Renin similar to the submaxillary gland form is expressed in mouse mesangial cells: Subcellular localization and AII generation under control and glucose-stimulated conditions

Cellular Physiology and Biochemistry

Volumn 13, Issue 6, 2003, Pages 357-366

  Leite, Cleber A ^a   Cristovam, Priscila C ^a   Leitão, Aurilucia A ^a   Miranda, Antonio ^a   Andrade, Maria Claudina ^a   Di Marco, Giovanna ^a   Casarini, Dulce E ^a   Boim, Mirian A ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Angiotensin II; Diabetic nephropathy; Glucose; Mouse mesangial cells; Renin; Submaxillary gland

Indexed keywords

GLUCOSE; PRORENIN; RENIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL LYSATE; CELL NUCLEUS; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; MESANGIUM CELL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY; SUBMANDIBULAR GLAND;

EID: 0345689347     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000075123     Document Type: Article

References (43)

1. Johnston CI, Fabris B & Jandeleit K. Intrarenal renin-angiotensin system in renal physiology and pathophysiology. Kidney Int 1993;44:S59-S63.
2. Lai KN, Leung JCK, Lai KB, To WY, Yeung VTF, Mac-Moune Lai F. Gene expression of the renin-angiotensin system in human kidney. J Hypertens 1998;16:91-102.
3. Casarini DE, Boim MA, Stella RC, Krieger-Azzolini MH, Krieger JE, Schor N. Angiotensin I-converting enzyme activity in tubular fluid along the rat nephron. Am J Physiol 1997;272:F405-409.
4. Moe OW, Ujiie R, Miller RT, Widell J, Alpern RJ, Henrich WL. Renin expression in renal proximal tubule. J Clin Invest 1993;91:774-779.
5. Ingelfinger JR, Pratt RE, Ellison K, Dzau VJ. Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. J Clin Invest 1986;78:1311-1315.
6. Reudelhuber TL: Molecular biology of renin, in Molecular Nephrology, edited by Detlef Schlondorff, Joseph V. Bonventre, New York, Basel, Hong Kong 1995, pp 71-89.
7. Andrade AQ, Casarini DE, Schor N, Boim MA. Characterization of renin mRNA expression and enzyme activity in rat and mouse mesangial cells. Braz J Med Biol Res 2002;35:17-24.
8. Andrade MC, Quinto BM, Carmona AK, Ribas OS, Boim MA, Schor N, Casarini DE. Purification and characterization of angiotensin-I converting enzymes from mesangial cells in culture. J Hypertens 1998;16:2063-2074.
9. Chansel D, Dussaule JC, Ardaillou N, Ardaillou R. Identification and regulation of renin in human cultured mesangial cells. Am J Physiol 1987;252:32-38.
10. Leehey DJ, Singh AK, Alavi N, Singh R. Role of angiotensin II in diabetic nephropathy. Kidney Int 2000;77:93-98.
11. Kohzuki M, Yasujima M, Kanazawa M, Yoshida K, Fu LP, Obara K, Saito T, Abe K. Antihypertensive and renal-protective effects of losartan in streptozotocin diabetic rats. J Hypertens 1995;13:97-103.
12. Price DA, Porter LE, Gordon M, Fisher ND, De'Oliveira JM, Laffel LM, Passan DR, Williams GH, Hollenberg NK. The paradox of the low-renin state in diabetic nephropathy. J Am Soc Nephrol 1999;10:2382-2391.
13. Andreson S, Jung FF, Ingelfinger JR. Renal renin angiotensin system in diabetes: Functional immunohistochemical, and molecular biological correlations. Am J Physiol 1993;265:F477-F486.
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
15. Singh R, Alavi N, Singh AK, Leehey J. Role of angiotensin II in glucose-induced inhibition of mesangial matrix degradation. Diabetes 1999;48:2066-2073.
16. Menard J, Bews J, Heusser C. A multirange ELISA for the measurement of plasma renin in humans and primates. J Hypertens 1984;:S275-278.
17. Day RP, Morris BJ. Properties of inactive renin in human plasma. Clin Exp Pharmacol Physiol 1979;6:611-624.
18. Boyd GW. A protein-bound form of porcine renal renin. Circ Res 1974;35:426-438.
19. Shenoy U, Cassis L. Characterization of renin activity in brown adipose tissue. Am J Physiol 1997;272:C989-999.
