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Volumn 58, Issue 4, 2003, Pages 311-316

T cell cytokine profiles in childhood asthma

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; IONOMYCIN; LYMPHOCYTE SURFACE MARKER; MONENSIN; PHORBOL 13 ACETATE 12 MYRISTATE;

EID: 0345269859     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thorax.58.4.311     Document Type: Article
Times cited : (58)

References (62)
  • 1
    • 0022640843 scopus 로고
    • Two types of murine helper T-cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, et al. Two types of murine helper T-cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3
  • 2
    • 0030776790 scopus 로고    scopus 로고
    • Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma
    • Humbert M, Corrigan CJ, Kimmitt P, et al. Relationship between IL-4 and IL-5 mRNA expression and disease severity in atopic asthma. Am J Respir Crit Care Med 1997;156:704-8.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 704-708
    • Humbert, M.1    Corrigan, C.J.2    Kimmitt, P.3
  • 3
    • 0027320031 scopus 로고
    • Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen challenge in patients with atopic asthma
    • Robinson DS, Hamid Q, Bentley A, et al. Activation of CD4+ T cells, increased Th2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen challenge in patients with atopic asthma. J Allergy Clin Immunol 1993;92:313-24.
    • (1993) J Allergy Clin Immunol , vol.92 , pp. 313-324
    • Robinson, D.S.1    Hamid, Q.2    Bentley, A.3
  • 4
    • 0026610142 scopus 로고
    • Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • Robinson DS, Hamid Q, Ying S, et al. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
    • (1992) N Engl J Med , vol.326 , pp. 298-304
    • Robinson, D.S.1    Hamid, Q.2    Ying, S.3
  • 5
    • 0030863684 scopus 로고    scopus 로고
    • Bronchoalveolar lavage findings suggest two different forms of childhood asthma
    • Stevenson EC, Turner G, Heaney LG, et al. Bronchoalveolar lavage findings suggest two different forms of childhood asthma. Clin Exp Allergy 1997;27:1027-35.
    • (1997) Clin Exp Allergy , vol.27 , pp. 1027-1035
    • Stevenson, E.C.1    Turner, G.2    Heaney, L.G.3
  • 6
    • 0029790448 scopus 로고    scopus 로고
    • Investigating paediatric airways by non-bronchoscopic lavage: Normal cellular data
    • Heaney LG, Stevenson EC, Turner G, et al. Investigating paediatric airways by non-bronchoscopic lavage: normal cellular data. Clin Exp Allergy 1996;26:799-806.
    • (1996) Clin Exp Allergy , vol.26 , pp. 799-806
    • Heaney, L.G.1    Stevenson, E.C.2    Turner, G.3
  • 7
    • 0030119169 scopus 로고    scopus 로고
    • T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma
    • Krug N, Madden J, Redington AE, et al. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 1996;14:319-26.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 319-326
    • Krug, N.1    Madden, J.2    Redington, A.E.3
  • 9
    • 0026654595 scopus 로고
    • Internalization, lysosomal degradation and new synthesis of surface membrane CD4 in phorbol ester-activated T-lymphocytes and U-937 cells
    • Petersen CM, Christensen EI, Andresen BS, et al. Internalization, lysosomal degradation and new synthesis of surface membrane CD4 in phorbol ester-activated T-lymphocytes and U-937 cells. Exp Cell Res 1992;201:160-73.
    • (1992) Exp Cell Res , vol.201 , pp. 160-173
    • Petersen, C.M.1    Christensen, E.I.2    Andresen, B.S.3
  • 10
    • 0025278511 scopus 로고
    • Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry
    • Loken MR, Brosnan JM, Bach BA, et al. Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry. Cytometry 1990;11:453-9.
