-
1
-
-
0025146426
-
Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-dependent inhibitors
-
Weitz JI, Hudoba M, Massel D, Maraganore J, Hirsh J: Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-dependent inhibitors. J Clin Invest 1990;86:385-391.
-
(1990)
J Clin Invest
, vol.86
, pp. 385-391
-
-
Weitz, J.I.1
Hudoba, M.2
Massel, D.3
Maraganore, J.4
Hirsh, J.5
-
2
-
-
0026434005
-
Heparin
-
Hirsh J: Heparin. N Engl J Med 1991;324:1565-574.
-
(1991)
N Engl J Med
, vol.324
, pp. 1565-1574
-
-
Hirsh, J.1
-
3
-
-
0022521744
-
Kinetics of inhibition of thrombin by hirudin
-
Stone SR, Hofsteenge J: Kinetics of inhibition of thrombin by hirudin. Biochem 1986;25:4622-4628.
-
(1986)
Biochem
, vol.25
, pp. 4622-4628
-
-
Stone, S.R.1
Hofsteenge, J.2
-
4
-
-
0030722727
-
A comparison of recombinant hirudin with a low-molecular-weight heparin to prevent thromboembolic complication after total hip replacement
-
Eriksson BI, Wille-Jorgensen P, Kalebo P, et al: A comparison of recombinant hirudin with a low-molecular-weight heparin to prevent thromboembolic complication after total hip replacement. N Engl J Med 1997;337:1329-1335.
-
(1997)
N Engl J Med
, vol.337
, pp. 1329-1335
-
-
Eriksson, B.I.1
Wille-Jorgensen, P.2
Kalebo, P.3
-
5
-
-
0029101260
-
A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty
-
Serruys PW, Herrman J-PR, Simon R, et al and the Helvetica Investigators: A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. N Engl J Med 1995;333:757-763.
-
(1995)
N Engl J Med
, vol.333
, pp. 757-763
-
-
Serruys, P.W.1
Herrman, J.-P.R.2
Simon, R.3
-
6
-
-
0027497137
-
Initial experience with a direct antithrombin, hirulog, in unstable angina: Anticoagulant, antithrombotic, and clinical effects
-
Lidon RM, Theroux P, Juneau M, Adelman B, Maraganore J: Initial experience with a direct antithrombin, hirulog, in unstable angina: Anticoagulant, antithrombotic, and clinical effects. Circulation 1993;99;1495-1501.
-
(1993)
Circulation
, vol.99
, pp. 1495-1501
-
-
Lidon, R.M.1
Theroux, P.2
Juneau, M.3
Adelman, B.4
Maraganore, J.5
-
7
-
-
0029153842
-
r-Hirudin in unstable angina pectoris: Rationale and preliminary data from the APT pilot study
-
Fox KA: r-Hirudin in unstable angina pectoris: Rationale and preliminary data from the APT pilot study. Eur Heart J 1995;16(suppl D):28-32.
-
(1995)
Eur Heart J
, vol.16
, Issue.SUPPL. D
, pp. 28-32
-
-
Fox, K.A.1
-
8
-
-
0027140468
-
Usefulness and tolerability of hirulog, a direct thrombin inhibitor, in unstable angina pectoris
-
Sharma GV, Lapsley D, Vita JA, Sharma S, Coccio E, Adelman B, Loscalzo J: Usefulness and tolerability of hirulog, a direct thrombin inhibitor, in unstable angina pectoris. Am J Cardiol 1993;72:1357-1360.
-
(1993)
Am J Cardiol
, vol.72
, pp. 1357-1360
-
-
Sharma, G.V.1
Lapsley, D.2
Vita, J.A.3
Sharma, S.4
Coccio, E.5
Adelman, B.6
Loscalzo, J.7
-
9
-
-
0029148676
-
Hirulog in the treatment of unstable angina: Results of the Thrombin Inhibition in Myocardial Ischemia (TIMI) 7 Trial
-
Fuchs J, Cannon CP, and the TIMI 7 Investigators: Hirulog in the treatment of unstable angina: Results of the Thrombin Inhibition in Myocardial Ischemia (TIMI) 7 Trial. Circulation 1995;92:727-733.
