Hepatic apolipoprotein B biogenesis: An update

Trends in Cardiovascular Medicine

Volumn 8, Issue 1, 1998, Pages 8-14

  Sai Ching, Jim Yeung ^a   Chan, Lawrence ^a  

^a EAST TEXAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A;

ATHEROGENESIS; CELL METABOLISM; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; LIPOPROTEIN SYNTHESIS; LIVER CELL CARCINOMA; LIVER METABOLISM; PRIORITY JOURNAL; REVIEW;

EID: 0345516012     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(97)00120-5     Document Type: Review

References (55)

1. Adeli K Regulated intracellular degradation of apolipoprotein B in semipermeable Hep G2 cells. J Biol Chem. 269:1994;9166-9175.
2. Alexander C, Hamilton RL, Havel RJ Subcellular localization of B apoprotein of plasma lipoproteins in rat liver. J Cell Biol. 69:1976;241-263.
3. Avramoglu RK, Cianflone K, Sniderman AD Role of the neutral lipid accessible pool in the regulation of secretion of apoB-100 lipoprotein particles by Hep G2 cells. J Lipid Res. 36:1995;2513-2528.
4. Bonifacino JS Reversal of fortune for nascent proteins. Nature. 384:1996;405-406.
5. Bonnardel JA, Davis RA: 1995. In Hep G2 cells, translocation, not degradation, determines the fate of the de novo synthesized apolipoprotein B. J Biol Chem 270:28,892-28,896.
6. Borchardt RA, Davis RA: 1987. Intrahepatic assembly of very low density lipoproteins: rate of transport out of the endoplasmic reticulum determines rate of secretion. J Biol Chem 262:16,394-16,402.
7. Boren J, Wettesten M, Sjoberg A, et al.: 1990. The assembly and secretion of apoB 100 containing lipoproteins in Hep G2 cells: evidence for different sites for protein synthesis and lipoprotein assembly. J Biol Chem 265:10,556-10,564.
8. Boren J, Graham L, Wettesten M, Scott J, White A, Olofsson SO The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells: ApoB 100 is cotranslationally integrated into lipoproteins. J Biol Chem. 267:1992;9858-9867.
9. Cartwright IJ, Higgins JA Intracellular events in the assembly of very-low-density-lipoprotein lipids with apolipoprotein B in isolated rabbit hepatocytes. Biochem J. 310:1995;897-907.
10. Chan L: 1992. Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins. J Biol Chem 267:25,621-25,624.
11. Chan L, Seeburg PH RNA editing. Sci Am Sci Med. 2:1995;68-77.
12. Chan L, Chang BHJ, Nakamuta M, Li WH, Smith LC Apobec-1 and apolipoprotein B mRNA editing. Biochim Biophys Acta. 1345:1997;11-26.
13. Chen SH, Habib G, Yang CYet al. Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific inframe stop codon. Science. 238:1987;363-366.
14. Chuck SL, Lingappa VR Pause transfer: a topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation. Cell. 68:1992;9-21.
15. Chuck SL, Lingappa VR: 1993. Analysis of a pause transfer sequence from apolipoprotein B. J Biol Chem 268:22,794-22,801.
16. Dashti N, Williams DL, Alaupovic P Effects of oleate and insulin on the production rates and cellular mRNA concentrations of apolipoproteins in Hep G2 cells. J Lipid Res. 30:1989;1365-1373.
17. Davis RA, Thrift RN, Wu CC, Howell KE: 1990. Apolipoprotein B is both integrated into and translocated across the endoplasmic reticulum membrane: evidence for two functionally distinct pools. J Biol Chem 265:10,005-10,011.
18. Dixon JL, Furukawa S, Ginsberg HN Oleate stimulates secretion of apolipoprotein B-containing lipoproteins from Hep G2 cells by inhibiting early intracellular degradation of apolipoprotein B. J Biol Chem. 266:1991;5080-5086.
19. Furukawa S, Sakata N, Ginsberg HN, Dixon JL: 1992. Studies of the sites of intracellular degradation of apolipoprotein B in Hep G2 cells. J Biol Chem 267:22,630-22,638.
20. Hochstrasser M Protein degradation or regulation: Ub the judge. Cell. 84:1996;813-815.
21. Ingram MF, Shelness GS Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane. J Lipid Res. 37:1996;2202-2214.
22. Jentsch S, Schlenker S Selective protein degradation: a journey's end within the proteasome. Cell. 82:1995;881-884.
23. Kempen HJ, Imbach AP, Giller T, Neumann WJ, Hennes U, Nakada N Secretion of apolipoproteins A-I and B by Hep G2 cells: regulation by substrates and metabolic inhibitors. J Lipid Res. 36:1995;1796-1806.
24. Kopito RR ER quality control: the cytoplasmic connection. Cell. 88:1997;427-430.
25. Lang CA, Davis RA Fish oil fatty acids impair VLDL assembly and/or secretion by cultured rat hepatocytes. J Lipid Res. 31:1990;2079-2086.
26. Leiper JM, Harrison GB, Bayliss JD, Scott J, Pease RJ Systematic expression of the complete coding sequence of apoB-100 does not reveal transmembrane determinants. J Lipid Res. 37:1996;2215-2231.
27. Lowe J, Stock D, Jap B, Zwickl P, Baumeister W, Huber Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science. 268:1995;533-539.
28. Martin-Sanz P, Vance JE, Brindley DN Stimulation of apolipoprotein secretion in very-low-density and high-density lipoproteins from cultured rat hepatocytes by dexamethasone. Biochem J. 271:1990;575-583.
