Hyperthermia, inducing pancreatic heat-shock proteins, fails to prevent cerulein-induced stress kinase activation

Pancreas

Volumn 19, Issue 2, 1999, Pages 150-157

  Metzler, Wolfgang ^a   Höfken, Thomas ^b   Weber, H ^c   Printz, Hartmut ^a   Göke, Burkhard ^b   Wagner, Andreas C C ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

c Jun kinase; Cerulein pancreatitis; Heat shock proteins; Mitogen activated protein kinases; p38

Indexed keywords

AMYLASE; CERULETIDE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL LIPASE;

AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EDEMA; ENZYME ACTIVATION; HYPERTHERMIA; NONHUMAN; PANCREAS; PANCREATITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; TRIACYLGLYCEROL LIPASE BLOOD LEVEL;

EID: 0345279869     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-199908000-00008     Document Type: Article

References (36)

1. Ray LB, Sturgill TW. Rapid stimulation by insulin of a serine/ threonine kinase in 3T3-L1 adipocytes that phosphorylates microtubule-associated protein 2 in vitro. Proc Natl Acad Sci USA 1987; 84:1502-6.
2. Anderson NG, Maller JL, Tonks NK, Sturgill TW. Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 1990;343:651-3.
3. Crews CM, Erikson RL. Purification of a murine protein tyrosine/ threonine kinase that phosphorylates and activates the Erkl gene product. Proc Natl Acad Sci USA 1992;89:8205-9.
4. Kyriakis JM, App H, Zhang X. Raf-1 activates MAP kinase kinase. Nature 1992;358:417-21.
5. Payne DM, Rossomando AJ, Martino P. Identification of the regulatory phosphorylation sites in pp42/mitogen activated protein kinase (MAP kinase). EMBO J 1991;10:885-92.
6. Huang W, Erikson RL. MAP kinases in multiple signaling pathways. In: Heldin C-H, Purton M, eds. Modular texts in molecular and cell biology 1: signal transduction. London: Chapman & Hall, 1996:159-72.
7. Wan Y, Kurosaki T, Huang X-Y. Tyrosine kinases in activation of the MAP kinase cascade by G-protein coupled receptors. Nature 1996;380:541-4.
8. Kyriakis JM, Banerjee P, Nikolakaki E. The stress activated protein kinase subfamily of c-jun kinases. Nature 1994;69:156-60.
9. Sanchez I, Hughes RT, Mayer BJ. Role of SAPK/ERK kinase-1 in the stress activated pathway regulating transcription factor c-jun. Nature 1994;372:794-8.
10. Han J, Lee J-D, Bibbs L, Ulevitch RJ. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 1994; 265:808-11.
11. Rouse J, Cohen P, Trigon S, et al. A novel kinase cascade triggered by stress and heat shock that stimulates mapkap kinase-2 and phosphorylation of the small heat shock proteins. Cell 1994;78:1027-37.
12. Strowski MZ, Sparmann G, Weber H, et al. Induction of cerulein pancreatitis increases mRNA but reduces protein levels of pancreatic heat shock proteins in rat. Am J Physiol 1997;270:G937-45.
13. Wagner ACC, Weber H, Jonas L, et al. Hyperthermia induces heat shock protein expression and protection against cerulein pancreatitis in rats. Gastroenterology 1996;111:1133-42.
14. Dabrowski A, Grady T, Logsdon CD, Williams JA. Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo. J Biol Chem 1996;271:5686-90.
15. Duan R-D, Williams JA. Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini. Am J Physiol 1994;267:G401-8.
16. Duan R-D, Zheng C-F, Guan K-L, Williams JA. Activation of MAP kinase kinase (MEK) and ras by cholecystokinin in rat pancreatic acini. Am J Physiol 1995;268:G1060-5.
17. Grady T, Dabrowski A, Williams JA, Logsdon CD. Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats. Biochem Biophys Res Commun 1996;227:1-7.
18. Wagner ACC, Metzler M, Weber H, Höfken T, Göke B. p38 Map kinase is expressed in the pancreas and is immediately activated following cerulein hyperstimulation. Digestion (in press).
19. Gabai VL, Meriin AB, Mosser D, et al. HSP70 prevents activation of stress kinases: a novel pathway of cellular thermotolerance. J Biol Chem 1997;272:18033-7.
20. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
21. Wagner ACC, Wishart MJ, Mulders SM, Blevins PM, Andrews PC, Williams JA. GP-3: a newly characterized protein on the inner surface of the zymogen granule membrane undergoes regulated secretion. J Biol Chem 1994;269:9099-104.
22. Gething M-J, Sambrook J. Protein folding in the cell. Nature 1992; 355:33-45.
23. Hartl FU, Hlodan R, Langer T. Molecular chaperones in protein folding: the art of avoiding sticky situations. TIBS 1994;19:20-5.
24. Lindquist S. The heat-shock response. Annu Rev Biochem 1986; 55:1151-91.
25. Welch WJ. Mammalian stress response: cell physiology, structure/ function of stress proteins, and implications for medicine and disease. Physiol Rev 1992;72:1063-81.
26. Mosser DD, Caron AW, Bourget L, Denis-Larose C, Massie B. Role of human heat shock protein HSP70 in protection against stress-induced apoptosis. Mol Cell Biol 1997;17:5317-27.
27. Frossard JL, Saluja A, Lee HS, et al. Heat shock protein 70 (HSP70) expression reduces the severity of caerulein-induced pancreatitis by reducing intrapancreatic active trypsin levels. Gastroenterology 1998;114:A330.
28. Grise K, Kim F, McFadden D. Hyperthermia-induced expression of heat shock protein prevents death in necrotizing pancreatitis. Gastroenterology 1998;114:A334.
29. Verheij M, Bose R, Lin X-H. et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 1996;380:75-9.
30. Xia Z, Dickens M, Raingeaud J, Davis R, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995;270:1326-31.
31. Zanke BW, Boudreau K, Rubie E, et al. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Biol 1996;6:606-13.
32. Samali A, Gotter TG. Heat shock proteins increase resistance to apoptosis. Exp Cell Res 1996;223:163-70.
33. Jaattela M, Wissing D, Bauer PC, Li GC. Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. EMBO J 1992;11:3507-12.
34. Li WX, Cher, CH, Ling CC, Li GC. Apoptosis in heat induced cell killing: the protective role of HSP70 and the sensitization effect of the c-myc gene. Radiat Res 1996;145:324-30.
35. Kaiser AM. Saluja AK, Sengupta A, Saluja M, Steer ML. Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol 1995;269:C1295-304.
36. Saluja A, Hofbauer B, Yamaguchi Y, Yamanak K, Steer ML. Induction of apoptosis reduces severity of cerulein-induced pancreatitis in mice. Biochem Biophys Res Commun 1996;220;875-8.