Bone Graft Alternatives for Spinal Fusion

BioDrugs

Volumn 17, Issue 6, 2003, Pages 391-394

  Grauer, Jonathan N ^a   Beiner, John M ^a   Kwon, Brian K ^a   Vaccaro, Alexander R ^a  

^a ROTHMAN INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 9; GROWTH DIFFERENTIATION FACTOR 5; LIM PROTEIN; OSTEOGENIC PROTEIN 1; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT OSTEOGENIC PROTEIN 1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

BONE GRAFT; BONE GROWTH; BONE MARROW; BONE MATRIX; GROWTH STIMULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; REVIEW; SPINE DISEASE; SPINE FUSION;

ANIMALS; BONE MARROW TRANSPLANTATION; BONE MATRIX; BONE MORPHOGENETIC PROTEINS; BONE TRANSPLANTATION; HUMANS; RECOMBINANT PROTEINS; SPINAL FUSION;

EID: 0345490836     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: 10.2165/00063030-200317060-00002     Document Type: Review

References (39)

1. Arrington ED, Smith WJ, Chambers HG, et al. Complications of iliac crest bone graft harvesting. Clin Orthop 1996 Aug; 329: 300-9
2. Banwart JC, Asher MA, Hassanein RS. Iliac crest bone graft harvest donor site morbidity: a statistical evaluation. Spine 1995 May 1; 20 (9): 1055-60
3. Gupta AR, Shah NR, Patel TC, et al. Perioperative long-term complications of iliac crest bone graft harvesting for spinal surgery: a quantitative review of the literature. Int Med J 2001; 8: 163-6
4. Kurz LT, Garfin SR, Booth Jr RE. Harvesting autogenous iliac bone grafts: a review of complications and techniques. Spine 1989 Dec; 14 (12): 1324-31
5. Prolo DJ, Rodrigo JJ. Contemporary bone graft physiology and surgery. Clin Orthop 1985 Nov; 200: 322-42
6. An HS, Lynch K, Toth J. Prospective comparison of autograft vs allograft for adult posterolateral lumbar spine fusion: differences among freeze-dried, frozen, and mixed grafts. J Spinal Disord 1995 Apr; 8 (2): 131-5
7. Jorgenson SS, Lowe TG, France J, et al. A prospective analysis of autograft versus allograft in posterolateral lumbar fusion in the same patient: a minimum 1-year follow-up in 144 patients. Spine 1994 Sep 15; 19 (18): 2048-53
8. Nugent PJ, Dawson EG. Intertransverse process lumbar arthrodesis with allogeneic fresh-frozen bone graft. Clin Orthop 1993 Feb; 287: 107-11
9. West JL, Ogilvie JW, Bradford DS. Pedicle screw plate fixation with allograft bone [abstract]. Orthop Trans 1991; 15: 733
10. Blanco JS, Sears CJ. Allograft bone use during instrumentation and fusion in the treatment of adolescent idiopathic scoliosis. Spine 1997 Jun 15; 22 (12): 1338-42
11. Dodd CA, Fergusson CM, Freedman L, et al. Allograft versus autograft bone in scoliosis surgery. J Bone Joint Surg Br 1988 May; 70 (3): 431-4
12. Jones KC, Andrish J, Kuivila T, et al. Radiographic outcomes using freeze-dried cancellous allograft bone for posterior spinal fusion in pediatric idiopathic scoliosis. J Pediatr Orthop 2002 May-Jun; 22 (3): 285-9
13. Malloy KM, Hilibrand AS. Autograft versus allograft in degenerative cervical disease. Clin Orthop 2002 Jan; 394: 27-38
14. Vaccaro AR, Chiba K, Heller JG, et al. Bone grafting alternatives in spinal surgery. LaGrange (IL): North Am Spine Society, 2002: 1-16
15. Bucholz RW, Carlton A, Holmes RE. Hydroxyapatite and tricalcium phosphate bone graft substitutes. Orthop Clin North Am 1987 Apr; 18 (2): 323-34
16. Frenkel SR, Moskovich R, Spivak J, et al. Demineralized bone matrix: enhancement of spinal fusion. Spine 1993 Sep 15; 18 (12): 1634-9
17. Lovell TP, Dawson EG, Nilsson OS, et al. Augmentation of spinal fusion with bone morphogenetic protein in dogs. Clin Orthop 1989 Jun; 243: 266-74
