Influence of sexual hormone antagonists on the anticonvulsant action of conventional antiepileptic drugs against electrically- and pentylenetetrazol- induced seizures in mice

European Neuropsychopharmacology

Volumn 14, Issue 1, 2004, Pages 77-85

  Borowicz, Kinga K ^a   Łuszczki, Jarogniew ^a   Świa̧der, Mariusz ^a   Kleinrok, Zdzisław ^a   Czuczwar, Stanisław J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

Antiepileptic drugs; Cyproterone; Electroshock maximal; Mifepristone; Pentylenetetrazol evoked seizure; Tamoxifen

Indexed keywords

AMINOPHYLLINE; ANTIANDROGEN; ANTICONVULSIVE AGENT; ANTIESTROGEN; ANTIGESTAGEN; BICUCULLINE; CARBAMAZEPINE; CLONAZEPAM; CYPROTERONE ACETATE; ESTRADIOL; ETHOSUXIMIDE; HORMONE ANTAGONIST; KAINIC ACID; MIFEPRISTONE; N METHYL DEXTRO ASPARTIC ACID; PENTETRAZOLE; PHENOBARBITAL; PHENYTOIN; PROGESTERONE; SEX HORMONE; SEX HORMONE ANTAGONIST; STRYCHNINE; TAMOXIFEN; TESTOSTERONE; VALPROIC ACID;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG COMBINATION; DRUG POTENTIATION; ELECTRIC SHOCK; ELECTROSTIMULATION; FEMALE; IATROGENIC DISEASE; LONG TERM MEMORY; LOW DRUG DOSE; MALE; MEMORY DISORDER; METABOLISM; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SEIZURE THRESHOLD; SEX DIFFERENCE;

EID: 0345549393     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-977X(03)00067-1     Document Type: Article

References (32)