20. Takahashi S, Ohsawa T, Miura R, Miyake Y. Purification of high molecular weight (HMW) renin from porcine kidney and direct evidence that the HMW renin is a complex of renin with renin binding protein (RnBP). J Biochem 1983;93:265-274.
21. Takahashi S, Inoue H, Fukui K, Miyake Y. Structure and function of renin binding protein. Kidney Int 1994;46:1525-1527.
22. Takahashi S, Kumagai M, Shindo S, Saito K, Kawamura Y. Renin inhibits N-acetyl-D-glucosamine 2-epimerase (renin-biding-protein). J Biochem (Tokyo) 2000;28:951-956.
23. Schmitz C, Gotthardt M, Hinderlich S, Leheste JR, Gross V, Vorum H, Christensen EI, Luft FC, Takahashi S, Willnow TE. Normal blood pressure and plasma renin activity in mice lacking the renin-binding protein, a cellular renin inhibitor. J Biol Chem 2000;75:15357-15362.
24. Murakami K, Takahashi S, Hirose S, Takii Y, Inagami T. Renin precursor and its activation mechanism in hog kidney. Clin Sci (Lond) 1980;59:21s-24s.
25. Lee-Kirsch MA, Gaudet F, Cardoso MC, Lindpaintner K. Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing. Circ Res 1999;84:240-246.
26. Field LJ, McGowan RA, Dickinson DP, Gross KW. Tissue and gene specificity of mouse renin expression. Hypertension 1984;6:597-603.
27. Panthier JJ, Foote S, Chambraud B, Strosberg AD, Corvol P, Rougeon F. Complete amino acid sequence and maturation of the mouse submaxillary gland renin precursor. Nature 1982;298:90-92.
28. Panthier JJ, Dreyfus M, Roux TL, Rougeon F. Mouse kidney and submaxillary gland renin genes differ in their 5′ putative regulatory sequences. Proc Natl Acad Sci (USA) 1984;81:5489-5493.
29. Sigmund CD, Gross KW. Structure, expression, and regulation of the murine renin genes. Hypertension 1991;18:446-457.
30. Wilson CM, Taylor BA. Genetic regulation of thermostability of mouse submaxillary gland renin. J Biol Chem 1982;257:217-223.
31. Field LJ, Gross KW. Ren-1 and Ren-2 loci are expressed in mouse kidney. Proc Natl Acad Sci (USA) 1985;82:6196-6200.
32. Ladenheim RG, Seidah NG, Rougeon F. N-linked glycosylation affects the processing of mouse submaxillary gland prorenin in transfected AtT20 cells. Eur J Biochem 1991;198:535-540.
33. Wang Q, Hummler E, Nussberger J, Clement S, Gabbiani G, Brunner HR, Burnier M. Blood pressure, cardiac, and renal responses to salt and deoxycorticosterone acetate in mice: role of renin genes. J Am Soc Nephrol 2002;13:1509-1516.
34. Carey RM, McGrath E, Pentz ES, Gomez RA, Barret PQ. Biochemical coupling in renin-releasing cells. J Clin Invest 1997;100:1566-1574.
35. Vidotti DB, Cristovam PC, Casarini DE, Schor N, Boim MA. Effect of glucose on the activity of renin angiotensin system in rat primary mesangial cells. J Am Soc Nephrol 2002;13:534A.
36. van Kesteren CA, Danser AH, Derkx FH, Dekkers DH, Lamers JM, Saxena PR, Schalekamp MA. Mannose 6-phosphate receptor-mediated internalization and activation of prorenin by cardiac cells. Hypertension 1997;1389-1396.
37. Admiraal PJ, van Kesteren CA, Danser AH, Derkx FH, Sluiter W, Schalekamp MA. Uptake and proteolytic activation of prorenin by cultured human endothelial cells. J Hypertens 1999;17:621-9.
38. Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002;109:1417-1427.
39. Nguyen G, Delarue F, Berrou J, Rondeau E, Sraer JD. Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int 1996;50:1897-903.
40. Re RN, MacPhee AA, Fallon JT. Specific nuclear binding of angiotensin II by rat liver and spleen nuclei. Clin Sci (Lond) 1981;61:245s-247s.
41. Erdmann B, Fuxe K, Ganten D. Subcellular localization of angiotensin II immunoreactivity in the rat cerebellar cortex. Hypertension 1996;28:818-24.
42. Booz GW, Conrad KM, Hess AL, Singer HA, Baker KM. Angiotensin-II-binding sites on hepatocyte nuclei. Endocrinology 1992;130:3641-3649.
43. Eggena P, Zhu JH, Sereevinyayut S, Giordani M, Clegg K, Andersen PC, Hyun P, Barrett JD. Hepatic angiotensin II nuclear receptors and transcription of growth-related factors. J Hypertens 1996;14:961-8.