    • (1990) Cytometry , vol.11 , pp. 453-459
    • Loken, M.R.1    Brosnan, J.M.2    Bach, B.A.3
  • 11
    • 0023691938 scopus 로고
    • Modified histogram subtraction technique for analysis of flow cytometry data
    • Overton WR. Modified histogram subtraction technique for analysis of flow cytometry data. Cytometry 1988;9:619-26.
    • (1988) Cytometry , vol.9 , pp. 619-626
    • Overton, W.R.1
  • 12
    • 0030809939 scopus 로고    scopus 로고
    • Intracellular cytokine expression in whole blood preparations from normals and patients with atopic dermatitis
    • Ferry B, Antrobus P, Huzicka I, et al. Intracellular cytokine expression in whole blood preparations from normals and patients with atopic dermatitis. Clin Exp Immunol 1997;110:410-7.
    • (1997) Clin Exp Immunol , vol.110 , pp. 410-417
    • Ferry, B.1    Antrobus, P.2    Huzicka, I.3
  • 13
    • 0034131336 scopus 로고    scopus 로고
    • Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma: Increased IFN-gamma-producing CD8(+) T cells in asthma
    • Magnan AO, Mely LG, Camilla CA, et al. Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma: increased IFN-gamma-producing CD8(+) T cells in asthma. Am J Respir Crit Care Med 2000;161:1790-6.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1790-1796
    • Magnan, A.O.1    Mely, L.G.2    Camilla, C.A.3
  • 14
    • 0032820811 scopus 로고    scopus 로고
    • Flow cytometric detection of type 1 (IL-2, IFN-gamma) and type 2 (IL-4, IL-5) cytokines in T-helper and T-suppressor/cytotoxic cells in rheumatoid arthritis, allergic asthma and atopic dermatitis
    • Schuerwegh AJ, De Clerck LS, De Schutter L, et al. Flow cytometric detection of type 1 (IL-2, IFN-gamma) and type 2 (IL-4, IL-5) cytokines in T-helper and T-suppressor/cytotoxic cells in rheumatoid arthritis, allergic asthma and atopic dermatitis. Cytokine 1999;11:783-8.
    • (1999) Cytokine , vol.11 , pp. 783-788
    • Schuerwegh, A.J.1    De Clerck, L.S.2    De Schutter, L.3
  • 15
    • 0032991043 scopus 로고    scopus 로고
    • Intracellular interferon-gamma (IFNγ) production in normal children and children with atopic dermatitis
    • Campbell DE, Fryga AS, Bol S, et al. Intracellular interferon-gamma (IFNγ) production in normal children and children with atopic dermatitis. Clin Exp Immunol 1999;115:377-82.
    • (1999) Clin Exp Immunol , vol.115 , pp. 377-382
    • Campbell, D.E.1    Fryga, A.S.2    Bol, S.3
  • 16
    • 0032861843 scopus 로고    scopus 로고
    • Cytokine profiles of BAL T cells and T-cell clones obtained from human asthmatic airways after local allergen challenge
    • Bodey KJ, Semper AE, Redington AE, et al. Cytokine profiles of BAL T cells and T-cell clones obtained from human asthmatic airways after local allergen challenge. Allergy 1999;54:1083-93.
    • (1999) Allergy , vol.54 , pp. 1083-1093
    • Bodey, K.J.1    Semper, A.E.2    Redington, A.E.3
  • 17
    • 0034914913 scopus 로고    scopus 로고
    • Cytokine profile of bronchoalveolar lavage-derived CD4(+), CD8(+), and gammadelta T cells in people with asthma after segmental allergen challenge
    • Krug N, Erpenbeck VJ, Balke K, et al. Cytokine profile of bronchoalveolar lavage-derived CD4(+), CD8(+), and gammadelta T cells in people with asthma after segmental allergen challenge. Am J Respir Cell Mol Biol 2001;25:125-31.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 125-131
    • Krug, N.1    Erpenbeck, V.J.2    Balke, K.3
  • 18
    • 0027536245 scopus 로고
    • Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma
    • Cembrzynska-Nowak M, Szlarze E, Inglot AD, et al. Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma. Am Rev Respir Dis 1993;147:291-5.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 291-295
    • Cembrzynska-Nowak, M.1    Szlarze, E.2    Inglot, A.D.3
  • 19
    • 0031911281 scopus 로고    scopus 로고
    • Elevated serum interferon-γ in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation
    • tenHacken NHT, Oosterhoff Y, Kauffman HF, et al. Elevated serum interferon-γ in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation. Eur Respir J 1998;11:312-6.