1. Backstrom T. Epileptic seizures in woman related to plasma estrogen and progesterone during the menstrual cycle. Acta Neurol. Scand. 54:1976;321-347.
2. Backstrom B., Zetterlund B., Blom S., Romano M. Effects of intravenous progesterone infusions on the epileptic discharge frequency in women with partial epilepsy. Acta Neurol. Scand. 60:1984;240-248.
3. Borowicz K.K., Luszczki J., Matuszek M., Kleinrok Z., Czuczwar S.J. Effects of tamoxifen, mifepristone, and cyproterone on the electroconvulsive threshold and pentetrazole-induced convulsions in mice. Pol. J. Pharmacol. 54:2002;103-109.
4. Butterbaugh G.C. Postictal events in amygdala-kindled female rats with and without estradiol replacement. Exp. Neurol. 95:1987;697-713.
5. Dunham N.W., Miya T.S. A note on a simple approach for determining neurological deficits in rats and mice. J. Am. Pharmacol. Assoc. 46:1957;208-210.
6. Edwards H.E., Burnham W.M., MacLusky N.J. Testosterone and its metabolites affect afterdischarge thresholds and the development of amygdala kindled seizures. Brain Res. 838:1999;151-157.
7. Frye C.A., Bayon L.E. Cyclic withdrawal from endogenous and exogenous progesterone increases kainic acid and perforant pathway induced seizures. Pharmacol. Biochem. Behav. 62:1999;315-321.
8. Frye C.A., Reed T.A. Androgenic neurosteroids: anti-seizure effects in an animal model of epilepsy. Psychoneuroendocrinology. 23:1998;385-399.
9. Grunewald R.A., Aliberti V., Panayiotopoulos C.P. Exacerbation of typical absence seizures by progesterone. Seizure. 1:1992;137-138.
10. Holmes G.L., Weber D.A. The effects of progesterone on kindling: a developmental study. Dev. Brain Res. 16:1984;45-53.
11. Hom A.C., Butterbaugh G.C. Estrogen alters the acquisition of seizures kindled by repeated amygdala stimulation or pentylenetetrazol administration in ovariectomized female rats. Epilepsia. 27:1986;103-108.
12. Hough C.J., Irwin R.P., Gao X.M., Rogawski M.A., Chuang D.M. Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells. J. Pharmacol. Exp. Ther. 276:1996;143-149.
13. Julien R.M., Fowler G.W., Danielson M.G. The effects of antiepileptic drugs on estrogen-induced electrographic spike wave discharges. J. Pharmacol. 193:1975;647-656.
14. Kokate T.G., Banks M.K., Magee T., Yamaguchi S., Rogawski M.A. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. J. Pharmacol. Exp. Ther. 288:1999;679-684.
15. Lampe H., Bigalke H. Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons. Neuroreport. 1:1990;8-12.
16. Litchfield J.T., Wilcoxon F. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96:1949;99-113.
17. Macdonald R.L., McLean M.J. Anticonvulsant drugs: mechanisms of action. Adv. Neurol. 44:1986;713-736.
18. Marangos P.J., Weiss S.R.B., Montgomery P., Patel J., Narang P.K., Cappabianca A.M., Post R.M. Chronic carbamazepine treatment increases brain adenosine receptors. Epilepsia. 26:1985;493-498.
19. Marcus E.M., Watson W., Goldman P.L. Effects of steroids on cerebral electrical activity. Acta Neurol. 15:1966;521-532.
20. Mattson R.H., Cramer J.A. Epilepsy, sex hormones and antiepileptic drugs. Epilepsia. 26:1985;S40-S51.
21. Moran M.H., Smith S.S. Progesterone withdrawal I: pro-convulsant effects. Brain Res. 807:1998;84-90.
22. Olpe H.R., Baudry M., Jones R.S.G. Electrophysiological and neurochemical investigations on the action of carbamazepine on the rat hippocampus. Eur. J. Pharmacol. 110:1985;71-76.
23. Phillis J.W. Interactions of the anticonvulsants diphenylhydantoin and carbamazepine with adenosine on cerebral cortical neurons. Epilepsia. 25:1984;765-772.
24. Phillis J.W., Wu P.H. The effect of various centrally active drugs on adenosine uptake by the central nervous system. Comp. Biochem. Physiol. 72C:1982;179-187.
25. Rastogi S.K., Ticku M.K. Anticonvulsant profile of drugs which facilitate GABAergic transmission on convulsions mediated by a GABAergic mechanism. Neuropharmacolgy. 25:1986;175-185.
26. Rosse R.B., Mastropaolo J., Novitzki M.R., Deutsch S.I. Depot testosterone attenuates the anticonvulsant effect of flurazepam in mice. Psychoneuroendocrinology. 15:1990;83-85.
27. Skerrit J.H., Johnston G.A.R., Chen Chow S. Interaction of the anticonvulsant carbamazepine with adenosine receptors. 2. Pharmacological studies. Epilepsia. 24:1983;643-650.
28. Steppuhn K.G., Turski L. Modulation of the seizure threshold for excitatory amino acids in mice by antiepileptic drugs and chemoconvulsants. J. Pharmacol. Exp. Ther. 265:1993;1063-1068.
29. Venault P., Chapouthier G., De Carvalho L.P., Simiand J., Morre M., Dodd R.H., Rossier J. Benzodiazepines impair and beta-carbolines enhance performance in learning and memory task. Nature. 321:1986;864-866.
30. Wamil A.W., McLean M.J. Phenytoin blocks N-methyl-D-aspartate responses of mouse central neurons. J. Pharmacol. Exp. Ther. 267:1993;218-222.
31. Weir R.L., Padgett W., Daly J.W., Anderson S.M. Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system. Epilepsia. 25:1984;492-498.
32. Zeise M.L., Kasparow S., Zieglgänsberger W. Valproate suppress N-methyl-D-aspartate-evoked, transient depolarization in the rat neocortex in vitro. Brain Res. 544:1991;345-348.