Does the release of acetylcholine in septal slices originate from intrinsic cholinergic neurons bearing p75NTR receptors? A study using 192 IgG-saporin lesions in rats

Neuroscience

Volumn 122, Issue 4, 2003, Pages 1059-1071

  Birthelmer, A ^a   Lazaris, A ^b   Riegert, C ^b   Marques Pereira, P ^b   Koenig, J ^b   Jeltsch, H ^b   Jackisch, R ^a   Cassel, J C ^a,b,c  

^a Inst F Experimentelle Klin P   (Germany)

^b Centre de Neurochimie   (France)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Diagonal band of Broca; Immunotoxic lesions; Lateral septum; Medial septum; Release; Superfusion

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ATROPINE; AUTORECEPTOR; BRAIN MONOAMINE; BRAIN RECEPTOR; CHOLINE ACETYLTRANSFERASE; IMMUNOGLOBULIN; IMMUNOTOXIN; PHYSOSTIGMINE DERIVATIVE; PHYSOSTIGMINE HEMISULFATE; PROTEIN P75 NTR RECEPTOR; SAPORIN; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN LEVEL; BRAIN REGION; BRAIN SLICE; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; DIAGONAL BAND OF BROCA; DISEASE SEVERITY; ELECTROSTIMULATION; ENZYME ACTIVITY; EVOKED RESPONSE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SEPTUM PELLUCIDUM;

EID: 0345304248     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2003.09.001     Document Type: Article

References (37)