    • (1998) Eur Respir J , vol.11 , pp. 312-316
    • TenHacken, N.H.T.1    Oosterhoff, Y.2    Kauffman, H.F.3
  • 20
    • 0025265156 scopus 로고
    • CD4 T-lymphocyte activation in acute severe asthma
    • Corrigan CJ, Kay AB. CD4 T-lymphocyte activation in acute severe asthma. Am J Respir Dis 1990;141:970-7.
    • (1990) Am J Respir Dis , vol.141 , pp. 970-977
    • Corrigan, C.J.1    Kay, A.B.2
  • 21
    • 0028176866 scopus 로고
    • Lesional expression of interferon-gamma in atopic eczema
    • Grewe M, Gyufko K, Schopf E, et al. Lesional expression of interferon-gamma in atopic eczema. Lancet 1994:343;25-6.
    • (1994) Lancet , vol.343 , pp. 25-26
    • Grewe, M.1    Gyufko, K.2    Schopf, E.3
  • 22
    • 0032433669 scopus 로고    scopus 로고
    • T lymphocytes that infiltrate nasar polyps have a specialized phenotype and produce a mixed Th1/Th2 pattern of cytokines
    • Sanchez-Segura A, Brieva JA, Rodriguez C. T lymphocytes that infiltrate nasar polyps have a specialized phenotype and produce a mixed Th1/Th2 pattern of cytokines. J Allergy Clin Immunol 1998;102:953-60.
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 953-960
    • Sanchez-Segura, A.1    Brieva, J.A.2    Rodriguez, C.3
  • 23
    • 0027500622 scopus 로고
    • IL4 and interferon gamma production in children with atopic disease
    • Tang M, Kemp A, Varigos G. IL4 and interferon gamma production in children with atopic disease. Clin Exp Immunol 1993;92:120-4.
    • (1993) Clin Exp Immunol , vol.92 , pp. 120-124
    • Tang, M.1    Kemp, A.2    Varigos, G.3
  • 24
    • 0029052010 scopus 로고
    • Interleukin-4 and interferon-gamma production in atopic and non-atopic children with asthma
    • Tang ML, Coleman J, Kemp AS. Interleukin-4 and interferon-gamma production in atopic and non-atopic children with asthma. Clin Exp Allergy 1995;25:515-21.
    • (1995) Clin Exp Allergy , vol.25 , pp. 515-521
    • Tang, M.L.1    Coleman, J.2    Kemp, A.S.3
  • 25
    • 0033961137 scopus 로고    scopus 로고
    • Nonatopic wheezy children have reduced interferon-gamma
    • Leech SC, Price JF, Holmes BJ, et al. Nonatopic wheezy children have reduced interferon-gamma. Allergy 2000;55:74-8.
    • (2000) Allergy , vol.55 , pp. 74-78
    • Leech, S.C.1    Price, J.F.2    Holmes, B.J.3
  • 26
    • 0034959063 scopus 로고    scopus 로고
    • The usefulness of competitive PCR: Airway gene expression of IL-5, IL-4, IL-4δ2, IL-2, and IFNγ in asthma
    • Glare EM, Divjak M, Bailey MJ, et al. The usefulness of competitive PCR: airway gene expression of IL-5, IL-4, IL-4δ2, IL-2, and IFNγ in asthma. Thorax 2001;56:541-8.
