Triacylglycerol, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol isolated from bovine udder and its synthetic enantiomer can potentiate the mitogenic activity for mouse peritoneal macrophages

Cellular Physiology and Biochemistry

Volumn 13, Issue 6, 2003, Pages 415-422

  Suh, Jeong S ^c   Kwon, Jin ^b   Eun, Jae S ^b   Lee, Yun J ^a   Limb, Jin K ^a   Ko, Soo Y ^a   Han, So Y ^a   Bae, Yun S ^a   Jhon, Gil Ja ^a  

^a Ewha Womans University   (South Korea)

^b Woosuk University   (South Korea)

^c Jeonju Kijeon College   (South Korea)

Author keywords

1 Palmitoyl 2 linoleoyl 3 acetyl rac glycerol; Granulocyte macrophage colony stimulating factor; Peritoneal macrophage; Protein kinase C; Reactive oxygen species

Indexed keywords

1 PALMITOYL 2 LINOLEOYL 3 ACETYLGLYCEROL; ACETYLCYSTEINE; CALPHOSTIN C; GLYCEROL DERIVATIVE; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATTLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENANTIOMER; ENZYME ACTIVITY; INHIBITION KINETICS; MALE; MITOGENESIS; MOUSE; MOUSE STRAIN; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

BOVINAE;

EID: 0345689348     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075129     Document Type: Article

References (36)

