Theoretical analysis of the thermal effects during in vivo tissue electroporation

Bioelectrochemistry

Volumn 61, Issue 1-2, 2003, Pages 99-107

  Davalos, Rafael V ^a   Rubinsky, Boris ^a   Mir, Lluis M ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CNRS   (France)

Author keywords

Bioheat equation; Electrochemotherapy; Electrogenetherapy; Electropermeabilization; Joule heating; Thermal effects

Indexed keywords

BLOOD; CELL MEMBRANES; DRUG PRODUCTS; ELECTRIC CURRENTS; ELECTRODES; HEAT LOSSES; MACROMOLECULES; MAGNETIC PERMEABILITY; METABOLISM; MOLECULES; THERMAL EFFECTS;

ELECTROPORTATION; PULSE FREQUENCY;

TISSUE;

ARTICLE; ELECTRODE; ELECTROPORATION; FINITE ELEMENT ANALYSIS; GEOMETRY; HEAT TREATMENT; THERMAL EXPOSURE; TISSUE BLOOD FLOW; TISSUE DISTRIBUTION;

EID: 0345415157     PISSN: 15675394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bioelechem.2003.07.001     Document Type: Article

References (24)

1. Mir L.M. Therapeutic perspectives of in vivo cell electropermeabilization. Bioelectrochemistry. 53:2001;1-10.
2. Weaver J.C. Electroporation of cells and tissues. IEEE Transactions on Plasma Science. 28:2000;24-33.
3. Somiari S., Glasspool-Malone J., Drabick J.J., Gilbert R.A., Heller R., Jaroszeski M.J., Malone R.W. Theory and in vivo application of electroporative gene delivery. Molecular Therapy. 2:2000;178-187.
4. Mir L.M., Glass L.F., Sersa G., Teissie J., Domenge C., Miklavčič D., Jaroszeski M.J., Orlowski S., Reintgen D.S., Rudolf Z., Belehradek M., Gilbert R., Rols M.P., Belehradek J., Bachaud J.M., Deconti R., Stabuc B., Cemazar M., Coninx P., Heller R. Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy. British Journal of Cancer. 77:1998;2336-2342.
5. Miklavčič D., Semrov D., Mekid H., Mir L.M. A validated model of in vivo electric field distribution in tissues for electrochemotherapy and for DNA electrotransfer for gene therapy. Biochimica et Biophysica Acta. 1523:2000;73-83.
6. Henriques F.C., Moritz A.R. Studies in thermal injuries: the predictability and the significance of thermally induced rate processes leading to irreversible epidermal damage. Archives of Pathology. 43:1947;489-502.
7. Diller K.R. Choi Y.I. Bioengineering Heat Transfer. Advances in Heat Transfer. vol. 32:1992;157-357 Academic Press, Boston.
8. Lee R.C., Zhang D., Hannig J. Yarmish M.L., Diller K.R., Toner M. Ann. Rev. Biomed. Eng. vol. 2:2000;477-509 Annual Review Press, Palo Alto.
9. Pliquett U., Gift E.A., Weaver J.C. Determination of the electric field and anomalous heating caused by exponential pulses with aluminum electrodes in electroporation experiments. Bioelectrochemistry and Bioenergetics. 39:1996;39-53.
10. Gallo S.A., Sen A., Hensen M.L., Hui S.W. Temperature-dependent electrical and ultrastructural characterizations of porcine skin upon electroporation. Biophysical Journal. 82:2002;109-119.
11. Kotnik T., Miklavčič D. Theoretical evaluation of the distributed power dissipation in biological cells exposed to electric field. Bioelectromagnetics. 21:2000;385-394.
12. Carney C.K. Choi Y.I. Bioengineering Heat Transfer. Advances in Heat Transfer. vol. 28:1992;19-122 Academic Press, Boston.
13. Eto T.K., Rubinsky B. Berger S.A., Goldsmith W., Lewis E.R. Introduction to Bioengineering. 1996;Oxford Univ. Press, Oxford.
14. Davalos R.V., Rubinsky B., Otten D.M. A feasibility study for electrical impedance tomography as a means to monitor tissue electroporation for molecular medicine. IEEE Transactions on Biomedical Engineering. 49:2002;400-403.
15. Pennes H.H. Analysis of tissue and arterial blood temperatures in the resting forearm. Journal of Applied Physiology. 1:1948;93-122.
16. Suzuki T., Shin B., Fujikura K., Matsuzaki T., Takata K. Direct gene transfer into rat liver cells by in vivo electroporation. FEBS Letters. 425:1998;436-440.
17. Duck F.A. Physical Properties of Tissues: A Comprehensive Reference Book. 1990;Academic Press, San Diego.
18. Boone K., Barber D., Brown B. Review-imaging with electricity: report of the European concerted action on impedance tomography. Journal of Medical Engineering and Technology. 21:1997;201-232.
19. Incropera F.P., De Witt D.P. Fundumentals of Heat and Mass Transfer. 2002;Wiley, New York.
20. Mir L.M. Therapeutic perspectives of in vivo cell electropermeabilization. Bioelectrochemistry. 53:2001;1-10.
21. Deng Z.S., Liu J. Blood perfusion-based model for characterizing the temperature fluctuations in living tissue. Physica. A, Statistical Mechanics and its Applications. 300:2001;521-530.
22. Gehl J., Skovsgaard T., Mir L.M. Vascular reactions to in vivo electroporation: characterization and consequences for drug and gene delivery. Biochimica et Biophysica Acta. 1569:2002;51-58.
23. Martin G.T., Pliquett U.F., Weaver J.C. Theoretical analysis of localized heating in human skin subjected to high voltage pulses. Bioelectrochemistry. 57:2002;55-64.
24. Pliquett U.F., Martin G.T., Weaver J.C. Kinetics of the temperature rise with human stratum corneum during electroporation and pulsed high-voltage iontophoresis. Bioelectrochemistry. 57:2002;65-72.