Calibrated automated thrombin generation in frozen-thawed platelet-rich plasma to detect hypercoagulability

Pathophysiology of Haemostasis and Thrombosis

Volumn 33, Issue 1, 2003, Pages 23-29

  Regnault, Véronique ^a,d   Beguin, Suzette ^c   Lecompte, Thomas ^a,b  

^a UNIVERSITÉ DE LORRAINE   (France)

^b UNIVERSITY HOSPITAL OF NANCY   (France)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d INSERM   (France)

Author keywords

Activated protein C; Factor VIII; Platelets; Thrombin generation

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 8; RECOMBINANT THROMBOPLASTIN;

ARTICLE; CALIBRATED AUTOMATED THROMBOGRAM; CALIBRATION; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIAGNOSTIC APPROACH ROUTE; FREEZING; HUMAN; HYPERCOAGULABILITY; LABORATORY AUTOMATION; NORMAL HUMAN; PRIORITY JOURNAL; THAWING; THROMBIN TIME; THROMBOCYTE; THROMBOCYTE RICH PLASMA; THROMBOSIS;

AUTOMATION; BLOOD COAGULATION TESTS; BLOOD PRESERVATION; CALIBRATION; COUMARINS; CRYOPRESERVATION; ENZYME ACTIVATION; FACTOR VIII; FLUORESCENT DYES; FLUOROMETRY; HUMANS; OLIGOPEPTIDES; PLASMA; PLATELET COUNT; PROTEIN C; RISK FACTORS; SENSITIVITY AND SPECIFICITY; THROMBIN; THROMBOPHILIA;

EID: 0345356192     PISSN: 14248832     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071638     Document Type: Article

References (22)

1. Laffan M, Tuddenham E: Assessing thrombotic risk. BMJ 1998;317:520-523.
2. Hemker HC, Béguin S: Phenotyping the clotting system. Thromb Haemost 2000;84:747-751.
3. Regnault V, Béguin S, Wahl D, De Maistre E, Hemker HC, Lecompte T: Thrombinography shows acquired resistance to activated protein C in patients with lupus anticoagulants. Thromb Haemost 2003;89:208-212.
4. Heemskerk JWM, Bevers EM, Lindhout T: Platelet activation and blood coagulation. Thromb Haemost 2002;88:186-193.
5. Monroe DM, Hoffman M, Roberts HR: Platelets and thrombin generation. Arterioscler Thromb Vasc Biol 2002;22:1381-1389.
6. Soria JM, Almasy L, Souto JC, Buil A, Martinez-Sanchez E, Mateo J, Borell M, Stone WH, Lathrop M, Fontcuberta J, Blangero J: A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility. Blood 2003;101:163-167.
7. Gomi K, Zushi M, Honda G, Kawahara S, Matsuzaki O, Kanabayashi T, Yamamoto I, Mauryama I, Suzuki K: Antithrombotic effect of recombinant human thrombomodulin on thrombin-induced thromboembolism in mice. Blood 1990;75:1396-1399.
8. Regnault V, De Maistre E, Geschier C, Briquel ME, André E, Stoltz JF, Lecompte T: A new fast one-step immunopreparation for activated protein C. Thromb Haemost 1995;73:1365.
9. Dahlbäck B, Carlsson M, Svensson PJ: Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 1993;90:1004-1008.
10. Hemker HC, Giesen PLA, Ramjee M, Wagenvoord R, Béguin S: The thrombogram: monitoring thrombin generation in platelet rich plasma. Thromb Haemost 2000;83:589-591.
11. Hemker HC, Giesen P, Al Dieri R, Regnault V, de Smedt E, Wagenvoord R, Lecompte T, Béguin S: Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 2003;33:4-15.
12. Hemker HC, Giesen P, Al Dieri R, Regnault V, de Smedt E, Wagenvoord R, Lecompte T, Béguin S: Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiol Haemost Thromb 2003;33:4-15.
13. Rosing J, van Rijn JLMM, Bevers EM, van Dieijen G, Comfurius P, Zwaal RF: The role of activated human platelets in prothombin and factor X activation. Blood 1985;65:319-332.
14. Mann KG, Butenas S, Brummel K: The dynamics of thrombin formation. Arterioscler Thromb Vasc Biol 2003;23:17-25.
15. Taylor FB, Peer GT, Lockhart MS, Ferrell G, Esmon CT: Endothelial cell protein C receptor plays an important role in protein C activation in vivo. Blood 2001;97:1685-1688.
16. Hampton JW, Matthew C: Similarities between baboon and human blood clotting. J Appl Physiol 1966;21:1713-1716.
17. Taube J, McWilliam N, Luddington R, Byrne C, Baglin T: Activated protein C resistance: Effect of platelet activation, platelet-derived microparticles, and atherogenic lipoproteins. Blood 1999;93:3792-3797.
18. Jane SM, Mitchell CA, Hau L, Salem HH: Inhibition of activated protein C in platelets. J Clin Invest 1989;83:222-226.
19. Nishioka J, Ning M, Hayashi T, Suzuki K: Protein C inhibitor secreted from activated platelets efficiently inhibits activated protein C on phosphatidylethanolamine of platelet membrane and microvesicles. J Biol Chem 1998;273:11281-11287.
20. Smirnov MD, Esmon CT: Phosphatidylethanolamine incroporation into vesicles selectively enhances factor Va inactivation by activated protein C. J Biol Chem 1994;269:816-819.
21. Koster T, Blann AD, Briet E, Vandenbroucke JP, Rosendaal FR: Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis. Lancet 1995;345:152-155.
22. Kamphuisen PW, Eikenboom JCJ, Bertina RM: Elevated factor VIII levels and the risk of thrombosis. Arterioscler Thromb Vasc Biol 2001;21:731-738.