1. 2+ and glycerol 3-phosphate on the esterification of fatty acids synthesized de novo. Biochem J 1984;220:513-519.
2. Myher JJ, Kuksis A, Marai L: Identification of the more complex triglycerols in bovine milk fat by gas chromatography-mass spectrometry using polar capillary columns. J Chromatogr 1988;452:93-118.
3. Kaufmann HP, Keller M: Chem Ber 1948;81:152.
4. Kleiman R, Miller RW, Earle FR, Wolff LA: (S)-1,2-Diacyl-3-acetins: Optically active triglycerides from Euonymus verrucosus seed oil. Lipids 1967;2:473-478.
5. Bagby MO, Smith Jr CR: Asymmetric triglycerides from Impatiens edgeworthii seed oil. Biochim Biophys Acta 1967;137:475-477.
6. Lhim JK, Kim YH, Han SY, Jhon GJ: Isolation and characterization of monoacetyldiglycerides from bovine udder. J Lipid Res 1999;40:2169-2176.
7. Kim YH, Han SY, Cho SH, Yoo JS, Jhon GJ: Structural determination of synthetic monoacetyldiglycerides by tandem mass spectrometry of sodium adducted molecular ions. Rapid Commun Mass Spec 1999;13:481-487.
8. 2+ mobilizing agents in rat pancreatic acinal cells. Biorog Med Chem Lett 1999;9:59-64.
9. Sordillo LM, Shafer-Weaver K, DeRosa D: Immunology of the mammary gland. J Dairy Sci 1997;80:1851-1865.
10. Paape MJ, Shafer-Weaver K, Capuco AV, Van Oostveldt K, Burvenich C: Immune surveillance of mammary tissue by phagocytic cells. Adv Exp Med Biol 2000;480:259-277.
11. Rhee SG, Bae YS, Lee SR, Kwon J: Hydrogen peroxide: A key messenger that modulates protein phosphorylation through cysteine oxidation. Science's stke perspective 2000.
12. Bae YS, Kang SW, Seo MS, Baines IC, Tekel E, Chock PB, Rhee SG: Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation. J Biol Chem 1997;272: 217-221.
13. Sattler M, Winkler T, Verma S, Byrne CH, Shrikhande G, Salgia R, Griffin JD: Hematopoietic growth factors signal through the formation of reactive oxygen species. Blood 1999;93:2928-2935.
14. 2 generating system present in human fat-cell plasma membranes is multireceptor-linked and under antagonistic control by hormones and cytokines. Biochem J 1995;307:543-548.
15. 2 . Proc Natl Acad Sci USA;94:11233-11237.
16. Suzuki YJ, Forman HJ, Sevanian A: Oxidants as stimulators of signal transduction. Free Radical Biol Med 1997;22:269-285.
17. Jacobson M: Reactive oxygen species and programmed cell death. Trends Biochem Sci 1996;21:83-86.
18. Lee SR, Kwon KS, Kim SR, Rhee SG: Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J Biol Chem 1998;273:15366-15372.
19. Kourie JI: Interaction of reactive oxygen species with ion transport mechanisms. Am J Physiol 1998;275:C1-C24.
20. Kusuhara M, Chait A, Cader A, Berk BC: Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages. Arteriscler Thromb Vasc Biol 1997;17:141-148.
21. Claus R, Fyrnys B, Deigner HP, Wolf G: Oxidized low-density lipoprotein stimulates protein kinase C (PKC) and induces expression of PKC-isotopes via prostaglandin-H-synthase in P388D1 macrophage-like cells. Biochemistry 1996;35:4911-4922.
22. Miki S, Tsukada S, Nakamura Y, Aimoto S, Hojo H, Sato B, Yamamoto M, Miki Y: Functional and possible physical association of scavenger receptor with cytoplasmic tyrosine kinase Lyn in monocytic THP-1-derived macrophages. FEBS Lett 1996;399:241-244.
23. Burgos CE, Ayer DE, Johnson RA: A new, asymmetric synthesis of lipids and phospholipids. J Org Chem 1987;52:4973.
24. Jhon EC, Ada MK, David M, Ethan MS, Warren S: Current Protocols in Immunology: Wiley Interscience A, 1991;Vol I: 3.5-3.7.
25. Mosmann T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
26. Kotnic V, Jr Fleischmann WR: A simple and rapid method to determine hematopoietic growth factor activity. J Immunol Methods 1990;129:23-30.
27. Scudiero DA, Shoemaker RH, Paull KD, Monks A, Tierney S, Nofziger TH, Currens MJ, Seniff D, Boyd MR: Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 1988;48:4827-4833.
28. Martens JS, Reiner NE, Herrera-Velit P, Steinbrecher U P: Phosphatidylinositol 3-kinase is involved in the induction of macrophage growth by oxidized low density lipoprotein. J Biol Chem 1998;273:4915-4920.
29. Sakai M, Miyazaki A, Hakamata H, Sato Y, Matsumura T, Kobori S, Shichiri M, Horiuchi S: Lysophosphatidylcholine potentiates the mitogenic activity of modified LDL for human monocyte-derived macrophages. Arterioscler Thromb Biol 1996;16:600-605.
30. Bass DA, Parce JW, Dechatelet LR, Szejda P, Seeds MC, Thomas M: Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol 1983;130:1910-1917.
31. Matsumura T, Sakai M, Kobori S, Biwa T, Takemura T, Matsuda H, Hakamata H, Horiuchi S, Shichiri M: Two intracellular signaling pathways for activation of protein kinase C are involved in oxidized low-density lipoprotein-induced macrophage growth. Arteriscler Thromb Vasc Biol 1997;17:3013-3020.
32. Cross AR, Jones OT: Enzymic mechanisms of superoxide production. Biochim Biophys Acta 1991;057:281-298.
33. Valledor AF, Comalada M, Xaus J, Celada A: The differential time-course of extracellular-regurated kinase activity correlates with the macrophage response toward proliferation or activation. J Biol Chem 2000;275:7403-7409.
34. Celada A, Nathan C: Macrophage activation revisited. Immunol Today 1994;15:100-102.
35. 2 production requires the activation of phosphatidylinositol 3-kinase. J Biol Chem 2000;275:10527-10531.
36. Wientjes FB, Segal AW: NADPH oxidase and the respiratory burst. Semin Cell Biol 1995;6:357-365.