    • (2001) Thorax , vol.56 , pp. 541-548
    • Glare, E.M.1    Divjak, M.2    Bailey, M.J.3
  • 27
    • 0031093680 scopus 로고    scopus 로고
    • Development of airway hyperresponsiveness is dependent on interferon-gamma and independent of eosinophil infiltration
    • Hessel EM, Van Oosterhout AJ, Van Ark I, et al. Development of airway hyperresponsiveness is dependent on interferon-gamma and independent of eosinophil infiltration. Am J Respir Cell Mol Biol 1997;16:325-34.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 325-334
    • Hessel, E.M.1    Van Oosterhout, A.J.2    Van Ark, I.3
  • 28
    • 0032982284 scopus 로고    scopus 로고
    • Detection of intracellular cytokines in human lymphocytes and monocytes at the single cell level by flow cytometry
    • Gagro A, Rabatic S, Ivancic I, et al. Detection of intracellular cytokines in human lymphocytes and monocytes at the single cell level by flow cytometry. Periodicum Biologorum 1999;101:17-26.
    • (1999) Periodicum Biologorum , vol.101 , pp. 17-26
    • Gagro, A.1    Rabatic, S.2    Ivancic, I.3
  • 29
    • 0029302202 scopus 로고
    • Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects
    • Ying S, Durham SR, Corrigan CJ, et al. Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am J Respir Cell Mol Biol 1995;12:477-87.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 477-487
    • Ying, S.1    Durham, S.R.2    Corrigan, C.J.3
  • 30
    • 0033674403 scopus 로고    scopus 로고
    • Inflammatory response in induced sputum mononuclear cells from patients with acute exacerbation of asthma
    • Hamzaoui A, Brahim MB, Zhioua A, et al. Inflammatory response in induced sputum mononuclear cells from patients with acute exacerbation of asthma. Mediat Inflamm 2000;9:147-53.
    • (2000) Mediat Inflamm , vol.9 , pp. 147-153
    • Hamzaoui, A.1    Brahim, M.B.2    Zhioua, A.3
  • 31
    • 0028432404 scopus 로고
    • Interleukin-4-dependent pulmonary eosinophil infiltration in a murine model of asthma
    • Lukacs NW, Strieter RM, Chensue SW, et al. Interleukin-4-dependent pulmonary eosinophil infiltration in a murine model of asthma. Am J Respir Cell Mol Biol 1994;10:526-32.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 526-532
    • Lukacs, N.W.1    Strieter, R.M.2    Chensue, S.W.3
  • 32
    • 0031004365 scopus 로고    scopus 로고
    • Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice
    • Gavett SH, Ohearn DJ, Karp CL, et al. Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice. Am J Physiol 1997;272:L253-61.
    • (1997) Am J Physiol , vol.272
    • Gavett, S.H.1    Ohearn, D.J.2    Karp, C.L.3
  • 33
    • 0032531571 scopus 로고    scopus 로고
    • Cutting edge: IL4 independent induction of airway hyperresponsiveness by Th2, but not Th1 cells
    • Cohn L, Tepper JS, Bottomly K. Cutting edge: IL4 independent induction of airway hyperresponsiveness by Th2, but not Th1 cells. J Immunol 1998;161:3813-6.
    • (1998) J Immunol , vol.161 , pp. 3813-3816
    • Cohn, L.1    Tepper, J.S.2    Bottomly, K.3
  • 34
    • 0030953977 scopus 로고    scopus 로고
    • Aeroallergen-induced eosinophilic inflammation, lung damage and airways hyperreactivity in mice can occur independently of IL4 and allergen-specific immunoglobulins
    • Hogan SP, Mould A, Kikutani H, et al. Aeroallergen-induced eosinophilic inflammation, lung damage and airways hyperreactivity in mice can occur independently of IL4 and allergen-specific immunoglobulins. J Clin Invest 1997;99:1329-39.