-
(1995)
Circulation
, vol.92
, pp. 727-733
-
-
Fuchs, J.1
Cannon, C.P.2
-
10
-
-
0028346249
-
Recombinant hirudin for unstable angina pectoris: A multicenter, randomized angiographic trial
-
Topol EJ, Fuster V, Harrington RA, et al: Recombinant hirudin for unstable angina pectoris: A multicenter, randomized angiographic trial. Circulation 1994;89:1557-1566.
-
(1994)
Circulation
, vol.89
, pp. 1557-1566
-
-
Topol, E.J.1
Fuster, V.2
Harrington, R.A.3
-
11
-
-
0028326748
-
A pilot, early angiographic patency study using a direct thrombin inhibitor as adjunctive therapy to streptokinase in acute myocardial infarction
-
Lidon RM, Théroux P, Lespérance J, Adelman B, Bonan R, Duval D, Levesque J: A pilot, early angiographic patency study using a direct thrombin inhibitor as adjunctive therapy to streptokinase in acute myocardial infarction. Circulation 1994;89:1567-1572.
-
(1994)
Circulation
, vol.89
, pp. 1567-1572
-
-
Lidon, R.M.1
Théroux, P.2
Lespérance, J.3
Adelman, B.4
Bonan, R.5
Duval, D.6
Levesque, J.7
-
12
-
-
0028936602
-
Randomized double-blind comparison of two doses of hirulog with heparin as adjunctive therapy to streptokinase to promote early patency of the infarct-related artery in acute myocardial infarction
-
Théroux P, Perez-Villa F, Waters D, Lespérance J, Shabani F, Bonan R: Randomized double-blind comparison of two doses of hirulog with heparin as adjunctive therapy to streptokinase to promote early patency of the infarct-related artery in acute myocardial infarction. Circulation 1995;91:2132-2139.
-
(1995)
Circulation
, vol.91
, pp. 2132-2139
-
-
Théroux, P.1
Perez-Villa, F.2
Waters, D.3
Lespérance, J.4
Shabani, F.5
Bonan, R.6
-
13
-
-
0028296374
-
A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) 5 trial
-
Cannon CP, McCabe CH, Henry TD, et al: A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) 5 trial. J Am Coll Cardiol 1994;23:993-1003.
-
(1994)
J Am Coll Cardiol
, vol.23
, pp. 993-1003
-
-
Cannon, C.P.1
McCabe, C.H.2
Henry, T.D.3
-
14
-
-
0028795568
-
Initial experience with hirudin and streptokinase in acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) 6 trial
-
Lee LV: Initial experience with hirudin and streptokinase in acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) 6 trial. Am J Cardiol 1995;75:7-13.
-
(1995)
Am J Cardiol
, vol.75
, pp. 7-13
-
-
Lee, L.V.1
-
15
-
-
0029835392
-
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
-
Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators: A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N Engl J Med 1996;335:775-782.
-
(1996)
N Engl J Med
, vol.335
, pp. 775-782
-
-
-
16
-
-
0343580449
-
Comparison of the effects of two doses of recombinant hirudin compared with heparin in patients with acute myocardial ischemia without ST elevation: A randomized trial
-
Organization to Assess Strategies for Ischemic Syndromes (OASIS) Investigators: Comparison of the effects of two doses of recombinant hirudin compared with heparin in patients with acute myocardial ischemia without ST elevation: A randomized trial. Circulation 1997;96:769-777.
-
(1997)
Circulation
, vol.96
, pp. 769-777
-
-
-
17
-
-
0033528281
-
Effects of recombinant hirudin (lepirudin) compared with heparin of death, myocardial infarction, refractory angina, and revacularisation procedures in patients with acute myocardial ischaemia without ST elevation: A randomised trial
-
Organisation to Access Strategies for Ischemic Syndromes (OASIS-2) Investigators: Effects of recombinant hirudin (lepirudin) compared with heparin of death, myocardial infarction, refractory angina, and revacularisation procedures in patients with acute myocardial ischaemia without ST elevation: A randomised trial. Lancet 1999;353:429-438.
