Influence of salt and pH on the hydrophobicity parameters of antisense nucleosides studied by reversed-phase thin-layer chromatography and multivariate mathematical-statistical methods

Journal of Biochemical and Biophysical Methods

Volumn 41, Issue 1, 1999, Pages 21-30

  Cserháti, Tibor ^a   Forgács, Esther ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

Antisense nucleosides; Lipophilicity; Spectral mapping

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ANTIVIRUS AGENT;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; HYDROPHOBICITY; METHODOLOGY; MULTIVARIATE ANALYSIS; NONHUMAN; PH; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; SPECTROSCOPY;

CHROMATOGRAPHY, THIN LAYER; DEOXYADENOSINES; DEOXYURIDINE; DNA, ANTISENSE; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; MULTIVARIATE ANALYSIS; OLIGONUCLEOTIDES, ANTISENSE; SALTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0345426354     PISSN: 0165022X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-022X(99)00029-9     Document Type: Article

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