    • (1997) J Clin Invest , vol.99 , pp. 1329-1339
    • Hogan, S.P.1    Mould, A.2    Kikutani, H.3
  • 35
    • 0030048946 scopus 로고    scopus 로고
    • Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa
    • Bentley AM, Hamid Q, Robinson DS, et al. Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am J Respir Crit Care Med 1996;153:551-6.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 551-556
    • Bentley, A.M.1    Hamid, Q.2    Robinson, D.S.3
  • 36
    • 0031883096 scopus 로고    scopus 로고
    • Induction of interleukin-4 and interleukin-5 expression in mast cells is inhibited by glucocorticoids
    • Sewell WA, Scurr LL, Orphanides H, et al. Induction of interleukin-4 and interleukin-5 expression in mast cells is inhibited by glucocorticoids. Clin Diagn Lab Immunol 1998;5:18-23.
    • (1998) Clin Diagn Lab Immunol , vol.5 , pp. 18-23
    • Sewell, W.A.1    Scurr, L.L.2    Orphanides, H.3
  • 37
    • 0027183057 scopus 로고
    • Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression
    • Robinson D, Hamid Q, Ying S, et al. Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5, and interferon-gamma cytokine gene expression. Am Rev Respir Dis 1993;148:401-6.
    • (1993) Am Rev Respir Dis , vol.148 , pp. 401-406
    • Robinson, D.1    Hamid, Q.2    Ying, S.3
  • 38
    • 0028336936 scopus 로고
    • Regulation of IgE production by beta-2-adrenoreceptor agonists
    • Coqueret O, Lagent V, Frere CP, et al. Regulation of IgE production by beta-2-adrenoreceptor agonists. Ann NY Acad Sci 1994;725:44-9.
    • (1994) Ann NY Acad Sci , vol.725 , pp. 44-49
    • Coqueret, O.1    Lagent, V.2    Frere, C.P.3
  • 39
    • 0030203501 scopus 로고    scopus 로고
    • Cytokine production by T-cell clones from bronchoalveolar lavage fluid of patients with asthma and healthy subjects
    • Krouwels FH, Hol BE, Bruinier B, et al. Cytokine production by T-cell clones from bronchoalveolar lavage fluid of patients with asthma and healthy subjects. Eur Respir J Suppl 1996;22:95-103s.
    • (1996) Eur Respir J Suppl , vol.22
    • Krouwels, F.H.1    Hol, B.E.2    Bruinier, B.3
  • 40
    • 0029302202 scopus 로고
    • Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5 and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects
    • Ying S, Durham SR, Corrigan CJ, et al. Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5 and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am J Respir Cell Mol Biol 1995;12:477-87.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 477-487
    • Ying, S.1    Durham, S.R.2    Corrigan, C.J.3
  • 41
    • 0031753995 scopus 로고    scopus 로고
    • Frequencies of T cells expressing interleukin-4 and interleukin-5 in atopic asthmatic children
    • Krug N, Jung T, Napp U, et al. Frequencies of T cells expressing interleukin-4 and interleukin-5 in atopic asthmatic children. Am J Respir Crit Care Med 1998;158:754-9.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 754-759
    • Krug, N.1    Jung, T.2    Napp, U.3
  • 42
    • 0025740415 scopus 로고
    • Serum levels of soluble IL-2 receptor, IL-4 and IgE-binding factors in childhood allergic diseases
    • Matsumoto T, Miike T, Yamaguchi K, et al. Serum levels of soluble IL-2 receptor, IL-4 and IgE-binding factors in childhood allergic diseases. Clin Exp Immunol 1991;85:288-92.
    • (1991) Clin Exp Immunol , vol.85 , pp. 288-292
    • Matsumoto, T.1    Miike, T.2    Yamaguchi, K.3
  • 43
    • 0031110132 scopus 로고    scopus 로고
    • Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics
    • Ying S, Humbert M, Barkans J, et al. Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics. J Immunol 1997;158:3539-44.
