Crystal Structures of Two Complexes of the Rare-Earth-DOTA-Binding Antibody 2D12.5: Ligand Generality from a Chiral System

Journal of the American Chemical Society

Volumn 125, Issue 49, 2003, Pages 15039-15048

  Corneillie, Todd M ^a   Fisher, Andrew J ^a   Meares, Claude F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SALT BRIDGE;

ANTIBODIES; CHELATION; HYDROGEN BONDS; ISOMERS; RARE EARTH ELEMENTS;

CRYSTAL STRUCTURE;

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; CARBENOID; CARBOXYLIC ACID DERIVATIVE; IMMUNOGLOBULIN F(AB) FRAGMENT; LANTHANIDE; LIGAND; MACROCYCLIC COMPOUND; METAL COMPLEX; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2D12.5; UNCLASSIFIED DRUG; YTTRIUM;

ARTICLE; BINDING AFFINITY; CHELATION; CHIRALITY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DEGLYCOSYLATION; ENANTIOMER; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PHASE TRANSITION; STRUCTURE ANALYSIS;

BINDING SITES; CHELATING AGENTS; CRYSTALLOGRAPHY, X-RAY; GADOLINIUM; HETEROCYCLIC COMPOUNDS; HYDROPHOBICITY; IMMUNOGLOBULIN FRAGMENTS; ISOMERISM; MODELS, MOLECULAR; ORGANOMETALLIC COMPOUNDS; YTTRIUM;

EID: 0345529837     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja037236y     Document Type: Article

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