MRI measurement of cell volume fraction in the perfused rat hippocampal slice

Magnetic Resonance in Medicine

Volumn 42, Issue 3, 1999, Pages 603-607

  Buckley, David L ^a,b   Jonathan D, Bui ^a   Phillips, M Ian ^a   Blackband, Stephen J ^a,b,c  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Brain slice; Cell volume; Gadolinium; T1 relaxation

Indexed keywords

CELLS; CEREBROSPINAL FLUID; GADOLINIUM; MAGNETIC RESONANCE IMAGING; RATS; VOLUME FRACTION;

BRAIN SLICES; CELL DENSITY; CELL VOLUME; CELL VOLUME FRACTION; DISTRIBUTION VOLUME; HIPPOCAMPAL SLICE; MEAN CELL VOLUMES; T1 RELAXATION;

CYTOLOGY;

GADODIAMIDE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CELL DENSITY; CELL VOLUME; HIPPOCAMPUS; MATHEMATICAL COMPUTING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT; SIGNAL PROCESSING; TECHNIQUE;

EID: 0345362995     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1522-2594(199909)42:3<603::AID-MRM25>3.0.CO;2-Q     Document Type: Article

References (21)

1. Nicholson C, Sykova E. Extracellular spaco structure revealed by diffusion analysis. Trends Neurosci 1998;21:207-215.
2. Pérez-Pinzón MA, Tao L, Nicholson C. Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia. J Neurophysiol 1995;74:565-573.
3. Ting YT, Degani H. Energetics and glucose metabolism in hippocampal slices during depolarization: P-31 and C-13 NMR studies. Brain Res 1993;610:16-23.
4. 2+ and energy metabolism in superfused brain slices. Biochem Soc Trans 1994;22:988-991.
5. Pirttila TM, Kauppinen RA. Regulation of intracellular pH in guinea pig cerebral cortex ex-vivo studied by P-31 and H-1 nuclear magnetic resonance spectroscopy: role of extracellular bicarbonate and chloride. J Neurochem 1994;62:656-664.
6. Blackband SJ, Bui JD, Buckley DL, Zelles T, Plant HD, Inglis BA, Phillips MI. MR microscopy of perfused brain slices. Magn Reson Med 1997;38:1012-1015.
7. Buckley DL, Bui JD, Phillips MI, Zelles T, Inglis BA, Plant HD, Blackband SJ. The effect of ouabain on water diffusion in the rat hippocampal slice measured by high resolution NMR imaging. Magn Reson Med 1999;41:137-142.
8. Moseley ME, Cohen Y, Mintorovitch J, Chileuitt L, Shimizu H, Kucharczyk J, Wendland MF, Weinstein PR. Early detection of regional cerebral ischemia in cats: comparison of diffusion and T2-weighted MRI and spectroscopy. Magn Reson Med 1990;14:330-346.
9. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton-exchange rates in tissue. Magn Reson Med 1994;32:66-76.
10. Normann PT, Hals PA. In vivo stability and excretion of gadodiamide (GdDTPA-BMA), a hydrophilic gadolinium complex used as a contrast enhancing agent for magnetic resonance imaging. Eur J Drug Metab Pharm 1995;20:307-313.
11. Palovcik RA, Phillips MI. A biphasic excitatory response of hippocampal neurons to gonadotropin releasing hormone. Neuroendocrinology 1986;44:137-141.
12. Bui JD, Buckley DL, Phillips MI, Blackband SJ. In: Blumler P, Blumich B, Botto RE, Fukushima E, editors. Spatially resolved magnetic resonance. Weinheim: Wiley-VCH; 1998. p 337.
13. 1) relaxation. Magn Reson Imag 1986;4:285-291.
14. Larcombe-McDouall JB, Seo Y, Steward MC. Continuous measurement of cell volume changes in perfused rat salivary glands by proton NMR. Magn Reson Med 1994;31:131-138.
15. Donahue KM, Weisskoff RM, Parmelee DJ, Callahan RJ, Wilkinson RA, Mandeville JB, Rosen BR. Dynamic Gd-DTPA enhanced MRI measurement of tissue cell-volume fraction. Magn Reson Med 1995;34:423-432.
16. Newman GC, Hospod FE, Qi H, Patel H. Effects of dextran on hippocampal brain slice water, extracellular-space, calcium kinetics and histology. J Neurosci Meth 1995;61:33-46.
17. Barsky D, Putz B, Schulten K. Theory of heterogeneous relaxation in compartmentalized tissues. Magn Reson Med 1997;37:666-675.
18. Stanisz GJ, Szafer A, Wright GA, Henkelman RM. An analytical model of restricted diffusion in bovine optic nerve. Magn Reson Med 1997;37: 103-111.
19. Pfeuffer J, Flogel U, Dreher W, Leibfritz D. Restricted diffusion and exchange of intracellular water: theoretical modelling and diffusion time dependence of H-1 NMR measurements on perfused glial cells. NMR Biomed 1998;11:19-31.
20. Huang R, Somjen GG. The effect of graded hypertonia on interstitial volume, tissue resistance and synaptic transmission in rat hippocampal tissue slices. Brain Res 1995;702:181-187.
21. Pirkle JL, Ashley DL, Goldstein JH, Pulse nuclear magnetic resonance measurements of water exchange across the erythrocyte membrane employing a low Mn concentration. Biophys J 1979;25:389-406.