Identification of peptide mimotopes for the fluorescein hapten binding of monoclonal antibody B13-DE1

Journal of Molecular Recognition

Volumn 12, Issue 3, 1999, Pages 191-197

  Bottger V ^a,d   Peters, L E ^b   Micheel, B ^c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b InViTek GmbH   (Germany)

^c UNIVERSITY OF POTSDAM   (Germany)

^d Wilex Biotechnology GmbH   (Germany)

Author keywords

Antibodies; Fluorescein; Mimicry; Mimotopes; Peptides

Indexed keywords

AMINO ACID SEQUENCE; IMMUNIZATION; MONOCLONAL ANTIBODY; PROTEIN INTERACTION;

EID: 0345593798     PISSN: 09523499     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1352(199905/06)12:3<191::AID-JMR455>3.0.CO;2-2     Document Type: Article

References (41)

1. Balass, M., Heldman, Y., Cabilly, S., Givol, D., Katchalski-Katzir, E. and Fuchs, S. (1993) Identification of a hexapeptide that mimics a conformation-dependent binding site of acetylcholine receptor by use of a phage-epitope library. Proc. Natl Acad. Sci. USA 90, 10638-10642.
2. Böttger, V. and Lane, E. B. (1994) A monoclonal antibody epitope on keratin 8 identified using a phage peptide library. J. Mol. Biol. 235, 61-67.
3. Böttger, V., Böttger, A., Lane, E. B. and Spruce, B. A. (1995) Comprehensive epitope analysis of monoclonal anti-proenkephalin antibodies using phage display libraries and synthetic peptides: revelation of antibody fine specificities caused by somatic mutations in the variable region genes. J. Mol. Biol. 247, 932-946.
4. Cwirla, S. E., Peters, E. A., Barrett, R. W. and Dower, W. J. (1990) Peptides on phage: a vast library of peptides for identifying ligands. Proc. Nat Acad. Sci. USA 87, 6378-6382.
5. Daniels, D. A. and Lane, D. P. (1996) Phage peptide libraries. Methods 9, 494-507.
6. Davis, S. J., Schockmel, G. A., Somoza, C., Buck, D. W., Healey, D. G., Rieber, E. P., Reiter, C. and Williams, A. F. (1992) Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors. Nature 358, 76-79.
7. Devlin, J. J., Panganiban, L. C. and Devlin, P. E. (1990) Random peptide libraries: a source of specific protein binding molecules. Science 249, 404-406.
8. Felici, F., Castagnoli, L., Musacchio, A., Jappeli, R. and Cesarini, G. (1991) Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector. J. Mol. Biol. 222, 301-310.
9. Folgori, A., Tafi, R., Meola, A., Felici, F., Galfre, G., Cortese, R., Monaci, P. and Nicosia, A. (1994) A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO J. 13, 2236-2243.
10. Harmer, I. J. and Samuel, D. (1989) The FITC-anti-FITC system is a sensitive alternative to biotin-streptavidin in ELISA. J. Immunol. Meth. 122, 115-121.
11. Hoess, R., Brinkmann, U., Handel, T. and Pastan, I. (1993) Identification of a peptide which binds to the carbohydrate-specific monoclonal antibody B3. Gene 128, 43-49.
12. Hoess, R. H., Mack, A. J., Walton, H. and Reilly, T. M. (1994) Identification of a structural epitope by using a peptide library displayed on filamentous bacteriopnage. J. Immunol. 153, 724-729.
13. Hopp, T. P. and Woods, K. R. (1981) Prediction of protein antigenic determinants from amino acid sequences. Proc. Nat. Acad. Sci. USA 78, 3824-3828.
14. Iwasaki, Y., Takabatake, H., Shinji, T., Monestier, M. and Ferrone, S. (1994) Structural profile of idiotype, anti-idiotype and anti-anti-idiotype monoclonal antibodies in the HLA-DQ3 anti-genic system. Eur. J. Immunol. 24, 2874-2881.
15. Jantscheff, P., Böttger, V., Price, M., Micheel, B., Kaiser, G., Zotter, S., Kotzsch, M., Grossmann, H. and Karsten, U. (1991) Production and characterization of monoclonal antibodies against carcinoembryonic antigen (CEA). Biomed. Biochim. Acta 50, 1261-1267.
16. Keitel, T., Kramer, A., Wessner, H., Scholz, C., Schneider-Mergener, J. and Hohne, W. (1997) Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. Cell 91, 811-820.
17. Kramer, A., Keitel, T., Winkler, K., Stocklein, W., Hohne, W. and Schneider-Mergener, J. (1997) Molecular basis for the binding promiscuity of an anti-p24 (HIV-1) monoclonal antibody. Cell 91, 799-809.
18. Kooyman, D. L., McClellan, S. B., Parker, W., Avissar, P. L., Velardo, M. A., Platt, J. L and Logan, J. S. (1996) Identification and characterization of a galactosyl peptide mimetic. Implications for use in removing xenoreactive anti-A Gal antibodies. Transplantation 61, 851-855.
19. Larocca, D., Peterson, J. A. and Ceriani, R. L. (1992) High level expression in E. coli of an alternate reading frame of pS2 mRNA that encodes a mimotope of human breast epithelial mucin tandem repeat. Hybridoma 11, 191-201.
