Intensified prophylaxis of febrile neutropenia with ofloxacin plus rifampin during severe short-duration neutropenia in patients with lymphoma

Leukemia and Lymphoma

Volumn 34, Issue 5-6, 1999, Pages 585-589

  Muñoz, Luz ^a   Martino, Rodrigo ^a   Subirà, Maricel ^a   Brunet, Salut ^a   Sureda, Anna ^a   Sierra, Jorge ^a  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

Infection; Neutropenia; Ofloxacin; Prophylaxis; Rifampin

Indexed keywords

ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CYTARABINE; ETOPOSIDE; IFOSFAMIDE; NORFLOXACIN; OFLOXACIN; PREDNISOLONE; RIFAMPICIN;

ADOLESCENT; ADULT; AGED; ARTICLE; BACTEREMIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEBRILE NEUTROPENIA; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE COCCI; HOSPITAL ADMISSION; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LENGTH OF STAY; LYMPHOMA; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROPHYLAXIS; PYREXIA IDIOPATHICA;

EID: 0345363271     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428199909058487     Document Type: Article

References (16)

1. Cruciani M, Rampazzo R, Malena M et al. (1996) Prophylaxis with fluoroquinolones for bacterial infections in neutropenic patients: a meta-analysis. Clin Infect Dis, 23, 795-805.
2. Bow EJ, Mandell LA, Louie TJ, Feld R, Palmer M, Zee B, Pater J. (1996) Quinolone-based antibacterial chemoprophylaxis in neutopenic patients: Effect of augmented gram-positive activity on infectious morbidity. Ann Int Med, 125 ,186-190.
3. Hidalgo M, Hornedo J, Lumbreras C et al. (1997) Lack of ability of ciprofloxacin-rifampin prophylaxis to decrease infection-related morbidity in neutropenic patients given cytotoxic therapy and peripheral blood stem cell transplants. Antimicrob Agents Chemother, 41, 1175-1177.
4. Gilbert C, Meisenberg B, Vredesburgh J et al. (1994) Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support. J Clin Oncol, 12, 1005-1011.
5. Thornsberry C, Hill BC, Swenson JM, McDougal LK. (1983) Rifampin: spectrum of antibacterial actibity. Rev Infect Dis, 5(Suppl 3), S412-7.
6. 2) after savage chemotherapy for lymphoma. Bone Marrow Transplant, 20, 855-858.
7. Martino R, Subirà M, Altès A et al. (1998) Effect of discontinuing prophylaxis with norfloxacin in patients with hematologic malignancies and severe neutropenia. Acta Haematol, (99, 206-211).
8. Pizzo PA. (1993) Management of fever in patients with cancer and treatment-induced neutropenia. N Engl J Med, 328, 1323-1332.
9. Carratalá J, Fernández-Sevilla A, Tubau F, Callis M, Gudiol F. (1995) Emergence of quinolone-resistant Escherichia coli bacteremia in neutropenic patients with cancer who have received prophylactic norfloxacin. Clin Infect Dis, 20, 557-560.
10. Carratalá J, Fernández-Sevilla A, Tubau F, Dominguez MA, Gudiol F. (1996) Emergence of fluoroquinolone-resistant Escherichia coli in fecal flora of cancer patients receiving norfloxacin prophylaxis. Antimicrob Agents Chemother, 40, 503-505.
11. Kotilainen P, Nikoskelainen J., Huovinen P. (1990) Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin. J Infect Dis, 161, 41-44.
12. Hugues WT, Armstrong D, Bodey GP, et al. (1997) Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. Clin Infect Dis, 25, 551-573.
13. Maschmeyer G, Hiddermann W, Link H et al. (1997) Management of infections during intensive treatment of hematologic malignancies. Ann Hematol, 75, 9-16.
14. de Marie S, van den Broek PJ, Willemze R, van Furth R. (1993) Strategy for antibiotic therapy in febrile neutropenic patients on selective antibiotic decontamination. Eur J Clin Microbiol Infect Dis, 12, 897-906.
15. Bauerfeind A, Abele-Horn M, Emmerling P, Jungwirth R. (1994) Multiclonal emergence of ciprofloxacin-resistant clinical isolates of Escherichia coli and Klebsiella pneumonia. J Antimicrob Chemother, 34, 1074-1076.
16. Pegues D, Colby C, Hibberd P et al. (1998) The epidemiology of resistance to ofloxacin and oxacillin among clincal coagulase-negative staphylococcal isolates: analysis of risk factors and strain types. Clin Infect Dis. 26, 72-9.