18. Martin Jr GJ, Boden SD, Titus L, et al. New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis. Spine 1999 Apr 1; 24 (7): 637-45
19. Morone MA, Boden SD. Experimental posterolateral lumbar spinal fusion with a demineralized bone matrix gel. Spine 1998 Jan 15; 23 (2): 159-67
20. An HS, Simpson JM, Glover JM, et al. Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion: a prospective multicenter study. Spine 1995 Oct 15; 20 (20): 2211-6
21. Lee YP, Wang JC, Kamin LEA, et al. The direct comparison of different commercially available demineralized bone matrix substances in an athymic rat model. Seattle (WA): North Am Spine Society, 2001
22. Wang JC, Davies M, Kanim LEA, et al. Prospective comparison of commercially available demineralized bone matrix for spine fusion. New Orleans (LA): North Am Spine Society, 2000
23. Grauer JN, Patel TC, Erulkar JS, et al. Evaluation of OP-1 as a graft substitute for intertransverse process lumbar fusion. Spine 2001; 26: 127-33
24. Patel TC, Erulkar JS, Grauer JN, et al. Osteogenic protein-1 overcomes the inhibitory effect of nicotine on posterolateral lumbar fusion. Spine 2001 Aug 1; 26 (15): 1656-61
25. Cunningham BW, Shimamoto N, Sefter J, et al. Osteointegration of autograft vs osteogenic protein 1. Seattle (WA): North Am Spine Society, 2001
26. Patel TC, McCulloch JA, Vacarro AR, et al. A pilot safety and efficacy study of OP-1 (rhBMP-7) in posterolateral lumbar fusion as a replacement for iliac crest autograft. Seattle (WA): North Am Spine Society, 2001
27. Patel TC, Vaccaro AR, Truumees E, et al. Two-year follow-up of a safety and efficacy study of OP-1 (rhBMP-7) as an adjunct to posterolateral lumbar fusion. Seattle (WA): North Am Spine Society, 2001
28. Speck G. Posterolateral lumbar fusion using OP-1: preliminary results. Adelaide (SA): Australian Spine Society, 2000
29. Schimandle JH, Boden SD, Hutton WC. Experimental spine fusion with recombinant human bone morphogenetic protein 2 (rhBMP-2). Spine 1995 Jun; 20 (12): 1326-37
30. Boden SD, Kang J, Sandhu H, et al. Use of recombinant bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial. 2002 Volvo Award in clinical studies. Spine 2002 Dec 1; 27 (23): 2662-73
31. Sandhu HS, Toth JM, Diwan AD, et al. Histologic evaluation of the efficacy of rhBMP-2 compared with autograft bone in sheep spinal anterior interbody fusion. Spine 2002 Mar 15; 27 (6): 567-75
32. Burkus JK, Heim SE, Gornet MF, et al. Is INFUSE bone graft superior to autograft bone? An integrated analysis of clinical trials using the LT-CAGE lumbar tapered fusion device. J Spinal Disord Tech 2003 Apr; 16 (2): 113-22
33. Burkus JK, Transfeldt EE, Kitchel SH, et al. Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2. Spine 2002 Nov 1; 27 (21): 2396-408
34. Helm GA, Alden TD, Beres EJ, et al. Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent. J Neurosurg 2000; 92 (2 Suppl.): 191-6
35. Spiro RC, Thompson AY, Poser JW. Spinal fusion with recombinant human growth and differentiation factor-5 combined with mineralized collagen matrix. Anat Rec 2001 Aug 1; 263 (4): 388-95
36. Boden SD, Titus L, Hair G, et al. Lumbar spine fusion by local gene therapy with a cDNA encoding a novel osteoinductive protein (LMP-1). Spine 1998 Dec 1; 23 (23): 2486-92
37. Burwell RG. The function of bone marrow in the incorporation of bone graft. Clin Orthop 1985 Nov; 200: 125-41
38. Curylo LJ, Johnstone B, Petersilge CA, et al. Augmentation of spinal arthrodesis with autologous bone marrow in a rabbit posterolateral spine fusion model. Spine 1999 Mar 1; 24 (5): 434-9
39. Muschler GF. Bone marrow aspirate: a source of connective tissue stem cells. Emerging Technologies Conference; 2002 Oct 18; Washington (DC)