Proliferation of antigen MIB-1 in metastatic carcinoid tumours removed at liver transplantation: Relevance to prognosis

European Journal of Gastroenterology and Hepatology

Volumn 15, Issue 2, 2003, Pages 139-143

  Amarapurkar, Anjali D ^a   Davies, Albert ^a   Ramage, John K ^a   Stangou, Arie J ^a   Wight, Derek G D ^b   Portmann, Bernard C ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

APUDOMA; Carcinoid tumour; Cell proliferation; Liver metastasis; Liver transplantation; MIB 1

Indexed keywords

ANTIGEN; CHROMOGRANIN; EOSIN; FORMALDEHYDE; HEMATOXYLIN; KI 67 ANTIGEN; PARAFFIN; PEROXIDASE; TUMOR MARKER; UNCLASSIFIED DRUG;

AGE; ANTIBODY LABELING; ANTIGEN DETECTION; ARTICLE; CANCER INVASION; CANCER SURVIVAL; CARCINOID; CELL PROLIFERATION; CLINICAL FEATURE; CORRELATION ANALYSIS; DISEASE ACTIVITY; DISEASE MARKER; GENDER; HISTOLOGY; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; LIVER TRANSPLANTATION; NEUROENDOCRINE TUMOR; PARAMETER; PREDICTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL RATE; TISSUE SECTION; TUMOR RECURRENCE;

ADULT; ANTIGENS, NEOPLASM; APUDOMA; CARCINOID TUMOR; CELL DIVISION; FEMALE; GASTROINTESTINAL NEOPLASMS; HUMANS; KI-67 ANTIGEN; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PREDICTIVE VALUE OF TESTS; PROGNOSIS; TIME FACTORS;

EID: 0345270001     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200302000-00006     Document Type: Article

References (26)