1. Amaral D.G., Kurz J. An analysis of the origins of the cholinergic and noncholinergic septal projections to the hippocampal formation of the rat. J Comp Neurol. 240:1985;37-59.
2. Bender R., Plaschke M., Naumann T., Wahle P., Frotscher M. Development of cholinergic and GABAergic neurons in the rat medial septum different onset of choline acetyltransferase and glutamate decarboxylase mRNA expression . J Comp Neurol. 372:1996;204-214.
3. Berger-Sweeney J., Heckers S., Mesulam M.M., Wiley R.G., Lappi D.A., Sharma M. Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis. J Neurosci. 14:1994;4507-4519.
4. Bialowas J., Frotscher M. Choline acetyltransferase-immunoreactive neurons and terminals in the rat septal complex a combined light and electron microscopic study . J Comp Neurol. 259:1987;298-307.
5. Birthelmer A., Dommes E., Jeltsch H., Cassel J.C., Jackisch R. Septal grafts and evoked acetylcholine release in the rat hippocampus after 192 IgG-saporin lesions. Neuroreport. 13:2002;973-976.
6. Birthelmer A., Ehret A., Amtage F., Forster S., Lehmann O., Jeltsch H., Cassel J.C., Jackisch R. Neurotransmitter release and its presynaptic modulation in the rat hippocampus after selective damage to cholinergic or/and serotonergic afferents. Brain Res Bull. 59:2003;371-381.
7. Birthelmer A., Lazaris A., Schweizer T., Jackisch R., Cassel J.C. Presynaptic regulation of neurotransmitter release in the cortex of aged rats with differential memory impairments. Pharmacol Biochem Behav. 75:2003;147-162.
8. Birthelmer A., Stemmelin J., Jackisch R., Cassel J.C. Presynaptic modulation of acetylcholine, noradrenaline and serotonin release in the hippocampus of aged rats with various levels of memory impairments. Brain Res Bull. 60:2003;283-296.
9. Brauer K., Seeger G., Hartig W., Rossner S., Poethke R., Kacza J., Schliebs R., Bruckner G., Bigl V. Electron microscopic evidence for a cholinergic innervation of GABAergic parvalbumin-immunoreactive neurons in the rat medial septum. J Neurosci Res. 54:1998;248-253.
10. Cheramy A., Leviel V., Glowinski J. Dendritic release of dopamine in the substantia nigra. Nature. 289:1981;537-542.
11. Consolo S., Bertorelli R., Forloni G.L., Butcher L.L. Cholinergic neurons of the pontomesencephalic tegmentum release acetylcholine in the basal nuclear complex of freely moving rats. Neuroscience. 37:1990;717-723.
12. Disko U., Haaf A., Gazyakan E., Heimrich B., Jackisch R. Postnatal development of muscarinic autoreceptors in the rat brain lateral and medial septal nuclei and the diagonal band of Broca . Dev Brain Res. 114:1999;1-8.
13. Disko U., Haaf A., Heimrich B., Jackisch R. Postnatal development of muscarinic autoreceptors modulating acetylcholine release in the septohippocampal cholinergic system II. Cell body region: septum . Dev Brain Res. 108:1998;31-37.
14. Ellman G.L., Cortney K.D., Andres V., Feather-Stone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol. 7:1961;88-95.
15. Fonnum F. A rapid radiochemical method for the determination of choline acetyltransferase. J Neurochem. 24:1975;407-409.
16. Geffen L.B., Jessell T.M., Cuello A.C., Iversen L.L. Release of dopamine from dendrites in rat substantia nigra. Nature. 260:1976;258-260.
17. Gould E., Woolf N.J., Butcher L.L. Postnatal development of cholinergic neurons in the rat I. Forebrain . Brain Res Bull. 27:1991;767-789.
18. Häge B., Frotscher M., Naumann T. Activity of choline acetyltransferase in the rat medial septal nucleus following fimbria-fornix transection or selective immunolesioning with 192 IgG-saporin. Neurosci Lett. 205:1996;119-122.
19. Hallanger A.E., Wainer B.H. Ascending projections from the pedunculopontine tegmental nucleus and the adjacent mesopontine tegmentum in the rat. J Comp Neurol. 274:1988;483-515.
20. Heckers S., Ohtake T., Wiley R.G., Lappi D.A., Geula C., Mesulam M.M. Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor. J Neurosci. 14:1994;1271-1289.
21. Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques a comparison between ABC and unlabeled antibody (PAP) procedures . J Histochem Cytochem. 29:1981;577-580.
22. Jakab R.L., Leranth C. Septum. Paxinos G. The rat nervous system. 1995;405-442 Academic Press, San Diego.
23. Kimura H., Tago H., Akiyama H., Hersh L.B., Tooyama I., McGeer P.L. Choline acetyltransferase immunopositive neurons in the lateral septum. Brain Res. 533:1990;165-170.
24. Lehmann O., Bertrand F., Jeltsch H., Morer M., Lazarus C., Will B., Cassel J.C. 5,7-DHT-induced hippocampal 5-HT depletion attenuates behavioural deficits produced by 192 IgG-saporin lesions of septal cholinergic neurons in the rat. Eur J Neurosci. 15:2002;1991-2006.
25. Lehmann O., Grottick A., Cassel J.C., Higgins G. A double dissociation between serial reaction time and radial maze performance in rats subjected to 192 IgG-saporin lesions of the nucleus basalis and/or the septal region. Eur J Neurosci. 18:2003;651-666.
26. Lehmann O., Jeltsch H., Lazarus C., Tritschler L., Bertrand F., Cassel J.C. Combined 192 IgG-saporin and 5,7-dihydroxytryptamine lesions in the male rat brain a neurochemical and behavioral study . Pharmacol Biochem Behav. 72:2002;899-912.
27. Lewis P.R., Shute C.C., Silver A. Confirmation from choline acetylase analyses of a massive cholinergic innervation to the rat hippocampus. J Physiol. 191:1967;215-224.
28. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J Biol Chem. 193:1951;265-275.
29. Mesulam M.M., Mufson E.J., Levey A.I., Wainer B.H. Cholinergic innervation of cortex by the basal forebrain cytochemistry andcortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey . J Comp Neurol. 214:1983;170-197.
30. Moor E., DeBoer P., Auth F., Westerink B.H. Characterisation of muscarinic autoreceptors in the septo-hippocampal system of the rat a microdialysis study . Eur J Pharmacol. 294:1995;155-161.
31. NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons. J Neurosci. 22:2002;2409-2418.
32. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1986;Academic Press, New York.
33. Sofroniew M.V., Pearson R.C., Powell T.P. The cholinergic nuclei of the basal forebrain of the rat normal structure, development and experimentally induced degeneration . Brain Res. 411:1987;310-331.
34. Suhr R., Balse E., Haaf A., Kelche C., Cassel J.C., Jackisch R. Modulation of acetylcholine and 5-hydroxytryptamine release in hippocampal slices of rats with fimbria-fornix lesions and intrahippocampal grafts containing cholinergic and/or serotonergic neurons. Brain Res Bull. 50:1999;15-25.
35. Torres E.M., Perry T.A., Blockland A., Wilkinson L.S., Wiley R.G., Lappi D.A., Dunnet S.B. Behavioural, histochemical and biochemical consequences of selective immunolesions in discrete regions of the basal forebrain cholinergic system. Neuroscience. 63:1994;95-122.
36. Woolf N.J., Butcher L.L. Cholinergic systems in the rat brain III. Projections from the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basal forebrain . Brain Res Bull. 16:1986;603-637.
37. Wrenn C.C., Wiley R.G. The behavioral functions of the cholinergic basal forebrain lessons from 192 IgG-saporin . Int J Dev Neurosci. 16:1998;595-602.