    • (1997) J Immunol , vol.158 , pp. 3539-3544
    • Ying, S.1    Humbert, M.2    Barkans, J.3
  • 44
    • 0028432821 scopus 로고
    • Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: Evidence for the human mast cell as a source of these cytokines
    • Bradding P, Roberts JA, Britten KM, et al. Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines. Am J Respir Cell Mol Biol 1994;10:471-80.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 471-480
    • Bradding, P.1    Roberts, J.A.2    Britten, K.M.3
  • 45
    • 0028168602 scopus 로고
    • Reduced interferan-gamma secretion with increased mRNA expression in and atopic dermatitis: Evidence for a post-transcriptional defect
    • Tang MLK, Varigas GA, Kemp AS. Reduced interferan-gamma secretion with increased mRNA expression in and atopic dermatitis: evidence for a post-transcriptional defect. Clin Exp Immunol 1994;97:483-90.
    • (1994) Clin Exp Immunol , vol.97 , pp. 483-490
    • Tang, M.L.K.1    Varigas, G.A.2    Kemp, A.S.3
  • 46
    • 0029982434 scopus 로고    scopus 로고
    • Endobronchial secretion of interleukin-13 fallowing local alrergen challenge in atopic asthma: Relationship to interleukin-4 and eosinophil counts
    • Kroegel C, Julius P, Matthys H, et al. Endobronchial secretion of interleukin-13 fallowing local alrergen challenge in atopic asthma: relationship to interleukin-4 and eosinophil counts. Eur Respir J 1996;9:899-904.
    • (1996) Eur Respir J , vol.9 , pp. 899-904
    • Kroegel, C.1    Julius, P.2    Matthys, H.3
  • 47
    • 0030922389 scopus 로고    scopus 로고
    • Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
    • Humbert M, Durham SR, Kimmitt P, et al. Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma. J Allergy Clin Immunol 1997;99:657-65.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 657-665
    • Humbert, M.1    Durham, S.R.2    Kimmitt, P.3
  • 48
    • 0029038120 scopus 로고
    • IL-13 expression at the sites of allergen challenge in patients with asthma
    • Huang SK, Xiao HQ, Kleine-Tebbe J, et al. IL-13 expression at the sites of allergen challenge in patients with asthma. J Immunol 1995;155:2688-94.
    • (1995) J Immunol , vol.155 , pp. 2688-2694
    • Huang, S.K.1    Xiao, H.Q.2    Kleine-Tebbe, J.3
  • 50
    • 0035888720 scopus 로고    scopus 로고
    • Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype?
    • Salvi SS, Babu KS, Holgate ST. Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype? Am J Respir Crit Care Med 2001;164:1343-6.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1343-1346
    • Salvi, S.S.1    Babu, K.S.2    Holgate, S.T.3
  • 51
    • 0029981818 scopus 로고    scopus 로고
    • Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: An immunocytochemical study
    • Thepen T, Langeveld-Wildschut EG, Bihari IC, et al. Biphasic response against aeroallergen in atopic dermatitis showing a switch from an initial TH2 response to a TH1 response in situ: an immunocytochemical study. J Allergy Clin Immunol 1996;97:828-37.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 828-837
    • Thepen, T.1    Langeveld-Wildschut, E.G.2    Bihari, I.C.3
  • 53
    • 0028990124 scopus 로고
    • Community study of role of viral infections in exacerbations of asthma in 9-11 year old children
    • Johnston SL, Pattemore PK, Sanderson G, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ 1995;310:1225-9.
    • (1995) BMJ , vol.310 , pp. 1225-1229
    • Johnston, S.L.1    Pattemore, P.K.2    Sanderson, G.3
  • 54
    • 0035055865 scopus 로고    scopus 로고
    • Epidemiologic and clinical evidence of a respiratory syncytial virus-reactive airway disease link
    • Sigurs N. Epidemiologic and clinical evidence of a respiratory syncytial virus-reactive airway disease link. Am J Respir Crit Care Med 2001;163:S2-6.