1. Caplin ME, Buscombe JR, Hilson AJ, Jones AL, Watkinson AF, Burroughs AK. Carcinoid tumour. Lancet 1998; 352:799-805.
2. Routley D, Ramage JK, McPeake J, Tan KC, Williams R. Orthotopic liver transplantation in the treatment of metastatic neuroendocrine tumours of the liver. Liver Transpl Surg 1995; 1:118-121.
3. Schweizer RT, Alsina AE, Rosson R, Bartus SA. Liver transplantation for metastatic neuroendocrine tumours. Transplant Proc 1993; 25:1973.
4. Ramage JK, Catnach SM, William R. Overview; the management of metastatic carcinoid tumours. Liver Transpl Surg 1995; 1:107-110.
5. Dousset B, Houssin D, Soubrane O, Boillot O, Baudin F, Chapuis Y, et al. Metastatic endocrine tumours: is there a place for liver transplantation? Liver Transpl Surg 1995; 1:111-117.
6. Makowka L, Tzakis AG, Mazzaferro V, Teperman L, Demetris AJ, Iwatsuki S, et al. Transplantation of the liver for metastatic endocrine tumours of the intestine and pancreas. Surg Gynecol Obstet 1989; 168:107-111.
7. Koide N, Watanabe H, Shimozawa N, Hanazaki K, Kajikawa S, Adachi W. et al. Four resections for hepatic metastasis from gastric cancer: histochemical analysis of cell proliferation, apoptosis and angiogenesis. J Gastroenterol 2000; 35:150-154.
8. De Jong KP, Stellema R, Karrenbeld A, Koudstaal J, Gouw AS, Sluiter WJ, et al. Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53 and Ki 67 in colorectal liver metastasis and corresponding primary tumours. Hepatology 1998; 28:971-979.
9. Cheville JC, Terrell RB, Cohen MB. Use of proliferative marker Ki67 (MIB 1) and proliferating cell nuclear antigen (PC10) in transitional cell carcinoma of the renal pelvis. Mod Pathol 1994; 7:794-799.
10. Beck T, Weller EE, Weikel W, Brumm C, Wilkens C, Knapstein PG. Usefulness of immunohistochemical staining for p 53 in the prognosis of breast carcinoma: correlation with established prognosis parameters and with the proliferative marker, MIB-1. Gynecol Oncol 1995; 57:96-104.
11. Katoh R, Bray CE, Susuki K, Komiyama A, Hemmi A, Kawaoi A, et al. Growth activity in hyperplastic and neoplastic human thyroid determined by an immunohistochemical staining procedure using monoclonal antibody MIB-1. Hum Pathol 1995; 26:139-146.
12. Von Herbay A, Sieg B, Schürmann G, Hofmann WJ, Betzler M, Otto HF. Proliferative activity of neuroendocrine tumours of the gastroenteropancreatic endocrine system: DNA flow cytometry and immunohistological investigations. Gut 1991; 32:949-953.
13. Cattoretti G, Becker MH, Key G, Duchrow M, Schluter C, Galle J, et al. Monoclonal antibodies against recombinant parts of the Ki67 antigen (MIB1 and MIB3) detect proliferating cells in microwave-processed formalin fixed paraffin sections. J Pathol 1992; 168:357-363.
14. Ara T, Fukuzawa M, Oue T, Komoto Y, Kusafuka T, Imura K, et al. Immunohistochemical assessment of the MIB 1 labelling index in human hepatoblastoma and its prognostic relevance. J Pediatr Surg 1997; 32:1690-1694.
15. King KL, Hwang JJ, Chau GY, Tsay SH, Chi CW, Lee TG, et al. Ki 67 expression as a prognostic marker in patients with hepatocellular carcinoma. J Gastroenterol Hepatol 1998; 13:273-279.
16. Yoon DS, Cheong JH, Park YN, Kwon SW, Chi HS, Kim BR. Cell proliferative index and the expression of p53 and Bcl-2 in tumourous and non tumourous lesions of hepatocellular carcinoma and metastatic liver cancer. Yonsei Med J 1998; 39:424-429.
17. Nolte M, Werner M, Nasarek A, Bektas H, von Wasielewski R, Klempnauer J, et al. Expression of proliferation associated antigen and detection of numerical chromosome aberrations in primary human liver tumours: relevance to tumour characteristics and prognosis. J Clin Pathol 1998; 51:47-51.
18. Haak HR, Fleuren GJ. Neuroendocrine differentiation of adrenocortical tumours. Cancer 1995; 75:860-864.
19. Chan JKC, Tsang WYW. Endocrine malignancies that may mimic benign lesions. Semin Diagn Pathol 1995; 12:45-63.
20. Chaudhry A, Oberg K, Wilander EA. A study of biological behaviour based on the expression of a proliferating antigen in neuroendocrine tumors of the digestive system. Tumour Biol 1992; 13:27-35.
21. Pelosi G, Zamboni G, Doglioni C, Rodella S, Bresaola E, Iacono C, et al. Immunodetection of proliferating cell nuclear antigen assesses the growth fraction and predicts malignancy in endocrine tumors of the pancreas. Am J Surg Pathol 1992; 16:1215-1225.
22. Gentil Perret A, Mosnier JF, Buono JP, Berthelot P, Chipponi J, Balique JG, et al. The relationship between MIB-1 proliferation index and outcome in pancreatic neuroendocrine tumors. Am J Clin Pathol 1998; 109:286-293.
23. Costes V, Marty-Ane C, Picot MC, Serre I, Pujol JL, Mary H, et al. Typical and atypical bronchopulmonary carcinoid tumors: a clinicopathologic and Ki-67-labeling study. Hum Pathol 1995; 26:740-745.
24. Zirbes TK, Lorenzen J, Baldus SE, Moenig SP, Wolters U, Ottlik A, et al. Apoptosis and expression of bcl-2 protein are inverse factors influencing tumour cell turnover in primary carcinoid tumours of the lung. Histopathology 1998; 33:123-128.
25. Bohm J, Koch S, Gais P, Jutting U, Prauer HW, Hofler H. Prognostic value of MIB-1 in neuroendocrine tumours of the lung. J Pathol 1996; 178:402-409.
26. Rosenau J, Bahr MJ, von Wasielewski R, Mengel M, Schmidt HH, Nashan B, et al. Ki67, E-cadherin, and p53 as prognostic indicators of long-term outcome after liver transplantation for metastatic neuroendocrine tumors. Transplantation 2002; 73:386-394.