Role of prostaglandins and nitric oxide in gastrointestinal hyperemia of diabetic rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 270, Issue 4 33-4, 1996, Pages

  Goldin, Eran ^a,c   Casadevall, Maria ^a   Mourelle, Marisa ^a   Cirera, Isabel ^a   Elizalde, Josep I ^a   Panés, Julian ^a   Casamitjana, Roser ^a   Guth, Paul ^a   Piqué, Josep M ^a,d   Terés, Josep ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d HOSPITAL CLÍNIC   (Spain)

Author keywords

diabetes; gastric blood flow; glucagon; mesenteric blood flow; somatostatin

Indexed keywords

GLUCAGON; NITRIC OXIDE; PROSTAGLANDIN; STREPTOZOCIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD VISCOSITY; BLOOD VOLUME; CONTROLLED STUDY; DIABETES MELLITUS; HEMATOCRIT; HYPEREMIA; HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; STREPTOZOCIN DIABETES; VASODILATATION;

EID: 0345309101     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.4.g684     Document Type: Article

References (38)

1. Bhardwaj, R., and P. K. Moore. Increased vasodilator response to acetylcholine of renal blood vessels from diabetic rats. J. Pharm. Pharmacol. 40: 739-742, 1988.
2. Bohlen, H. G., and K. D. Harkins. Early arteriolar and capillary changes in streptozolocin induced diabetic rats and intraperitoneal hyperglycemic rats. Diabetologia 22: 344-348, 1982.
3. Cameron, N. E., M. A. Cotter, and P. A. Low. Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits. Am. J. Physiol. 261 (Endocrinol Metab. 24): E1-E8, 1981.
4. Chang, W. P., E. Dimitriadis, T. Allen, M. E. Dunlop, M. Cooper, and R. G. Larkins. The effect of aldolase reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus. Diabetologia. 34: 225-231, 1991.
5. Christensen, N. J. A reversible vascular abnormality associated with diabetic ketosis. Clin. Sci. Lond. 39: 539-548, 1970.
6. Davi, G., I. Catalane, M. Averna, A. Notarbartolo, A. Strano, G. Ciabattoni, and C. Patrono. Thromboxane biosynthesis and platelet function in type II diabetes mellitus. N. Engl. J. Med. 322: 1769-1774, 1990.
7. Diederich, D., J. Skopec, A. Diederich, and F. X. Dai. Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H1153-H1161, 1994.
8. Drost, C. J. Vessel diameter independent volume flow measurements using ultrasound. Proc. San Diego Biomed. Symp. 17: 299-302, 1978.
9. Feldman, M., and L. R. Schiller. Disorders of gastrointestinal motility associated with diabetes mellitus. Ann. Int. Med. 98: 378-384, 1983.
10. Gundersen, H. J. G. Peripheral blood flow and metabolic control in juvenile diabetes. Diabetologia 10: 225-231, 1974.
11. Haggendale, E., B. Steen, and A. Svanborg. Blood flow in subcutaneous fat tissue in patients with diabetes mellitus. Acta Med. Scand. 187: 49-53, 1970.
12. Harris, K. H., and K. M. MacLeod. Influence of the endothelium on contractile responses of arteries from diabetic rats. Eur. J. Pharmacol 153: 55-64, 1988.
13. Hill, M. A., and R. G. Larkins. Alterations in distribution of cardiac output in experimental diabetes in rats. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H571-H580, 1989.
14. Hostetter, T. H., H. G. Rennke, and B. M. Brenner. The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies. Am. J. Med. 72: 375-380, 1982.
15. 15a.Houben, A. J., A. C. Nieuwenhuijzen, E. Bouhouch, D. W. Slaaf. and N. C. Schaper. Peripheral macro and microcirculation in short-term insulin dependent diabetes mellitus: the role of prostaglandins in early hemodynamic changes. Eur. J. Clin. Invest. 23: 662-667, 1993.
16. Houben, A. J., N. C. Schaper, D. W. Slaaf, G. J. Tangelder, and A. C. Nieuwenhuijzen Kruseman. Skin blood cell flux in insulin-dependent subjects in relation with retinopathy or incipient nephropathy. Eur. J. Clin. Invest. 22: 67-72, 1992.
17. Jeremy, J. Y., D. P. Mikhilidis, and P. Dandona. Simulating the diabetic environment modifies in vitro prostacyclin synthesis. Diabetes 32: 217-221, 1983.
18. Kamata, K., N. Miyata, and Y. Yasuya. Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats. Br. J. Pharmacol. 97: 614-618, 1989.
