Dual control by regulators, GntH and GntR, of the GntII genes for gluconate metabolism in Escherichia coli

Journal of Molecular Microbiology and Biotechnology

Volumn 6, Issue 1, 2003, Pages 41-56

  Tsunedomi, Ryouichi ^a   Izu, Hanae ^a   Kawai, Takuya ^a   Yamada, Mamoru ^a  

^a YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

Divergent promoter; Expressional regulation; Gluconate metabolism; gntH; GntII; gntR

Indexed keywords

GLUCONIC ACID; LACTOSE;

ARTICLE; BACTERIAL METABOLISM; CATABOLISM; CELL GROWTH; CONTROLLED STUDY; ESCHERICHIA COLI; GENE CONTROL; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE MUTATION; LACTOSE OPERON; NONHUMAN; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; ARTIFICIAL GENE FUSION; BASE SEQUENCE; DNA, BACTERIAL; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GLUCONATES; LAC OPERON; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPERATOR REGIONS (GENETICS); PLASMIDS; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

ESCHERICHIA COLI;

EID: 0345491593     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: 10.1159/000073407     Document Type: Article

References (33)

1. Aiba, H., Adhya, S., and de Crombrugghe, B. 1981. Evidence for two functional gal promoters in intact Escherichia coli cells. J. Biol. Chem. 256: 11905-11910.
2. Bächi, B., and Kornberg, H.L. 1975. Genes involved in the uptake and catabolism of gluconate by Escherichia coli. J. Gen. Microbiol. 90: 321-335.
3. Bausch, C., Peekhaus, N., Utz, C., Blais, T., Murray, E., Lowary, T., and Conway, T. 1998. Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli. J. Bacteriol. 180:3704-3710.
4. Chang, A.C., and Cohen, S.N. 1978. Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid. J. Bacteriol. 134:1141-1156.
5. Faik, P., and Kornberg, H.L. 1973. Isolation and properties of E. coli mutants affected in gluconate uptake. FEBS Lett. 32:260-264.
6. Hashimoto-Gotoh, T., Yasojima, K., and Tsujimura, A. 1995. Plasmids with kanamycin-resistance gene for site-directed mutagenesis using the oligodeoxyribonucleotide-directed dual amber method. Gene 167:333-334.
7. Istúriz, T., Palmero, E., and Vitelli-Flores, J. 1986. Mutations affecting gluconate catabolism in Escherichia coli. Genetic mapping of the locus for the thermosensitive gluconokinase. J. Gen. Microbiol. 132:3209-3219.
8. Izu, H., Adachi, O., and Yamada, M. 1997a. Gene organization and transcriptional regulation of the gntRKU operon involved in gluconate uptake and catabolism of Escherichia coli. J. Mol. Biol. 267:778-793.
9. Izu, H., Kawai, T., Yamada, Y., Aoshima, H., Adachi, O., and Yamada, M. 1997b. Characterization of the gntT gene encoding a high-affinity gluconate permease in Escherichia coli. Gene 199:203-210.
10. Izu, H., Ito, S., Elias, M.D., and Yamada, M. 2002. Differential control by IHF and cAMP of two oppositely oriented genes, hpt and gcd, in Escherichia coli: Significance of their partially overlapping regulatory elements. Mol. Genet. Genomics 266:865-872.
11. Klemm, P., Tong, S., Nielsen, H., and Conway, T. 1996. The gntP gene of Escherichia coli involved in gluconate uptake. J. Bacteriol. 178: 61-67.
12. Lobell, R.B., and Schleif, R.F. 1990. DNA looping and unlooping by AraC protein. Science 250: 528-532.
13. Miller, J.H. 1972. Experiments in Molecular Genetics. Cold Spring Harbor, Cold Spring Harbor Laboratory.
