Cortical electrical stimulation combined with rehabilitative training: Enhanced functional recovery and dendritic plasticity following focal cortical ischemia in rats

Neurological Research

Volumn 25, Issue 8, 2003, Pages 780-788

  Adkins Muir, DeAnna L ^a   Jones, Theresa A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Microtubule associated protein 2 (MAP2); Montoya staircase test; Motor cortex; Motor learning; Stroke plasticity; Subdural electrical stimulation

Indexed keywords

CYTOSKELETON PROTEIN; ENDOTHELIN 1; MICROTUBULE ASSOCIATED PROTEIN 2;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN DEPTH STIMULATION; BRAIN ISCHEMIA; CONTROLLED STUDY; IMMUNOREACTIVITY; MALE; MONTOYA STAIRCASE TEST; MOTOR PERFORMANCE; NERVE CELL PLASTICITY; NONHUMAN; RAT; REVIEW; SENSORIMOTOR CORTEX; TASK PERFORMANCE;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN ISCHEMIA; CELL COUNT; CEREBRAL CORTEX; CORPUS STRIATUM; DENDRITES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; ELECTRODES; ENDOTHELIN-1; FORELIMB; IMMUNOHISTOCHEMISTRY; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR SKILLS; NEURONAL PLASTICITY; RATS; RATS, LONG-EVANS; RECOVERY OF FUNCTION; SENSORY THRESHOLDS; STAINING AND LABELING;

EID: 0345299779     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164103771953853     Document Type: Review

References (43)

