IL-4 induces eotaxin in human dermal fibroblasts

International Archives of Allergy and Immunology

Volumn 120, Issue SUPPL. 1, 1999, Pages 19-23

  Mochizuki, Mitsuru ^a   Schröder, Jens M ^b   Christophers, Enno ^b   Yamamoto, Shoso ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

Chemokine; Eosinophil; Eotaxin; Fibroblast; IL 4

Indexed keywords

CYTOKINE; EOTAXIN; INTERLEUKIN 4; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

CELL INFILTRATION; CONFERENCE PAPER; DERMIS; EOSINOPHIL; FIBROBLAST; GLYCOSYLATION; HELPER CELL; HUMAN; HUMAN CELL; MAST CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN DISEASE; SKIN MANIFESTATION; SUPERNATANT;

CHEMOKINES, CC; CHEMOTACTIC FACTORS, EOSINOPHIL; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; FIBROBLASTS; HUMANS; INTERLEUKIN-4; SKIN; TH2 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0345410963     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053587     Document Type: Conference Paper

References (21)

1. Gaga M, Frew AJ, Varney VA, Kay AB: Eosinophil activation and T lymphocyte infiltration in allergen-induced late phase skin reactions and classical delayed-type hypersensitivity. J Immunol 1991;147:816-822.
2. Leiferman KM: A current perspective on the role of eosinophils in dermatologic diseases. J Am Acad Dermatol 1991;24:1101-1112.
3. Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, Corrigan C, Durham SR, Kay AB: Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
4. Vowels BR, Rook AH, Cassin M, Zweiman B: Expression of interleukin-4 and interleukin-5 mRNA in developing cutaneous late-phase reactions. J Allergy Clin Immunol 1995;96:92-96.
5. Heath H, Qin S, Rao P, Wu L, LaRosa G, Kassam N, Ponath PD, Mackay CR: Chemokine receptor usage by human eosinophils. J Clin Invest 1997;99:178-184.
6. Mochizuki M, Bartels J, Mallet AI, Christophers E, Schröder JM: IL-4 induces eotaxin: A possible mechanism of selective eosinophil recruitment in helminth infection and atopy. J Immunol 1998;160:60-68.
7. Sticherling M, Kupper M, Koltrowiz F, Bronscheuer E, Kulke R, Klinger M, Kameyoshi Y, Christophers E, Schröder M: Detection of the chemokine RANTES in cytokine-stimulated human dermal fibroblasts. J Invest Dermatol 1995;105:585-591.
8. Bartels J, Sculter C, Richter E, Noso N, Kulke R, Christophers E, Schröder M: Human dermal fibroblasts express eotaxin: Molecular cloning, mRNA expression, and identification of eotaxin sequence variants. Biochem Biophys Commun 1996;225:1045-1051.
9. Petering H, Hochstetter R, Kimming D, Smolarski R, Kapp A, Elsner J: Detection of MCP-4 in dermal fibroblasts and its activation of the respiratory burst in human eosinophils. J Immunol 1998;160:555-558.
10. Noso N, Sticherling M, Bartels J, Mallet AI, Christophers E, Schröder M: Identification of an N-terminally truncated form of the chemokine RANTES and granulocyte-macrophage colony-stimulating factor as major eosinophil attractants released by cytokine-stimulated dermal fibroblasts. J Immunol 1996;156:1946-1953.
11. Noso N, Bartels J, Mallet AI, Mochizuki M, Christophers E, Schröder JM: Delayed production of biologically active O-glycosylated forms of human eotaxin by tumor-necrosis-factor-α-stimulated dermal fibroblasts. Eur J Biochem 1998;253:114-122.
12. MacLean JA, Ownbey R, Luster AD: T cell-dependent regulation of eotaxin in allergen-induced pulmonary eosinophilia. J Exp Med 1996;184:1461-1469.
13. Ying S, Taborda-Barata L, Meng Q, Humbert M, Kay AB: The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: Relationship to eosinophil, T cell, and macrophage recruitment. J Exp Med 1995;181:2153-2159.
14. Marfaing-Koka A, Devergne O, Gorgone G, Portier A, Schall TJ, Galanaud P, Emilie D: Regulation of the production of the RANTES chemokine by endothclial cells. J Immunol 1995;154:1870-1878.
15. Griffiths-Johnson DA, Collins PD, Rossi AG, Jose PJ, Williams TJ: The chemokine eotaxin activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo. Biochem Biophys Commun 1993;197:1167-1172.
16. Ponath PD, Qin S, Ringer DJ, Clark-Lewis I, Wang J, Kassam N, Smith H, Shi X, Gonzalo JA, Newman W, Gutierrez-Ramos JC, Mackay CR: Cloning of the human eosinophil chemoattractant, eotaxin. J Clin Invest 1996;97:604-612.
17. Tepper RI, Pattengale PK, Leder P: Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 1989;57:503-512.
18. Rothenberg ME, Luster AD, Leder P: Murine eotaxin: An eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression. Proc Natl Acad Sci USA 1995;92:8960-8964.
19. Sanz MJ, Ponath PD, Mackay CR, Newman W, Miyasaka M, Tamatani T, Flanagan BF, Lobb RR, Williams TJ, Nourshargh S, Jose PJ: Human eotaxin induces α4 and β2 integrin-dependent eosinophil accumulation in rat skin in vivo: Delayed generation of eotaxin in response to IL-4. J Immunol 1998;160:3569-3576.
20. Steffen M, Abboud M, Potter GK, Yung XP, Moore MAS: Presence of tumor necrosis factor on a related factor in human basophil/mast cells. Immunology 1989;66:445-450.
21. Barks JL, McQuillan JJ, Iademarco MF: TNF-α and IL-4 synergically increase vascular cell adhesion molecule-1 expression in cultured vascular smooth muscle cells. J Immunol 1997; 159:4532-4538.