19. Kiff, R. J., S. M. Gardiner, A. M. Compton, and T. Bennett. The effects of endothelin-1 and N-nitro-L-arginine methyl ester on regional haemodynamies in conscious rats with streptozotocin-induced diabetes mellitus. Br. J. Pharmacol. 103: 1321-1326, 1991.
20. Knowles, R. G., M. Merret, M. Salter, and S. Moncada. Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. Biochem. J. 270: 833-836, 1990.
21. Kohner, E. M., A. M. Hamilton, S. J. Saunders, B. A. Sutcliffe, and C. J. Bulpitt. The retinal blood flow in diabetes. Diabetologia 11: 27-33, 1975.
22. Korthuis, R. J., J. N. Benoit, P. R. Kvietys, H. M. Laughlin, A. E. Taylor, and D. N. Granger. Intestinal hyperemia in experimental diabetes mellitus. Am. J. Physiol. 253 (Gastrointest. Liver Physiol. 16): G26-G32, 1987.
23. Kravetz, D., M. Arderieu, J. Bosch, J. Fuster, J. Visa, R. Casamitjana, and J. Rodes. Hyperglucagonemia and hyperkinetic circulation following portocaval shunt in the rat. Am. J. Physiol. 252 (Gastrointest. Liver Physiol. 15): G257-G261, 1987.
24. Kravetz, D., M. T. Arderiu, J. Bosch, C. Piera, J. Setoain, and J. Rodes. Increased plasma volume on two models of portal hypertension in the rat: cirrhosis of the liver and partial portal vein ligation. Rev. Esp Fisiol. 43: 179-184, 1987.
25. Lestradet, H., L. Papoz, C. Hellouin de Menibus, F. Levavassuer, J. Besse, L. Billaud, F. Battistelli, P. Trie, and F. Lestradet. Long-term study of mortality and vascular complications in juvenile-onset (Type I) diabetes. Diabetes 30: 175-179, 1981.
26. Lowry, O. H., M. J. Rosenbrough, A. L. Farr, and R. J. Randall. Protein measurement with folin phenol reagent. J. Biol. Chem. 193: 265-270, 1951.
27. Lucas, P. D., and J. M. Foy. Effects of experimental diabetes and genetic obesity on regional blood flow in the rat. Diabetes 26: 786-792, 1972.
28. Martinez-Cuesta, M. A., H. Massuda, B. J. R. Whittle, and S. Moncada. Impairment of nitrergic-mediated relaxation of rat isolated duodenum by experimental diabetes. Br. J. Pharmacol. 114: 919-924, 1995.
29. Mayhan, W. G. Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus. Am. J. Physiol. 256 (Heart Circ, Physiol. 25): H621-H625, 1989.
30. Nowak, T. V., B. Harrington, J. P. Weisbruch, and J. H. Kalbleisch. Structural and functional characteristics of muscle from diabetic rodent small intestine. Am. J. Physiol. 258 (Gastrointest. Liver Physiol. 21): G690-G698, 1990.
31. Pillion, D. J., R. L. Jemkins, J. A. Atchison, C. R. Stockard, R. S. Clements, Jr., and W. E. Grizzle. Paradoxical organ-specific adaptations to streptozotocin diabetes mellitus in adult rats. Am. J. Physiol. 254 (Endocrinol. Metab. 17): E749-E755, 1988.
32. Pique, J. M., F. W. Leung, H. W. Tan, E. Livingston, O. U. Scremin, and P. Guth. Gastric mucosal blood flow response to stimulation and inhibition of gastric acid secretion. Gastroenterology 95: 642-650, 1988.
33. Tomlinson, K. C., S. M. Gardiner, R. A. Hebden, and T. Bennett. Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system. Pharmacol. Rev. 44: 103-150, 1992.
34. Tooke, J. E. The microcirculation in diabetes. Diabetic Med. 4: 189-196, 1987.
35. Wegener, M., G. Borsch, J. Schaffstein, C. Luerweg, and F. Leverkus. Gastrointestinal transit disorders in patients with insulin treated diabetes mellitus. Dig. Dis. Sci. 8: 23-26, 1990.
36. White, R. E., and G. O. Carrier. Supersensitivity and endothelium dependency of histamine induced relaxation in mesenteric arteries isolated from diabetic rats. Pharmacology 33: 34-38, 1986.
37. Whittle, B. J. R., and J. R. Vane. Prostanoids as regulators of gastrointestinal function. In: Physiology of the Gastrointestinal Tract (2nd ed.), edited by L. R. Johnson. New York: Raven, 1987, vol. I, p. 143-180.
38. Yrle, L. F., J. K. Smith, J. N. Benoit, D. N. Granger, and R. J. Korthuis. Role of glucagon in intestinal hyperemia associated with early experimental diabetes mellitus. Am. J. Physiol. 255 (Gastrointest. Liver Physiol. 18): G542-G546, 1988.