Structural changes to ribonuclease A and their effects on biological activity

Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology

Volumn 123, Issue 2, 1999, Pages 103-111

  Souček, Josef ^a   Raines, Ronald T ^b   Haugg, Monika ^c   Raillard Yoon, Sun Ai ^c   Benner, Steven A ^c,d  

^a INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c ETH ZURICH   (Switzerland)

^d University of Florida ^*  (United States)

Author keywords

Antitumor action; Bovine seminal ribonuclease; Immunosuppression; Ribonuclease variants; Structure

Indexed keywords

AMINO ACID; HYBRID PROTEIN; ISOENZYME; RIBONUCLEASE A;

AMINO ACID COMPOSITION; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CATTLE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; LYMPHOCYTE; MIXED LEUKOCYTE CULTURE; MUTANT; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN VARIANT; SEMINAL PLASMA;

NON-PROGRAMMATIC;

ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; CELL DIVISION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; K562 CELLS; LYMPHOCYTES; MUTATION; PROTEIN CONFORMATION; RIBONUCLEASE, PANCREATIC;

EID: 0345643469     PISSN: 07428413     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0742-8413(99)00005-5     Document Type: Article

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