1. Tsubokawa T, Katayama Y, Yamamoto T, Hirayama T, Koyama S. Chronic motor cortex stimulation in patients with thalamic pain. J Neurosurgery 1993; 78: 393-401
2. Katayama Y, Fukaya C, Yamamoto T. Control of poststroke involuntary and voluntary movement disorders with deep brain or epidural cortical stimulation. Stereotact Funct Neurosci 1997; 69: 73-79
3. Canavero S, Bonicalzi V, Paolotti R, Castellano G, Greco-Crasto S, Rizzo L, Davini O, Maina R. Therapeutic extradural cortical stimulation for movement disorders: A review. Neurol Res 2003; 25: 118-22
4. Nguyen JP, Pollin B, Feve A, Geny C, Cesaro P. Improvement of action tremor by chronic cortical stimulation. Movement Disord 1996; 11: 489-494
5. Pascual-Leone A, Valls-Sole J, Brasil-Neto JP, Cammarota A, Grafman J, Hallett M. Akinesia in Parkinson's disease. II. Effects of subthreshold repetitive transcranial motor cortex stimulation. Neurology 1994; 44: 892-898
6. Cantello R, Tarletti R, Civardi C. Transcranial magnetic stimulation and Parkinson's disease. Brain Res Rev 2002; 38: 309-327
7. Pascual-Leone A, Tarazona F, Catala MD Applications of transcranial magnetic stimulation in studies on motor learning. Electroencephalogr Clin Neurophysiol Suppl 1999; 51: 157-161
8. Nudo RJ, Jenkins WM, Merzenich MM. Repetitive microstimulation alters the cortical representation of movements in adult rats. Somatosens Mot Res 1990; 7: 463-483
9. VandenBerg PM, Hogg TM, Kleim JA, Whishaw IQ. Long-Evans rats have a larger cortical topographic representation of movement than Fischer-344 rats: A microstimulation study of motor cortex in naive and skilled reaching-trained rats. Brain Res Bull 2002; 59: 197-203
10. Teskey GC, Monfils MH, VandenBerg PM, Kleim JA. Motor map expansion following repeated cortical and limbic seizures is related to synaptic potentiation. Cereb Cortex 2002; 1: 98-105
11. Johansson BB. Brain plasticity and stroke rehabilitation. Stroke 2000; 31: 223-230
12. Vandenberg PM, Kleim JA. The ontogeny of post-ischemic diaschisis. Soc Neurosi Abstr 2001; 27: 761
13. Nudo RJ, Wise BM, SiFuentes F, Milliken GW. Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science 1996; 272: 1791-1794
14. Jones TA, Chu CJ, Grande LA, Gregory AD. Motor skills training enhances lesion-induced structural plasticity in the motor cortex of adult rats. J Neurosci 1999; 19: 10153-10163
15. Biernaskie J, Corbett D. Enriched rehabilitative training promotes improved forelimb motor function and enhanced dendritic growth after focal ischemic injury. J Neurosci 2000; 21: 5272-5280
16. Chu CJ, Jones TA. Experience-dependent structural plasticity in cortex heterotopic to focal sensorimotor cortical damage. Expl Neurol 2002; 166: 403-414
17. Riolobos AS, Heredia M, de la Fuente JA, Criado JM, Yajeya J, Campos J, Santacana M. Functional recovery of skilled forelimb use in rats obliged to use the impaired limb after grafting of the frontal cortex lesion with homotopic fetal cortex. Neurobiol Learn Mem 2001; 75: 274-292
18. Xerri C, Zennou-Azogui Y. Influence of the postlesion environment and chronic piracetam treatment on the organization of the somatotopic map in the rat primary somatosensory cortex after focal cortical injury. Neuroscience 2003; 118: 161-177
19. Montoya CP, Campbell-Hope LJ, Pemberton KD, Dunnett SB. The 'staircase test': A measure of independent forelimb reaching and grasping abilities in rats. J Neurosci Meth 1991; 36: 219-228
20. Whishaw IQ, Woodward NC, Miklyaeva E, and Pellis SM. Analysis of limb use by control rats and unilateral DA-depleted rats in the Montoya staircase test: movements, impairments and compensatory strategies. Behav Brain Res 1997; 89: 167-177
21. Schoenfeld TA, Obar RA. Diverse distribution and function of fibrous microtubule-associated proteins in the nervous system. Int Rev Cytol 1994; 151: 67-137
22. Sánchez C, Díaz-Nido J, Avila J. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function. Prog Neurobiol 2000; 61: 133-168
23. Macrae IM, Robinson MJ, Graham DI, Reid JL, McCulloch J. Endothelin-1-induced reductions in cerebral blood flow: Dose dependency, time course, and neuropathological consequences. J Cereb Blood Flow Metab 1993; 13: 276-284
24. Sharkey J, Ritchie IM, Kelly PA. Perivascular microapplication of endothelin-1: A new model of focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab 1993; 13: 865-871
25. Fuxe K, Bjelke B, Andbjer B, Grahn H, Rimondini R, Agnati LF. Endothelin-1 induced lesions of the fronto-parietal cortex of the rat. A possible model of focal cortical ischemia. NeuroReport 1997; 8: 2623-2629
26. Biernaskie J, Corbett D, Peeling J, Wells J, Lei H. A serial MR study of cerebral blood flow changes and lesion development following endothelin-1-induced ischemia in rats. Magn Reson Med 2001; 46: 827-830
27. Voorhies AC, Adkins DL and Jones TA. Cortical structural plasticity and behavioral deficits following endothelin-1 induced ischemic lesions of the sensorimotor cortex. Soc Neurosci Abstr 2001; 27: 190
28. Teskey GC, Flynn C, Goertzen CD, Monfils MH, Young NA. Cortical stimulation improves skilled forelimb use following a focal ischemic infarct in the rat. Neurol Res 2003; 25: 794-800
29. Paxinos G, Watson C. The Rat Brain Stereotaxic Coordinates, 2nd Edn, Sydney: Academic Press, 1986
30. Mayhew TM. A review of recent advances in stereology for quantifying neural structure. J Neurocytol 1992; 21: 313-328
31. Hawrylak N, Greenough WT. Monocular deprivation alters the morphology of glial fibrillary acid protein-immunoreactive astrocytes in the rat visual cortex. Brain Res 1995; 683: 187-199
32. Bury SD, Jones TA. Unilateral sensorimotor cortex lesions in adult rats facilitate motor skill learning with the 'Unaffected' forelimb and training-induced dendritic structural plasticity in the motor cortex. J Neurosci 2002; 22: 8597-8606
33. Baddley AJ, Gundersen HJG, Cruz-Orvie LM. Estimation of surface area from vertical sections. J Neurosci Meth 1986; 48: 141-148
34. Bidmon HJ, Jancsik V, Schleicher A, Hagemann G, Witte OW, Woodhams P, Zilles K. Structural alterations and changes in cytoskeletal proteins and proteoglycans after focal cortical ischemia. Neuroscience 1998; 82: 397-420
35. Li Y, Jiang N, Powers C, Chopp M. Neuronal damage and plasticity identified by microtubule-associated protein 2, growth-associated protein 43 and cyclin D1 immunoreactivity after focal cerebral ischemia in rats. Stroke 1998; 29: 1972-1981
36. Schwab M, Antonow-Schlorke I, Zwiener U, Bauer R. Brain-derived peptides reduce the size of cerebral infarction and loss of MAP2 immunoreactivity after focal ischemia in rats. J Neural Transm Suppl. 1998; 53: 299-311
37. Greenough WT, Larson JR, Withers GS. Effects of unilateral and bilateral training in a reaching task on dendritic branching of neurons in the rat sensory-motor forelimb cortex. Behav Neural Biol 1985; 44: 301-314
38. Withers GS, Greenough WT. Reach training selectively alters dendritic branching in subpopulations of Layer II/III pyramids in rat motor-somatosensory forelimb cortex. Neuropsychologia 1989; 27: 61-69
39. Kleim JA, Barbay S, Cooper NR, Hogg TM, Reidel CN, Remple MS, Nudo RJ. Motor learning-dependent synaptogenesis is localized to functionally reorganized motor cortex. Neurobiol Learn Mem 2002; 77: 63-77
40. Plautz EJ, Barbay S, Frost SB, Friel KM, Dancause N, Zoubina EV, Stowe AM, Quaney BM, Nudo RJ. Enhancement of cortical plasticity and behavioral recovery following ischemic stroke using concurrent electrical and rehabilitative therapy: A feasibility study in primates. Neurol Res 2003; 25: 801-810
41. Kleim JA, Bruneau R, VandenBerg P, MacDonald E, McPherson R, Pocock D. Electrical stimulation of motor cortex enhances motor recovery and reduces peri-infarct dysfunction following ischemic insult. Neurol Res 2003; 25: 789-793
42. Brown JA, Lutsep H, Weinand M. Transdural motor cortex stimulation for enhancement of recovery after stroke: Case Report. Neurol Res 2003; 25: 815-818
43. Cramer SC, Benson RR, Burra VC, Himes D, Crafton KR, Janowsky JS, Brown JA, Lutsep HL. Mapping individual brains to guide restorative therapy after stroke: Rationale and pilot studies. Neurol Res 2003; 25: 811-814