Probing the microenvironment of intracellular bacterial pathogens

Microbes and Infection

Volumn 1, Issue 6, 1999, Pages 445-453

  Harb, Omar S ^a   Abu Kwaik, Yousef ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

DD PCR; In vivo expression technology; Legionella; Phagosome; Salmonella

Indexed keywords

BACTERIAL DNA; BETA GALACTOSIDASE; CHLORAMPHENICOL ACETYLTRANSFERASE; GREEN FLUORESCENT PROTEIN; LUCIFERASE;

BACTERIAL GENE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; COMPUTER ANALYSIS; DNA DETERMINATION; GENE EXPRESSION; HOST PARASITE INTERACTION; LEGIONELLA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW; SALMONELLA;

BACTERIA (MICROORGANISMS); LEGIONELLA; SALMONELLA;

EID: 0345440149     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(99)80048-3     Document Type: Article

References (54)

1. AbuKwaik Y., Gao L.Y., Stone B.J., Venkataraman C., Harb O.S. Invasion of protozoa by Legionella pneumophila and its role in bacterial ecology and pathogenesis. Appl. Environ. Microbiol. 64:1998;3127-3133.
2. AbuKwaik Y. The phagosome containing Legionella pneumophila within the protozoan Hartmannella vermiformis is surrounded by the rough endoplasmic reticulum. Appl. Environ. Microbiol. 62:1996;2022-2028.
3. AbuKwaik Y., Gao L.Y., Stone B.J., Harb O.S. Invasion of mammalian and protozoan cells by Legionella pneumophila. Bull. Inst. Pasteur. 96:1998;237-247.
4. AbuKwaik Y. Fatal attraction of mammalian cells to Legionella pneumophila. Mol. Microbiol. 30:1998;689-696.
5. Clemens D.L., Horwitz M.A. The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin. J. Exp. M. 184:1996;1349-1355.
6. Clemens D.L., Horwitz M.A. Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J. Exp. M. 181:1995;257-270.
7. Sturgill-Koszycki S., Schaible U.E., Russell D.G. Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis. EMBO J. 15:1996;6960-6968.
8. Sturgill-Koszycki S., Schlesinger P.H., Chakraborty P., Haddix P.L., Collins H.L., Fok A.K., Allen R.D., Gluck S.L., Heuser J., Russell D.G. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science. 263:1994;678-681.
9. Bernardini M.L., Mounier J., D Hauteville H., Coquis-Rondon M., Sansonetti P.J. Identification of icsA a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin. Proc. Natl. Acad. Sci. USA. 86:1989;3867-3871.
10. Finlay B.B., Falkow S. Common themes in microbial pathogenicity revisited. Microbiol. Mol. Biol. Rev. 61:1997;136-169.
11. Leimeister-Wachter M., Domann E., Chakraborty T. The expression of virulence genes in Listeria monocytogenes is thermoregulated. J. Bacteriol. 174:1992;947-952.
12. Dellagostin O.A., Esposito G., Eales L.J., Dale J.W., McFadden J. Activity of mycobacterial promoters during intracellular and extracellular growth. Microbiology. 141:1995;1785-1792.
13. Chen C.Y., Eckmann L., Libby S.J., Fang F.C., Okamoto S., Kagnoff M.F., Fierer J., Guiney D.G. Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infect Immun. 64:1996;4739-4743.
14. Garcia-DelPortillo F., Foster J.W., Maguire M.E., Finlay B.B. Characterization of the micro-environment of Salmonella typhimurium- containing vacuoles within MDCK epithelial cells. Mol. Microbiol. 6:1992;3289-3297.
15. GarciaVescovi E., Soncini F.C., Groisman E.A. Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence. Cell. 84:1996;165-174.
16. AbuKwaik Y., Gao L.Y., Harb O.S., Stone B.J. Transcriptional regulation of the macrophage-induced gene (gspA) of Legionella pneumophila and phenotypic characterization of a null mutant. Mol. Microbiol. 24:1997;629-642.
17. AbuKwaik Y. Induced expression of the Legionella pneumophila gene encoding a 20-kilodalton protein during intracellular infection. Infect. Immun. 66:1998;203-212.
18. Mahan M.J., Tobias J.W., Slauch J.M., Hanna P.C., Collier R.J., Mekalanos J.J. Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proc. Natl. Acad. Sci. USA. 92:1995;669-673.
19. Slauch J.M., Mahan M.J., Mekalanos J.J. In vivo expression technology for selection of bacterial genes specifically induced in host tissues. Methods Enzymol. 235:1994;481-492.
20. Mahan M.J., Slauch J.M., Hanna P.C., Camilli A., Tobias J.W., Waldor M.K., Mekalanos J.J. Selection for bacterial genes that are specifically induced in host tissues: the hunt for virulence factors. Infect. Agents Dis. 2:1993;263-268.
21. Heithoff D.M., Conner C.P., Hanna P.C., Julio S.M., Hentschel U., Mahan M.J. Bacterial infection as assessed by in vivo gene expression. Proc. Natl. Acad. Sci. USA. 94:1997;934-939.
22. Pettersson J., Nordfelth R., Dubinina E., Bergman T., Gustafsson M., Magnusson K.E., Wolf-Watz H. Modulation of virulence factor expression by pathogen target cell contact. Science. 273:1996;1231-1233.
23. Contag C.H., Contag P.R., Mullins J.I., Spilman S.D., Stevenson D.K., Benaron D.A. Photonic detection of bacterial pathogens in living hosts. Mol. Microbiol. 18:1995;593-603.
