Diastereoselective synthesis, binding affinity for vitamin D receptor, and chiral stationary phase chromatography of hydroxy analogs of 1,25- dihydroxycholecalciferol and 25-hydroxycholecalciferol

Chirality

Volumn 11, Issue 9, 1999, Pages 701-706

  Odrzywolska, Malłgorzata ^a   Chodyński, Michalł ^a   Zorgdrager, Jan ^b   Van De Velde, Jan Paul ^b   Kutner, Andrzej ^a  

^a INDUSTRIAL CHEMISTRY RESEARCH INSTITUTE   (Poland)

^b Solvay Pharmaceuticals Inc   (Netherlands)

Author keywords

(24R) 1,24,25 and (24S) 1,24,25 trihydroxycholecalciferols; (24R) 24,25 and (24S),24,25 dihydroxycholecalciferols; Binding affinity for vitamin D receptor; Chiral stationary phase HPLC; Diastereoselective hydroxylation

Indexed keywords

CALCIFEDIOL; CALCITRIOL DERIVATIVE; OXAZIRIDINE DERIVATIVE; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHIRALITY; DIASTEREOISOMER; DRUG HYDROXYLATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SPECTRAL SENSITIVITY; STEREOCHEMISTRY;

ANIMALS; CALCIFEDIOL; CALCITRIOL; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING; RECEPTORS, CALCITRIOL; STEREOISOMERISM;

EID: 0345466618     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(1999)11:9<701::AID-CHIR6>3.0.CO;2-L     Document Type: Article

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