20. Lenstra, J. A., Erkens, J. H., Langeveld, J. G., Posthumus, W. P., Meloen, R. H., Gebauer, F., Correa, I., Enjuanes, L. and Stanley, K. K. (1992) Isolation of sequences from a random-sequence expression library that mimic viral epitopes. J. Immunol. Meth. 152, 149-157.
21. Lindner, W. and Robey, F. A. (1987) Automated synthesis and use of N-chloroacetyl-modified peptides for the preparation of synthetic peptide polymers and peptide-protein immunogens. Int. J. Pept. Protein Res. 30 794-800.
22. Mattioli, S., Imberti, L., Stellini, R. and Primi, D. (1995) Mimicry of the immunodominant conformation-dependent antigenic site of hepatitis A virus by motifs selected from synthetic peptide libraries. J. Virol. 69, 5294-5299.
23. McConnell, S. J., Kendall, M. L., Reilly, T. M. and Hoess, R. H. (1994) Constrained peptide libraries as a tool for finding mimotopes. Gene. 151, 115-118.
24. Micheel, B. and Scharte, G. (1993) Multiple antigen injections decrease the yield of hybridomas producing monoclonal antibodies. Hybridoma 12 227-229.
25. Micheel, B., Jantscheff, P., Böttger, V., Scharte, G., Kaiser, G., Stolley, P. and Karawajew, L. (1988) The production and radioimmunoassay application of monoclonal antibodies to fluorescein isothiocyanate (FITC). J. Immunol. Meth. 111, 89-94.
26. Micheel, B., Heymann, S., Scharte, G., Böttger, V., Vogel, F., Döbel, S., Breitling, F., Little, M. and Behrsing, O. (1994) Production of monoclonal antibodies against epitopes of the main coat protein of filamentous fd phages. J. Immunol. Meth. 171, 103-109.
27. Miller, J. L. and Lyle, V. A. (1996) Mimotope/anti-mimotope probing of structural relationships in platelet glycoprotein Ib alpha. Proc. Natl Acad. Sci. USA 93, 3565-3569.
28. Oldenburg, K. R., Loganathan, D., Goldstein, I. J., Schultz, P. G. and Gallop, M. A. (1992) Peptide ligands for a sugar-binding protein isolated from a random peptide library. Proc. Natl Acad. Sci. USA 89, 5393-5397.
29. O'Neil, K. T. and Hoess, R. H. (1995) Phage display: protein engineering by directed evolution. Curr. Opin. Struct. Biol. 5, 443-449.
30. Peters, E. A., Schatz, P. J., Johnson, S. S. and Dower, W. J. (1994) Membrane insertion defects caused by positive charges in the early mature region of protein pIII of filamentous phage fd can be corrected by prIA suppressors. J. Bacteriol. 176, 4296-4305.
31. Roberts, D., Guegler, K. and Winter, J. (1993) Antibody as a surrogate receptor in the screening of a phage display library. Gene128, 67-69.
32. Samuel, D., Patt, R. J. and Abuknesha, R. A. (1988) A sensitive method of detecting proteins on dot and Western blots using a monoclonal antibody to FITC. J. Immunol. Meth. 107, 217-224.
33. Scott, J. K. and Smith, G. P. (1990) Searching for peptide ligands with an epitope library. Science 249, 386-390.
34. Scott, J. K., Loganathan, D., Easley, R. B., Gong, X. and Goldstein, I. J. (1992) A family of concanavalin A-binding peptides from a hexapeptide epitope library. Proc. Natl Acad. Sci. USA 89, 5398-5402.
35. Schmidt, T. G., Koepke, J., Frank, R. and Skerra, A. (1996) Molecular interaction between the Strep-tag affinity peptide and its cognate target, streptavidin. J. Mol. Biol. 255 753-766.
36. Serke, S. and Pachmann, K. (1988) An immunocytochemical method for the detection of fluorochrome-labelled DNA probes hybridized in situ with cellular RNA. J. Immunol. Meth. 112, 207-211.
37. Steward, M. W., Stanley, C. M. and Obeid, O. E. (1995) A mimotope from a solid-phase peptide library induces a measles virus-neutralizing and protective antibody response. J. Virol. 69, 7668-7673.
38. Stoute, J. A., Ballou, W. R., Kolodny, N., Deal, C. D., Wirtz, R. A. and Lindler, L. E. (1995) Induction of humoral immune response against Plasmodium falciparum sporozoites by immunization with a synthetic peptide mimotope whose sequence was derived from screening a filamentous phage epitope library. Infect. Immun. 63, 934-939.
39. Valadon, P., Nussbaum, G., Boyd, L. F., Margulies, D. H. and Scharff, M. D. (1996) Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans. J. Mol. Biol. 261, 11-22.
40. Voss, Jr, E. W., Ed.. (1984) Fluorescein Hapten: An Immunologiocal Probe, CRC Press, Boca Raton, FL.
41. Zhang, H., Zhong, Z. and Pirofski, L. A. (1997) Peptide epitopes recognized by a human anti-cryptococcal glucuronoxylomannan antibody. Infect. Immun. 65, 1158-1164.