Children with type-1 diabetes and their unaffected siblings have fewer symptoms of asthma

Lancet

Volumn 353, Issue 9167, 1999, Pages 1850-

  Douek, Isabelle F ^a   Leech, Nicola J ^a   Gillmor, Hilary A ^a   Bingley, Polly J ^a   Gale, Edwin A M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASTHMA; CHILD; DISEASE ASSOCIATION; HELPER CELL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK; SIBLING; SYMPTOMATOLOGY; WHEEZING;

EID: 0345279849     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(99)00988-5     Document Type: Article

References (5)

1. The EURODIAB ACE Substudy 2 Study Group. Decreased prevalence of atopy in diabetic children. Diabetologia 1998; 41 (suppl 1): A22 (abstr).
2. Kaur B, Ross Anderson H, Austin J, et al. Prevalence of asthma symptoms, diagnosis, and treatment in 12-14 year old children across Great Britain (International Study of Asthma and Allergies in Childhood, ISAAC, UK). BMJ 1998; 316: 118-24.
3. Bingley PJ, Gale EAM. The incidence of insulin-dependent diabetes in England: a study in the Oxford region 1985-86. BMJ 1989; 298: 558-60.
4. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 1998; 351: 1225-32.
5. Rapoport MJ, Jaramillo A, Zipris D, et al. Interleukin 4 reverses T cell proliferation unresponsiveness and prevents the onset of diabetes in non-obese diabetic mice. J Exp Med 1993; 178: 87-99.