    • (2001) Am J Respir Crit Care Med , vol.163
    • Sigurs, N.1
  • 55
    • 0031735230 scopus 로고    scopus 로고
    • Intracellular IFN-gamma expression in natural killer cells precedes lung CD8+ T cell recruitment during respiratory syncytial virus infection
    • Hussell T, Openshaw PJ. Intracellular IFN-gamma expression in natural killer cells precedes lung CD8+ T cell recruitment during respiratory syncytial virus infection. J Gen Virol 1998;79:2593-601.
    • (1998) J Gen Virol , vol.79 , pp. 2593-2601
    • Hussell, T.1    Openshaw, P.J.2
  • 56
    • 0033921492 scopus 로고    scopus 로고
    • Th-1- and Th-2-type cytokine expression by activated T lymphocytes from the lung and spleen during the inflammatory response to respiratory syncytial virus
    • Tripp RA, Moore D, Anderson LJ. Th-1- and Th-2-type cytokine expression by activated T lymphocytes from the lung and spleen during the inflammatory response to respiratory syncytial virus. Cytokine 2000;12:801-7.
    • (2000) Cytokine , vol.12 , pp. 801-807
    • Tripp, R.A.1    Moore, D.2    Anderson, L.J.3
  • 57
    • 0031058331 scopus 로고    scopus 로고
    • Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL-12, IFN-gamma)
    • Trinchieri G. Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL-12, IFN-gamma). Curr Opin Immunol 1997;9:17-23.
    • (1997) Curr Opin Immunol , vol.9 , pp. 17-23
    • Trinchieri, G.1
  • 58
    • 0034817716 scopus 로고    scopus 로고
    • Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: Risk factors and regulatory role of IFN-gamma, IL-4 and IL-10
    • van der Velden V, Laan MP, Baert MR, et al. Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: risk factors and regulatory role of IFN-gamma, IL-4 and IL-10. Clin Exp Allergy 2001;31:997-1006.
    • (2001) Clin Exp Allergy , vol.31 , pp. 997-1006
    • Van Der Velden, V.1    Laan, M.P.2    Baert, M.R.3
  • 59
    • 0032698748 scopus 로고    scopus 로고
    • Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation
    • Randolph DA, Stephens R, Carruthers CJ, et al. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation. J Clin Invest 1999;104:1021-9.
    • (1999) J Clin Invest , vol.104 , pp. 1021-1029
    • Randolph, D.A.1    Stephens, R.2    Carruthers, C.J.3
  • 60
    • 0029148642 scopus 로고
    • Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry
    • Picker MK, Singh Z, Zdraveski JR, et al. Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 1995;86:1408-19.
    • (1995) Blood , vol.86 , pp. 1408-1419
    • Picker, M.K.1    Singh, Z.2    Zdraveski, J.R.3
  • 61
    • 0034699514 scopus 로고    scopus 로고
    • Flow cytometric measurement of intracellular cytokines
    • Pala P, Hussell T, Openshaw PJ. Flow cytometric measurement of intracellular cytokines. J Immunol Methods 2000;243:107-24.
    • (2000) J Immunol Methods , vol.243 , pp. 107-124
    • Pala, P.1    Hussell, T.2    Openshaw, P.J.3
  • 62
    • 0031472435 scopus 로고    scopus 로고
    • Simultaneous detection of DNA synthesis and cytokine production in staphylococcal entertoxin B activated CD4+ T lymphocytes by flow cytometry
    • Mehta BA, Maino VC. Simultaneous detection of DNA synthesis and cytokine production in staphylococcal entertoxin B activated CD4+ T lymphocytes by flow cytometry. J Immunol Methods 1997;208:49-59.
    • (1997) J Immunol Methods , vol.208 , pp. 49-59
    • Mehta, B.A.1    Maino, V.C.2


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