29. Ng T, Walter P Protein translocation across the endoplasmic reticulum. Curr Opin Cell Biol. 6:1994;510-516.
30. Ou WJ, Cameron PH, Thomas DY, Bergeron JJ Association of folding intermediates of glycoproteins with calnexin during protein maturation. Nature. 364:1993;771-776.
31. Patel SB, Grundy SM: 1996. Interactions between microsomal triglyceride transfer protein and apolipoprotein B within the endoplasmic reticulum in a heterologous expression system. J Biol Chem 271:18,686-18,694.
32. Pease RJ, Harrison GB, Scott J Cotranslocational insertion of apolipoprotein B into the inner leaflet of the endoplasmic reticulum. Nature. 353:1991;448-450.
33. Powell LM, Wallis SC, Pease RJ, Edwards YH, Knott TJ, Scott J A novel form of tissue-specific RNA processing produces apolipoprotein B-48 in intestine. Cell. 50:1987;831-840.
34. Pullinger CR, North JD, Teng BB, Rifici VA, Ronhild de Brito AE, Scott J The apolipoprotein B gene is constitutively expressed in Hep G2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life. J Lipid Res. 30:1989;1065-1077.
35. Ribeiro A, Mangeney M, Cardot Pet al. Effect of dietary fish oil and corn oil on lipid metabolism and apolipoprotein gene expression by rat liver. Eur J Biochem. 196:1991;499-507.
36. Rock KL, Gramm C, Rothstein Let al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell. 78:1994;761-771.
37. Sakata N, Wu X, Dixon JL, Ginsberg HN: 1993. Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells. J Biol Chem 268:22,967-22,970.
38. Salam WH, Wilcox HG, Heimberg M Effects of oleic acid on the biosynthesis of lipoprotein apoproteins and distribution into the very-low-density lipoprotein by the isolated perfused rat liver. Biochem J. 251:1988;809-816.
39. Sasaki T, Kishi M, Saito Met al. Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins. J Enzym Inhib. 3:1990;195-201.
40. Sato R, Imanaka T, Takatsuki A, Takano T: 1990. Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment. J Biol Chem 265:11,880-11,884.
41. Schaefer EJ, Lamon-Fava S, Cohn SDet al. Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study. J Lipid Res. 35:1994;779-792.
42. Sharrett AR, Patsch W, Sorlie PD, Heiss G, Bond MG, Davis CE Associations of lipoprotein cholesterols, apolipoproteins A-I and B, and triglycerides with carotid atherosclerosis and coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb. 14:1994;1098-1104.
43. Sparks JD, Sparks CE Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes. J Biol Chem. 265:1990;8854-8862.
44. Tanaka M, Jingami H, Otani H, et al.: 1993. Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes. J Biol Chem 268:12,713-12,718.
45. Thrift RN, Drisko J, Dueland S, Trawick JD, Davis RA Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in a nonhepatic cell line. Proc Natl Acad Sci USA. 89:1992;9161-9165.
46. Wang CN, McLeod RS, Yao Z, Brindley DN Effects of dexamethasone on the synthesis, degradation, and secretion of apolipoprotein B in cultured rat hepatocytes. Arterioscler Thromb Vasc Biol. 15:1995;1481-1491.
47. Wang H, Chen X, Fisher EA N-3 fatty acids stimulate intracellular degradation of apoprotein B in rat hepatocytes. J Clin Invest. 91:1993;1380-1389.
48. Wang S, McLeod RS, Gordon DA, Yao Z: 1996. The microsomal triglyceride transfer protein facilitates assembly and secretion of apolipoprotein B-containing lipoproteins and decreases cotranslational degradation of apolipoprotein B in transfected COS-7 cells. J Biol Chem 271:14,124-14,133.
49. Watts GF, Naoumova R, Cummings MHet al. Direct correlation between cholesterol synthesis and hepatic secretion of apolipoprotein B-100 in normolipidemic subjects. Metab Clin Exp. 44:1995;1052-1057.
50. Wiertz EJ, Tortorella D, Bogyo Met al. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature. 384:1996;432-438.
51. Wu X, Sakata N, Dixon J, Ginsberg HN Exogenous VLDL stimulates apolipoprotein B secretion from Hep G2 cells by both pre- and post-translational mechanisms. J Lipid Res. 35:1994;1200-1210.
52. Wu X, Sakata N, Lui E, Ginsberg HN: 1994b. Evidence for a lack of regulation of the assembly and secretion of apolipoprotein B-containing lipoprotein from Hep G2 cells by cholesteryl ester. J Biol Chem 269:12,375-12,382.
53. Wu X, Zhou M, Huang LS, Wetterau J, Ginsberg HN: 1996. Demonstration of a physical interaction between microsomal triglyceride transfer protein and apolipoprotein B during the assembly of ApoB-containing lipoproteins. J Biol Chem 271: 10,277-10,281.
54. Yeung SJ, Chen SH, Chan L: 1996. Ubiquitin-proteasome pathway mediates intracellular degradation of apolipoprotein B. Biochemistry 35:13,843-13,848.
55. Zhou M, Wu X, Huang LS, Ginsberg HN: 1995. Apoprotein B100, an inefficiently translocated secretory protein, is bound to the cytosolic chaperone, heat shock protein 70. J Biol Chem 270:25,220-25,224.