An efficient synthesis of Boc-aminoacetaldehyde and its application to the synthesis of n-(2-Boc-aminoethyl)glycine esters

Organic Preparations and Procedures International

Volumn 25, Issue 4, 1993, Pages 457-461

  Dueholm, Kim L ^a   Egholm, Michael ^a   Buchardt, Ole ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0345396975     PISSN: 00304948     EISSN: 19455453     Source Type: Journal    
DOI: 10.1080/00304949309457989     Document Type: Article

References (18)

1. E. Uhlmann and A. Peymann, Chem. Rev., 90, 544 (1990).
2. P. E. Nielsen, M. Egholm, R. H. Berg and O. Buchardt, Science, 254, 1497 (1991).
3. M. Egholm, O. Buchardt, P. E. Nielsen and R. H. Berg, J. Am. Chem. Soc., 114, 1895 (1992).
4. M. Egholm, P. E. Nielsen, O. Buchardt and R. H. Berg, J. Am. Chem. Soc., 114, 9677 (1992).
5. S. Liu and R. P. Hanzlik, J. Med. Chem., 35, 1067 (1992).
6. L. De Napoli, A. Evidente, G. Picciali, C. Santacroce and R. Veillone, Phytochemistry, 29, 701 (1990).
7. N. Bischofberger, H. Waldmann, T. Saito, E. S. Simon, W. Lees, M. D. Bednarski and G. M. Whitesides, J. Org. Chem., 53, 3457 (1988).
8. A. Golebiowski, U. Jacobsson, M. Chmielewski and J. Jurczak, Tetrahedron, 43, 599 (1987).
9. S.A. Thompson, P.R. Andrews and R.P. Hanzlik, J. Med. Chem., 29, 104 (1986).
10. R. P. Hanzlik and S. A. Thompson, J. Med. Chem., 27, 711 (1984).
11. A.J. Mancuso and D. Swern, Synthesis, 165 (1981).
12. E. J. Corey and J. W. Suggs, Tetrahedron Lett., 31, 2647 (1975).
13. U. Schmidt, M. Respondek, A. Lieberknecht, J. Werner and P. Fischer, Synthesis, 256 (1989).
14. W. D. Lubell and H Rapoport, J. Am. Chem. Soc., 109, 236 (1987).
15. K. E. Rittie, C. F. Homnick, G. S. Ponticello and B. E. Evans, J. Org. Chem., 47, 3016 (1982).
16. J.-A. Fehrentz and B. Castro, Synthesis, 676 (1983).
17. R. J. Simon, R. S. Kania, R. N. Zuckermann, V. D. Huebner, D. A. Jewell, S. Banville, S. Ng, L. Wang, S. Rosenberg, C. K. Marlowe, D. C. Spellmeyer, R. Tan, A. D. Frankel, D. V. Santi, F. E. Cohen and P. A. Bartlett, Proc. Natl. Acad. Sci. USA, 89, 9367 (1992).
18. Although satifactory (±0.30) data were obtained for the carbon and hydrogen analyses, the results for nitrogen were beyond acceptable limits for 2.