24. Valdivia R.H., Falkow S. Fluorescence-based isolation of bacterial genes expressed within host cells. Science. 277:1997;2007-2011.
25. Valdivia R.H., Falkow S. Probing bacterial gene expression within host cells. Trends Microbiol. 5:1997;360-363.
26. Valdivia R.H., Falkow S. Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol. Microbiol. 22:1996;367-378.
27. Valdivia R.H., Hromockyj A.E., Monack D., Ramakrishnan L., Falkow S. Applications for green fluorescent protein (GFP) in the study of host- pathogen interactions. Gene. 173:1996;47-52.
28. Lee B.Y., Horwitz M.A. Identification of macrophage and stress-induced proteins of Mycobacterium tuberculosis. J. Clin. Invest. 96:1995;245-249.
29. Buchmeier N.A., Heffron F. Induction of Salmonella stress proteins upon infection of macrophages. Science. 248:1990;730-732.
30. Abshire K.Z., Neidhardt F.C. Analysis of proteins synthesized by Salmonella typhimurium during growth within a host macrophage. J. Bacteriol. 175:1993;3734-3743.
31. AbuKwaik Y., Eisenstein B.I., Engleberg N.C. Phenotypic modulation by Legionella pneumophila upon infection of macrophages. Infect. Immun. 61:1993;1320-1329.
32. AbuKwaik Y., Engleberg N.C. Cloning and molecular characterization of a Legionella pneumophila gene induced by intracellular infection and by various in vitro stress conditions. Mol. Microbiol. 13:1994;243-251.
33. Fernandez R.C., Logan S.M., Lee S.H., Hoffman P.S. Elevated levels of Legionella pneumophila stress protein Hsp60 early in infection of human monocytes and L929 cells correlate with virulence. Infect. Immun. 64:1996;1968-1976.
34. Burns-Keliher L.L., Portteus A., Curtiss R. Specific detection of Salmonella typhimunium proteins synthesized intracellularly. J. Bacteriol. 179:1997;3604-3612.
35. Harb O.S., AbuKwaik Y. Identification of the aspartate-β-semialdehyde dehydrogenase gene of Legionella pneumophila and characterization of a null mutant. Infect. Immun. 66:1998;1898-1903.
36. Suk K., Das S., Sun W., Jwang B., Barthold S.W., Flavell R.A., Fikrig E. Borrelia burgdorferi genes selectively expressed in the infected host. Proc. Natl. Acad. Sci. USA. 92:1995;4269-4273.
37. Susa M., Hacker J., Marre R. De novo synthesis of Legionella pneumophila antigens during intracellular growth in phagocytic cells. Infect. Immun. 64:1996;1679-1684.
38. Kinger A.K., Tyagi J.S. Identification and cloning of genes differentially expressed in the virulent strain of Mycobacterium tuberculosis. Gene. 131:1993;113-117.
39. Straus D., Ausubel F.M. Genomic subtraction for cloning DNA corresponding to deletion mutations. Proc. Natl. Acad. Sci. USA. 87:1990;1889-1893.
40. Lisitsyn N., Wigler M. Cloning the differences between two complex genomes. Science. 259:1993;946-951.
41. Timblin C., Battey J., Kuehl W.M. Application for PCR technology to subtractive cDNA cloning: identification of genes expressed specifically in murine plasmacytoma cells. Nucleic Acids Res. 18:1990;1587-1593.
42. Quinn F.D., Newman G.W., King C.H. In search of virulence factors of human bacterial disease. Trends Microbiol. 5:1997;20-26.
43. Kikuta-Oshima L.C., King C.H., Shinnick T.M., Quinn F.D. Methods for the identification of virulence genes expressed in Mycobacterium tuberculosis strain H37Rv. Ann. NY Acad. Sci. 730:1994;263-265.
44. Plum G., Clark-Curtiss J.E. Induction of Mycobacterium avium gene expression following phagocytosis by human macrophages. Infect. Immun. 62:1994;476-483.
45. Plum G., Brenden M., Clark-Curtiss J.E., Pulverer G. Cloning sequencing and expression of the mig gene of Mycobacterium avium which codes for a secreted macrophage-induced protein. Infect. Immun. 65:1997;4548-4557.
46. Meyer M., VvonGrunberg P.W., Knoop T., Hartmann P., Plum G. The macrophage-induced gene mig as a marker for clinical pathogenicity and in vitro virulence of Mycobacterium avium complex strains. Infect. Immun. 66:1998;4549-4552.
47. Liang P., Pardee A.B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257:1992;967-971.
48. AbuKwaik Y., Pederson L.L. The use of differential display-PCR to isolate and characterize a Legionella pneumophila locus induced during the intracellular infection of macrophages. Mol. Microbiol. 21:1996;543-556.
49. Service R.F. DNA chips survey an entire genome. Science. 281:1998;1122.
50. Service R.F. Microship arrays put DNA on the spot. Science. 282:1998;400-596.
51. Groisman E.A., Ochman H. Pathogenicity islands: bacterial evolution in quantum leaps. Cell. 87:1996;791-794.
52. Hacker J., Blum-Oehler G., Muhldorfer I., Tschape H. Pathogenicity islands of virulent bacteria: structure function and impact on microbial evolution. Mol. Microbiol. 23:1997;1089-1097.
53. Frosch M., Reidl J., Vogel U. Genomics in infectious diseases: approaching the pathogens. Trends Microbiol. 6:1998;346-349.
54. Byrne B., Swanson M.S. Expression of Legionella pneumophila virulence traits in response to growth conditions. Infect. Immun. 66:1998;3029-3034.