Laryngeal Carcinoma: Multivariate Analysis of Prognostic Factors in 1 252 Consecutive Patients Treated with Primary Radiotherapy

Acta Oncologica

Volumn 42, Issue 7, 2003, Pages 771-778

  Johansen, Lars V ^a   Grau, Cai ^a   Overgaard, Jens ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; HEMOGLOBIN; RADIOTHERAPY; STATISTICAL TESTS; TUMORS;

RECURRENT DISEASES; RESIDUAL TUMOR; SQUAMOUS CELL CARCINOMA (SCC);

ONCOLOGY;

HEMOGLOBIN;

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; HUMAN TISSUE; LARYNX CARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; SEX DIFFERENCE; SQUAMOUS CELL CARCINOMA; STATISTICAL ANALYSIS; SURVIVAL RATE; TISSUE DIFFERENTIATION; TREATMENT FAILURE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; CARCINOMA, SQUAMOUS CELL; FEMALE; HEMOGLOBINS; HUMANS; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM RECURRENCE, LOCAL; PROGNOSIS; RADIOTHERAPY DOSAGE; SEX FACTORS; TREATMENT OUTCOME;

EID: 0345448988     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/02841860310017595     Document Type: Article

References (32)

1. Johansen LV, Grau C, Overgaard J. Supraglottic carcinoma. Patterns of failure and salvage treatment after curatively intended radiotherapy in 410 consecutive patients. Int J Radiat Oncol Biol Phys 2002; 53: 948-58.
2. Johansen LV, Grau C, Overgaard J. Glottic carcinoma - patterns of failure and salvage treatment after curative radiotherapy in 861 consecutive patients. Radiother Oncol 2002; 63: 257-67.
3. Cancer incidence in Denmark 1984. Copenhagen: Danish Cancer Society; 1987.
4. Cancer incidence in Denmark 1998. Copenhagen: The Danish National Board of Health; 2002.
5. Hansen HS. Neoplasma malignum laryngis. Thesis. Copenhagen: Polyteknisk Forlag; 1975.
6. Jorgensen K. Carcinoma laryngis. Thesis. Aarhus University; 1976.
7. Lund C, Sogaard H, Jorgensen K, Elbrond O, Hjelm-Hansen M, Andersen AP. Histological grading of epidermoid carcinomas in the head and neck. Dan Med Bull 1977; 24: 162-6.
8. TNM classification of malignant tumors: third enlarged and revised edition. In: Harmer MH, ed. Geneva: UICC; 1982. p. 27-32.
9. Overgaard J, Hansen HS, Andersen AP, et al. Misonidazole combined with split-course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx: report from the DAHANCA 2 study. Int J Radiat Oncol Biol Phys 1989; 16: 1065-8.
10. Overgaard J, Hansen HS, Overgaard M, et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol 1998; 46: 135-46.
11. Hansen HS, Rygard J, Andersen AP, et al. Bleomycin, methotrexate and vincristine before irradiation of stage III and IV laryngeal and pharyngeal squamous cell carcinoma. A study initiated by the Danish Society of Head and Neck Cancer. Acta Oncol 1987; 26: 13-8.
12. Jorgensen K, Godballe C, Hansen O, Bastholt L. Cancer of the larynx - treatment results after primary radiotherapy with salvage surgery in a series of 1 005 patients. Acta Oncol 2002; 41: 69-76.
13. Carl J, Andersen LJ, Pedersen M, Greisen O. Prognostic factors of local control after radiotherapy in T1 glottic and supraglottic carcinoma of the larynx. Radiother Oncol 1996; 39: 229-33.
14. Kowalski LP, Batista MB, Santos CR, Scopel A, Salvajolli JV, Torloni H. Prognostic factors in T3, N0-1 glottic and transglottic carcinoma. A multifactorial study of 221 cases treated by surgery or radiotherapy. Arch Otolaryngol Head Neck Surg 1996; 122: 77-82.