14. Miller, J.H. 1992. A Short Course in Bacterial Genetics: A Laboratory Manual and Handbook for Escherichia coli and Related Bacteria. Cold Spring Harbor, Cold Spring Harbor Laboratory.
15. Nagel de Zwaig, R., Zwaig, N., Istúriz, T., and Sánchez, R.S. 1973. Mutations affecting gluconate metabolism in Escherichia coli. J. Bacteriol. 114:463-468.
16. Nakano, Y., Yoshida, Y., Yamashita, Y., and Koga, T. 1995. Construction of a series of pACYC-derived plasmid vectors. Gene 162: 157-158.
17. E regulon in dead-cell lysis in stationary-phase Escherichia coli. J. Bacteriol. 182:5231-5237.
18. Peekhaus, N., Tong, S., Murray, E., Reizer, J.R., Saier, M., and Conway, T. 1997. Characterization of a novel transporter family that includes multiple Escherichia coli gluconate transporters and their homologues. FEMS Microbiol. Lett. 147:233-238.
19. Peekhaus, N., and Conway, T. 1998. Positive and negative transcriptional regulation of the Escherichia coli gluconate regulon gene gntT by GntR and the cyclic AMP (cAMP)-cAMP receptor protein complex. J. Bacteriol. 180: 1777-1785.
20. Porco, A., Peekhaus, N., Bausch, C., Tong, S., Istúriz, T., and Conway, T. 1997. Molecular genetic characterization of the Escherichia coli gntT gene of GntI, the main system for gluconate metabolism. J. Bacteriol. 179:1584-1590.
21. Ptashne, M., Johnson, A.D., and Pabo, C.O. 1982. A genetic switch in bacterial virus. Sci. Am. 247:128-130.
22. Sambrook, J., Fritsch, E.F., and Maniatis, T. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, Cold Spring Harbor Laboratory.
23. Sanger, F., Nicklen, S., and Coulson, A.R. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
24. Silhavy, T.J., Berman, M.L., and Enquist, L.W. 1984. Experiments with Gene Fusions. Cold Spring Harbor, Cold Spring Harbor Laboratory Press.
25. Simons, R.W., Houman, F., and Kleckner, N. 1987. Improved single and multicopylacbased cloning vectors for protein and operon fusions. Gene 53:85-96.
26. Søgaard-Andersen, L., and Valentin-Hansen, P. 1993. Protein-protein interactions in gene regulation: The cAMP-CRP complex sets the specificity of a second DNA-binding protein, the CytR repressor. Cell 75:557-566.
27. Tong, S., Porco, A., Istúriz, T., and Conway, T. 1996. Cloning and molecular characterization of the Escherichia coli gntR, gntK, and gntU genes of GntI, the main system for gluconate metabolism. J. Bacteriol. 178:3260-3269.
28. Tsunedomi, R., Izu, H., Kawai, T., Matsushita, K., Ferenci, T., and Yamada, M. 2003. The activator of GntII genes for gluconate metabolism, GntH, exerts negative control of GntR-regulated GntI genes in Escherichia coli. J. Bacte-riol. 185:1783-1795.
29. Weickert, M.J., and Adhya, S. 1993a. Control of transcription of Gal repressor and isorepressor genes in Escherichia coli. J. Bacteriol. 175:251-258.
30. Weickert, M.J., and Adhya, S. 1993b. The galactose regulon of Escherichia coli. Mol. Microbiol. 10: 245-251.
31. Yamada, M., Izu., H., Nitta, T., Kurihara, K., and Sakurai, T. 1998. High-temperature, nonradioactive primer extension assay for determination of a transcription-initiation site. Biotechniques 25:72-78.
32. Yamada, M., Kawai, K., and Izu, H. 1996. Analysis of the Escherichia coli gntT and gntU genes and comparison of the products with their homologues. Biosci. Biotechnol. Biochem. 60:1548-1550.
33. Zwaig, N., Nagel de Zwaig, R., Istúriz, T., and Wecksler, M. 1973. Regulatory mutations affecting the gluconate system in Escherichia coli. J. Bacteriol. 114:469-473.