Endogenous vasopressin increases acute endotoxin shock-provoked gastrointestinal mucosal injury in the rat

European Journal of Pharmacology

Volumn 352, Issue 2-3, 1998, Pages 257-261

  Varga, Csaba ^a   Pávó, Imre ^b   Lamarque, Dominique ^c   Szepes, Zoltán ^b   Kiss, József ^b   Karácsony, Gizella ^b   László, Ferenc A ^a   László, Ferenc ^b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c HENRI MONDOR HOSPITAL   (France)

Author keywords

Endotoxin shock; Gastrointestinal mucosa; Microcirculation; Vasopressin

Indexed keywords

ENDOTOXIN; VASOPRESSIN; VASOPRESSIN DERIVATIVE; VASOPRESSIN RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; DIGESTIVE SYSTEM INJURY; FEMALE; GASTROINTESTINAL MUCOSA; INTRAVENOUS DRUG ADMINISTRATION; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; VASOPRESSIN BLOOD LEVEL; VASOPRESSIN RELEASE;

ANIMALS; ENDOTOXINS; FEMALE; GASTRIC MUCOSA; INTESTINAL MUCOSA; RATS; RATS, BRATTLEBORO; RATS, WISTAR; SHOCK, SEPTIC; SPECIES SPECIFICITY; VASOPRESSINS;

EID: 0345563238     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00345-8     Document Type: Article

References (26)

1. Baker, C.H., Sutton, E.T., Zhou, Z., Deitz, J.R.M., 1990. Microvascular vasopressin effects during endotoxin shock in the rat. Circ. Shock 30, 81-95.
2. Ben-Manachem, T., Fogel, R., Patel, R.V., 1994. Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit. Ann. Intern. Med. 121, 568-575.
3. Bone, R.C., 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115, 457-469.
4. 2 biosynthesis in endotoxin-induced intestinal damage in the rat. Prostaglandins 38, 319-333.
5. Burnstock, G., 1990. Local mechanisms of blood flow control by perivascular nerves and endothelium. J. Hypertens. 8, S95-S106, Suppl. 7.
6. Dennhardt, R., Gramm, H.J., Meinhold, K., Voigt, K., 1989. Patterns of endocrine secretion during sepsis. Prog. Clin. Biol. Res. 308, 751-760.
7. Filep, J., Rosenkrantz, B., 1987. Mechanism of vasopressin-induced platelet aggregation. Thromb. Res. 45, 7-15.
8. Harlan, J.M., Harker, L.A., Reidy, M.A., Gajdusek, C.M., Schwartz, S.M., Striker, G.E., 1983. Lipopolysaccharide-mediated bovine endothelial cell injury in vitro. Lab. Invest. 48, 269-274.
9. Hutcheson, I.R., Whittle, B.J.R., Boughton-Smith, N.K., 1990. Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat. Br. J. Pharmacol. 101, 815-820.
10. László, F., Whittle, B.J.R., 1994. Constitutive nitric oxide modulates the injurious actions of vasopressin on rat intestinal microcirculation in acute endotoxaemia. Eur. J. Pharmacol. 260, 265-268.
11. László, F., Karácsony, G., Szabó, E., Láng, J., Baláspiri, L., László, F.A., 1991 a. The role of vasopressin in the pathogenesis of ethanol-induced gastric hemorrhagic erosions in rats. Gastroenterology 101, 1242-1248.
12. László, F.A., László, F., de Wied, D., 1991b. Pharmacology and clinical perspectives of vasopressin antagonists. Pharmacol. Rev. 43A, 73-108.
13. László, F., Varga, C., Karácsony, G., Whittle, B.J.R., László, F.A., 1993. Involvement of endogenous vasopressin in endotoxin-induced acute gastrointestinal injury in the rat. Gut 34, S61.
14. László, F., Karácsony, G., Pávó, I., Varga, C., Rojik, I., László, F.A., 1994. Aggressive role of vasopressin in development of different gastric lesions in rats. Eur. J. Pharmacol. 258, 15-22.
15. László, F., Szepes, Z., Karácsony, G., Varga, C., László, F.A., 1996. Endogenous vasopressin damages duodenal mucosa during haemorrhagic shock in rats. Inflammopharmacololgy 4, 379-385.
16. Lefer, A.M., Lefer, D.J., 1993. Pharmacology of the endothelium in ischaemia-reperfusion and circulatory shock. Annu. Rev. Pharmacol. Toxicol. 33, 71-90.
17. Matsuoka, T., Wisner, D.H., 1997. Hemodynamic and metabolic effects of vasopressin blockade in endotoxin shock. Surgery 121, 162-173.
18. Meyrick, B.O., Ryan, U.S., Brigham, K.L., 1986. Direct effects of E. coli endotoxin on structure and permeability of pulmonary endothelial monolayers and the endothelial layer of intimal explants. Am. J. Pathol. 122, 140-151.
19. Nádasy, G.L., Székács, B., Juhász, I., Monos, E., 1992. Pharmacological modulation of prostacyclin and thromboxane production of rat and cat venous tissue slices. Prostaglandins 44, 339-355.
20. Parillo, J.E., 1990. Septic shock in humans: advances in the understand-ing of pathogenesis, cardiovascular dysfunction and therapy. Ann. Intern. Med. 113, 227-242.
21. Reichlin, S., 1985. Neuroendocrinology. In William's Textbook of Endocrinology. Saunders, Philadelphia, pp. 492-511.
22. Robert, A., Kauffman, G.L., 1989. Stress ulcers, erosions, and gastric mucosal injury. In: Gastrointestinal Disease, Pathophysiology, Diagnosis, Management. Saunders, Philadelphia, pp. 772-792.
23. Robertson, G.L., 1987. Posterior pituitary. In: Baxter's Endocrinology and Metabolism. McGraw-Hill, New York, pp. 335-356.
24. Root, R.K., Jacobs, R., 1991. Septicemia and septic shock. Harrison's Principles of Internal Medicine. McGraw Hill, New York, pp. 507-516.
25. Sokol, H.W., Valtin, H., 1982. The Brattleboro rat. Ann. New York Acad. Sci. 394, 1-828.
26. Vanner, S., Jiang, M.-M., Brooks, V.L., Surprenant, A., 1990. Characterization of vasopressin actions in isolated submucosal arterioles of the intestinal microcirculation. Cire. Res. 67, 1017-1026.