15. Tarnawski R, Skladowski K, Maciejewski B. Prognostic value of hemoglobin concentration in radiotherapy for cancer of supraglottic larynx. Int J Radiat Oncol Biol Phys 1997; 38: 1007-11.
16. Bentzen SM, Johansen LV, Overgaard J, Thames HD. Clinical radiobiology of squamous cell carcinoma of the oropharynx. Int J Radiat Oncol Biol Phys 1991; 20: 1197-206.
17. Nguyen-Tan PF, Le QT, Quivey JM, Singer M, Terris DJ, Goffinet DR, et al. Treatment results and prognostic factors of advanced T3-4 laryngeal carcinoma: the University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience. Int J Radiat Oncol Biol Phys 2001; 50: 1172-80.
18. MacKenzie R, Franssen E, Balogh J, Birt D, Gilbert R. The prognostic significance of tracheostomy in carcinoma of the larynx treated with radiotherapy and surgery for salvage. Int J Radiat Oncol Biol Phys 1998; 41: 43-51.
19. Marshak G, Brenner B, Shvero J, et al. Prognostic factors for local control of early glottic cancer. The Rabin Medical Center retrospective study on 207 patients. Int J Radiat Oncol Biol Phys 1997; 43: 1009-13.
20. Raitiola H, Pukander J, Laippala P. Glottic and supraglottic laryngeal carcinoma: differences in epidemiology, clinical characteristics and prognosis. Acta Otolaryngol 1999; 119: 847-51.
21. Jakobsen J, Hansen O, Jorgensen KE, Bastholt L. Lymph node metastases from laryngeal and pharyngeal carcinomas - calculation of burden of metastasis and its impact on prognosis. Acta Oncol 1998; 37: 489-93.
22. Bentzen JK, Hansen HS, Nielsen HW. The prognostic importance of volume-weighted mean nuclear volume, mitotic index, and other stereologically measured quantitative parameters in supraglottic laryngeal carcinoma. Cancer 1999; 86: 2222-8.
23. Raitiola H, Pukander J. Symptoms of laryngeal carcinoma and their prognostic significance. Acta Oncol 2000; 39: 213-6.
24. Geelen CP, Hordijk GJ, Ravasz LA, Terhaard CH. Degree of tumour differentiation as a prognostic factor in advanced laryngeal cancer. Acta Otorhinolaryngol Belg 1995; 49: 1-4.
25. Kokoska MS, Piccirillo JF, el Mofty SK, Emami B, Haughey BH, Schoinick SB. Prognostic significance of clinical factors and p53 expression in patients with glottic carcinoma treated with radiation therapy. Cancer 1996; 78: 1693-700.
26. Morales-Angulo C, Val-Bernal F, Buelta L, Fernandez F, Garcia-Castrillo L, Rama J. Prognostic factors in supraglottic laryngeal carcinoma. Otolaryngol Head Neck Surg 1998; 119: 548-53.
27. Yilmaz T, Hosal AS, Gedikoglu G, Kaya S. Prognostic significance of histopathological parameters in cancer of the larynx. Eur Arch Otorhinolaryngol 1999; 256: 139-44.
28. Nathan CA, Sanders K, Abreo FW, Nassar R, Glass J. Correlation of p53 and the proto-oncogene eIF4E in larynx cancers: prognostic implications. Cancer Res 2000; 60: 3599-604.
29. Nicolai P, Redaelli de Zinis LO, Tomenzoli D, et al. Prognostic determinants in supraglottic carcinoma: univariate and Cox regression analysis. Head Neck 1997; 19: 323-34.
30. Raitiola H, Wigren T, Pukander J. Radiotherapy outcome and prognostic factors in early glottic carcinoma. Auris Nasus Larynx 2000; 27: 153-9.
31. Sanderson RJ, de Boer MF, Damhuis RA, Meeuwis CA, Knegt PP. The influence of alcohol and smoking on the incidence of oral and oropharyngeal cancer in women. Clin Otolaryngol 1997; 22: 444-8.
32. Sanderson RJ, Ironside JA. Squamous cell carcinomas of the head and neck. Br Med J 2002; 325(7368): 822-7.