9:1977;789-792.
16. Henderson C.E., Camu W., Mettling C., Gouin A., Poulsen K., Karihaloo M., Rullamas J., Evans T., McMahon S.B., Armanini M.P. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature. 363:1993;266-270.
17. Katz B., Miledi R. Tetrodotoxin-resistant electric activity in presynaptic terminals. J. Physiol. (Lond.). 203:1969;459-487.
18. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
19. Lowrie M.B., Krishnan S., Vrbová G. Recovery of slow and fast muscles following nerve injury during early post-natal development in the rat. J. Physiol. (Lond.). 331:1982;51-66.
20. Lowrie M.B., O'Brien R.A., Vrbova G. The effect of altered peripheral field on motoneurone function in developing rat soleus muscles. J. Physiol. 368:1985 (Nov.);513-524.
21. Lowrie M.B., Krishnan S., Vrbová G. Permanent changes in muscle and motoneurones induced by nerve injury during a critical period of development of the rat. Brain Res. 428:1987;91-101.
22. Lundh H., Thesleff S. The mode of action of 4-aminopyridine and guanidine on transmitter release from motor nerve terminals. Eur. J. Pharmacol. 42:1977;411-412.
23. Muller D. Potentiation by 4-aminopyridine of quantal acetylcholine release at the Torpedo nerve-electroplaque junction. J. Physiol. (Lond.). 379:1986;479-493.
24. Navarrete R., Vrbová G. Changes of activity patterns in slow and fast muscles during postnatal development. Dev. Brain Res. 8:1983;11-19.
25. O'Brien R.A., Vrbová G. Acetylcholine synthesis in nerve endings to slow and fast muscles of developing chicks: effect of muscle activity. Neuroscience. 3:1978;1227-1230.
26. O'Brien R.A., Ostberg A.J., Vrbová G. Observations on the elimination of polyneuronal innervation in developing mammalian skeletal muscle. J. Physiol. 282:1978;571-582.
27. Phelps P.E., Barber R.P., Houser C.R., Crawford G.D., Salvaterra P.M., Vaughn J.E. Postnatal development of neurons containing choline acetyltransferase in rat spinal cord: an immunocytochemical study. J. Comp. Neurol. 229:1984;347-361.
28. Piehl F., Hammarberg H., Hokfelt T., Cullheim S. Regulatory effects of trophic factors on expression and distribution of CGRP and GAP-43 in rat motoneurons. J. Neurosci. Res. 51:1998;1-14.
29. Poo M.M. Neurotrophins as synaptic modulators. Nat. Rev., Neurosci. 2:2001;24-32.
30. Romanes G. Motor localization and the effects of nerve injury on the ventral horn cells of the spinal cord. J. Anat. 80:1946;11-131.
31. Schmalbruch H. Motoneuron death after sciatic nerve section in newborn rats. J. Comp. Neurol. 224:1984;252-258.
32. Sendtner M., Holtmann B., Kolbeck R., Thoenen H., Barde Y.A. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature. 360:1992;757-759.
33. Skene J.H., Willard M. Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems. J. Cell Biol. 89:1981;96-103.
34. Skene J.H., Virag I. Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43. J. Cell Biol. 108:1989;613-624.
35. Skene J.H., Jacobson R.D., Snipes G.J., McGuire C.B., Norden J.J., Freeman J.A. A protein induced during nerve growth (GAP-43) is a major component of growth-cone membranes. Science. 233:1986;783-786.
36. Thesleff S. Aminopyridines and synaptic transmission. Neuroscience. 5:1980;1413-1419.
37. Wang X.X., Butowt R., Vasko M.R., von Bartheld C.S. Mechanisms of release of antrogradely transported neurotrophin-3 from axon terminals. J. Neurosci. 22:2002;931-945.
38. White C.M., Greensmith L., Vrbová G. Repeated stimuli for axonal growth causes motoneuron death in adult rats: the effect of botulinum toxin followed by partial denervation. Neuroscience. 95:2000;1101-1109.
39. Wong V., Arriaga R., Ip N.Y., Lindsay R.M. The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motorneurons. Eur. J. Neurosci. 5:1993;466-474.
40. Wong K.C., Meyer T., Harding D.I., Dick J.R., Vrbová G., Greensmith L. Integrins at the neuromuscular junction are important for motoneuron survival. Eur. J. Neurosci. 11:1999;3287-3292.
41. Xie Z.P., Poo M.M. Initial events in the formation of neuromuscular synapse: rapid induction of acetylcholine release from embryonic neuron. Proc. Natl. Acad. Sci. U. S. A. 83:1986;7069-7073.
42. Yan Q., Elliott J., Snider W.D. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death. Nature. 360:1992;753-755.