-
(1999)
Lancet
, vol.353
, pp. 429-438
-
-
-
18
-
-
0028117846
-
Safety observations from the pilot phase of the randomized r-Hirudin for Improvement of Thrombolysis (HIT-III) study: A study of the Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte
-
Neuhaus KL, von Essen R, Tebbe U, et al: Safety observations from the pilot phase of the randomized r-Hirudin for Improvement of Thrombolysis (HIT-III) study: A study of the Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte. Circulation 1994;90:1638-1642.
-
(1994)
Circulation
, vol.90
, pp. 1638-1642
-
-
Neuhaus, K.L.1
Von Essen, R.2
Tebbe, U.3
-
19
-
-
0028037517
-
Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes
-
GUSTO IIa Investigators: Randomized trial of intravenous heparin versus recombinant hirudin for acute coronary syndromes. Circulation 1994;90:1631-1637.
-
(1994)
Circulation
, vol.90
, pp. 1631-1637
-
-
-
20
-
-
0028092111
-
Hirudin in acute myocardial infarction. Safety report from the thrombolysis and thrombin inhibition in myocardial infarction (TIMI) 9A trial
-
Antman EM, for the TIMI 9A investigators: Hirudin in acute myocardial infarction. Safety report from the thrombolysis and thrombin inhibition in myocardial infarction (TIMI) 9A trial. Circulation 1994;90:1624-1630.
-
(1994)
Circulation
, vol.90
, pp. 1624-1630
-
-
Antman, E.M.1
-
21
-
-
0029835392
-
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndrome
-
The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators. A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndrome. N Engl J Med 1996;335:775-782.
-
(1996)
N Engl J Med
, vol.335
, pp. 775-782
-
-
-
22
-
-
0030679587
-
Meeting highlights: XIX Congress of the European Society of Cardiology
-
Ferguson JJ: Meeting highlights: XIX Congress of the European Society of Cardiology. Circulation 1997;96:3818-3821.
-
(1997)
Circulation
, vol.96
, pp. 3818-3821
-
-
Ferguson, J.J.1
-
23
-
-
0031823150
-
Results from late-breaking clinical trials sessions at ACC '98
-
Alderman EL: Results from late-breaking clinical trials sessions at ACC '98. J Am Coll Cardiol 1998;32:1-7.
-
(1998)
J Am Coll Cardiol
, vol.32
, pp. 1-7
-
-
Alderman, E.L.1
-
24
-
-
0030738111
-
Results from late breaking clinical trials session at ACC '97
-
Cody RJ: Results from late breaking clinical trials session at ACC '97. J Am Coll Cardiol 1997;30:1-7.
-
(1997)
J Am Coll Cardiol
, vol.30
, pp. 1-7
-
-
Cody, R.J.1
-
25
-
-
0030771823
-
Randomized, double-blind comparison of hirulog versus heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO)
-
White HD, Aylward PE, Collins R, et al: Randomized, double-blind comparison of hirulog versus heparin in patients receiving streptokinase and aspirin for acute myocardial infarction (HERO). Circulation 1997;96:2155-2161.
-
(1997)
Circulation
, vol.96
, pp. 2155-2161
-
-
White, H.D.1
Aylward, P.E.2
Collins, R.3
-
26
-
-
0035836541
-
Argatroban Anticoagulant Therapy in Patients with Heparin-Induced Thrombocytopenia
-
Lewis BE, Wallis DE, Berkowitz SD, Matthai WH, Fareed J, Walenga JM, Bartholomew J, Sham R, Lemer RG, Zeigler ZR, Rustagi PK, Jang IK, Rifkin SD, Moran J, Hursting MJ, Kelton JG, for the ARG-911 Study Investigators: Argatroban Anticoagulant Therapy in Patients With Heparin-Induced Thrombocytopenia. Circulation 2001;103:1838-1843.
-
(2001)
Circulation
, vol.103
, pp. 1838-1843
-
-
Lewis, B.E.1
Wallis, D.E.2
Berkowitz, S.D.3
Matthai, W.H.4
Fareed, J.5
Walenga, J.M.6
Bartholomew, J.7
Sham, R.8
Lemer, R.G.9
Zeigler, Z.R.10
Rustagi, P.K.11
Jang, I.K.12
Rifkin, S.D.13
Moran, J.14
Hursting, M.J.15
Kelton, J.G.16
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